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Items: 1 to 20 of 340

1.

The unfolded protein response transducer IRE1α prevents ER stress-induced hepatic steatosis.

Zhang K, Wang S, Malhotra J, Hassler JR, Back SH, Wang G, Chang L, Xu W, Miao H, Leonardi R, Chen YE, Jackowski S, Kaufman RJ.

EMBO J. 2011 Apr 6;30(7):1357-75. doi: 10.1038/emboj.2011.52. Epub 2011 Mar 15.

2.

Fibroblast growth factor 21 is regulated by the IRE1α-XBP1 branch of the unfolded protein response and counteracts endoplasmic reticulum stress-induced hepatic steatosis.

Jiang S, Yan C, Fang QC, Shao ML, Zhang YL, Liu Y, Deng YP, Shan B, Liu JQ, Li HT, Yang L, Zhou J, Dai Z, Liu Y, Jia WP.

J Biol Chem. 2014 Oct 24;289(43):29751-65. doi: 10.1074/jbc.M114.565960. Epub 2014 Aug 28.

3.

The unfolded protein response sensor IRE1alpha is required at 2 distinct steps in B cell lymphopoiesis.

Zhang K, Wong HN, Song B, Miller CN, Scheuner D, Kaufman RJ.

J Clin Invest. 2005 Feb;115(2):268-81.

4.

Measurement of ER stress response and inflammation in the mouse model of nonalcoholic fatty liver disease.

Zheng Z, Zhang C, Zhang K.

Methods Enzymol. 2011;489:329-48. doi: 10.1016/B978-0-12-385116-1.00019-4.

PMID:
21266239
5.

Proapoptotic BAX and BAK modulate the unfolded protein response by a direct interaction with IRE1alpha.

Hetz C, Bernasconi P, Fisher J, Lee AH, Bassik MC, Antonsson B, Brandt GS, Iwakoshi NN, Schinzel A, Glimcher LH, Korsmeyer SJ.

Science. 2006 Apr 28;312(5773):572-6.

6.

The endoplasmic reticulum stress sensor IRE1α protects cells from apoptosis induced by the coronavirus infectious bronchitis virus.

Fung TS, Liao Y, Liu DX.

J Virol. 2014 Nov;88(21):12752-64. doi: 10.1128/JVI.02138-14. Epub 2014 Aug 20.

7.

Endoplasmic reticulum stress in liver disease.

Malhi H, Kaufman RJ.

J Hepatol. 2011 Apr;54(4):795-809. doi: 10.1016/j.jhep.2010.11.005. Epub 2010 Nov 13. Review.

8.

Interplay between the oxidoreductase PDIA6 and microRNA-322 controls the response to disrupted endoplasmic reticulum calcium homeostasis.

Groenendyk J, Peng Z, Dudek E, Fan X, Mizianty MJ, Dufey E, Urra H, Sepulveda D, Rojas-Rivera D, Lim Y, Kim DH, Baretta K, Srikanth S, Gwack Y, Ahnn J, Kaufman RJ, Lee SK, Hetz C, Kurgan L, Michalak M.

Sci Signal. 2014 Jun 10;7(329):ra54. doi: 10.1126/scisignal.2004983.

9.

IRE1α is an endogenous substrate of endoplasmic-reticulum-associated degradation.

Sun S, Shi G, Sha H, Ji Y, Han X, Shu X, Ma H, Inoue T, Gao B, Kim H, Bu P, Guber RD, Shen X, Lee AH, Iwawaki T, Paton AW, Paton JC, Fang D, Tsai B, Yates JR 3rd, Wu H, Kersten S, Long Q, Duhamel GE, Simpson KW, Qi L.

Nat Cell Biol. 2015 Dec;17(12):1546-55. doi: 10.1038/ncb3266. Epub 2015 Nov 9.

10.

ER stress and the decline and fall of pancreatic beta cells in type 1 diabetes.

Brozzi F, Eizirik DL.

Ups J Med Sci. 2016 May;121(2):133-9. doi: 10.3109/03009734.2015.1135217. Epub 2016 Feb 22. Review.

11.

Molecular signal networks and regulating mechanisms of the unfolded protein response.

Gong J, Wang XZ, Wang T, Chen JJ, Xie XY, Hu H, Yu F, Liu HL, Jiang XY, Fan HD.

J Zhejiang Univ Sci B. 2017 Jan.;18(1):1-14. doi: 10.1631/jzus.B1600043. Review.

12.

IRE1α-XBP1s induces PDI expression to increase MTP activity for hepatic VLDL assembly and lipid homeostasis.

Wang S, Chen Z, Lam V, Han J, Hassler J, Finck BN, Davidson NO, Kaufman RJ.

Cell Metab. 2012 Oct 3;16(4):473-86. doi: 10.1016/j.cmet.2012.09.003.

13.

Dissociation of inositol-requiring enzyme (IRE1α)-mediated c-Jun N-terminal kinase activation from hepatic insulin resistance in conditional X-box-binding protein-1 (XBP1) knock-out mice.

Jurczak MJ, Lee AH, Jornayvaz FR, Lee HY, Birkenfeld AL, Guigni BA, Kahn M, Samuel VT, Glimcher LH, Shulman GI.

J Biol Chem. 2012 Jan 20;287(4):2558-67. doi: 10.1074/jbc.M111.316760. Epub 2011 Nov 28.

14.

Fortilin binds IRE1α and prevents ER stress from signaling apoptotic cell death.

Pinkaew D, Chattopadhyay A, King MD, Chunhacha P, Liu Z, Stevenson HL, Chen Y, Sinthujaroen P, McDougal OM, Fujise K.

Nat Commun. 2017 May 26;8(1):18. doi: 10.1038/s41467-017-00029-1.

15.

PARP16 is a tail-anchored endoplasmic reticulum protein required for the PERK- and IRE1α-mediated unfolded protein response.

Jwa M, Chang P.

Nat Cell Biol. 2012 Nov;14(11):1223-30. doi: 10.1038/ncb2593. Epub 2012 Oct 28. Erratum in: Nat Cell Biol. 2013 Jan;15(1):123.

16.

Phenformin activates the unfolded protein response in an AMP-activated protein kinase (AMPK)-dependent manner.

Yang L, Sha H, Davisson RL, Qi L.

J Biol Chem. 2013 May 10;288(19):13631-8. doi: 10.1074/jbc.M113.462762. Epub 2013 Apr 2.

17.

Experimental approaches for elucidation of stress-sensing mechanisms of the IRE1 family proteins.

Oikawa D, Kimata Y.

Methods Enzymol. 2011;490:195-216. doi: 10.1016/B978-0-12-385114-7.00012-X.

PMID:
21266252
18.

Measurement of the unfolded protein response to investigate its role in adipogenesis and obesity.

Han J, Kaufman RJ.

Methods Enzymol. 2014;538:135-50. doi: 10.1016/B978-0-12-800280-3.00008-6.

PMID:
24529437
19.

METABOLISM. S-Nitrosylation links obesity-associated inflammation to endoplasmic reticulum dysfunction.

Yang L, Calay ES, Fan J, Arduini A, Kunz RC, Gygi SP, Yalcin A, Fu S, Hotamisligil GS.

Science. 2015 Jul 31;349(6247):500-6. doi: 10.1126/science.aaa0079.

20.

CREB is activated by ER stress and modulates the unfolded protein response by regulating the expression of IRE1α and PERK.

Kikuchi D, Tanimoto K, Nakayama K.

Biochem Biophys Res Commun. 2016 Jan 8;469(2):243-50. doi: 10.1016/j.bbrc.2015.11.113. Epub 2015 Nov 28.

PMID:
26642955

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