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Items: 1 to 20 of 102

1.

Synaptic dysbindin-1 reductions in schizophrenia occur in an isoform-specific manner indicating their subsynaptic location.

Talbot K, Louneva N, Cohen JW, Kazi H, Blake DJ, Arnold SE.

PLoS One. 2011 Mar 1;6(3):e16886. doi: 10.1371/journal.pone.0016886.

2.

Dysbindin-1 in dorsolateral prefrontal cortex of schizophrenia cases is reduced in an isoform-specific manner unrelated to dysbindin-1 mRNA expression.

Tang J, LeGros RP, Louneva N, Yeh L, Cohen JW, Hahn CG, Blake DJ, Arnold SE, Talbot K.

Hum Mol Genet. 2009 Oct 15;18(20):3851-63. doi: 10.1093/hmg/ddp329. Epub 2009 Jul 19.

3.

Reduced DTNBP1 (dysbindin-1) mRNA in the hippocampal formation of schizophrenia patients.

Weickert CS, Rothmond DA, Hyde TM, Kleinman JE, Straub RE.

Schizophr Res. 2008 Jan;98(1-3):105-10. Epub 2007 Oct 24.

4.

Dysbindin-1 is reduced in intrinsic, glutamatergic terminals of the hippocampal formation in schizophrenia.

Talbot K, Eidem WL, Tinsley CL, Benson MA, Thompson EW, Smith RJ, Hahn CG, Siegel SJ, Trojanowski JQ, Gur RE, Blake DJ, Arnold SE.

J Clin Invest. 2004 May;113(9):1353-63.

5.

Dysbindin-1 is a synaptic and microtubular protein that binds brain snapin.

Talbot K, Cho DS, Ong WY, Benson MA, Han LY, Kazi HA, Kamins J, Hahn CG, Blake DJ, Arnold SE.

Hum Mol Genet. 2006 Oct 15;15(20):3041-54. Epub 2006 Sep 15.

PMID:
16980328
6.

Dysbindin-1, a schizophrenia-related protein, interacts with HDAC3.

Soma M, Wang M, Suo S, Ishiura S.

Neurosci Lett. 2014 Oct 17;582:120-4. doi: 10.1016/j.neulet.2014.08.046. Epub 2014 Sep 6.

PMID:
25196196
7.

Dysbindin-1C is required for the survival of hilar mossy cells and the maturation of adult newborn neurons in dentate gyrus.

Wang H, Yuan Y, Zhang Z, Yan H, Feng Y, Li W.

J Biol Chem. 2014 Oct 17;289(42):29060-72. doi: 10.1074/jbc.M114.590927. Epub 2014 Aug 25.

8.

Impaired autophagy in hilar mossy cells of the dentate gyrus and its implication in schizophrenia.

Yuan Y, Wang H, Wei Z, Li W.

J Genet Genomics. 2015 Jan 20;42(1):1-8. doi: 10.1016/j.jgg.2014.12.001. Epub 2014 Dec 23.

PMID:
25619597
9.

Increased dysbindin-1B isoform expression in schizophrenia and its propensity in aggresome formation.

Xu Y, Sun Y, Ye H, Zhu L, Liu J, Wu X, Wang L, He T, Shen Y, Wu JY, Xu Q.

Cell Discov. 2015 Nov 10;1:15032. doi: 10.1038/celldisc.2015.32. eCollection 2015.

10.

Human dysbindin (DTNBP1) gene expression in normal brain and in schizophrenic prefrontal cortex and midbrain.

Weickert CS, Straub RE, McClintock BW, Matsumoto M, Hashimoto R, Hyde TM, Herman MM, Weinberger DR, Kleinman JE.

Arch Gen Psychiatry. 2004 Jun;61(6):544-55.

PMID:
15184234
11.

Potential molecular mechanisms for decreased synaptic glutamate release in dysbindin-1 mutant mice.

Saggu S, Cannon TD, Jentsch JD, Lavin A.

Schizophr Res. 2013 May;146(1-3):254-63. doi: 10.1016/j.schres.2013.01.037. Epub 2013 Mar 6.

12.

Dysbindin-1 mutant mice implicate reduced fast-phasic inhibition as a final common disease mechanism in schizophrenia.

Carlson GC, Talbot K, Halene TB, Gandal MJ, Kazi HA, Schlosser L, Phung QH, Gur RE, Arnold SE, Siegel SJ.

Proc Natl Acad Sci U S A. 2011 Oct 25;108(43):E962-70. doi: 10.1073/pnas.1109625108. Epub 2011 Oct 3.

13.
14.

The pathogenic mechanism of dysbindin-1B toxic aggregation: BLOC-1 and intercellular vesicle trafficking.

Yang W, Zhu C, Shen Y, Xu Q.

Neuroscience. 2016 Oct 1;333:78-91. doi: 10.1016/j.neuroscience.2016.07.008. Epub 2016 Jul 12.

PMID:
27421225
15.

Dysbindin modulates prefrontal cortical glutamatergic circuits and working memory function in mice.

Jentsch JD, Trantham-Davidson H, Jairl C, Tinsley M, Cannon TD, Lavin A.

Neuropsychopharmacology. 2009 Nov;34(12):2601-8. doi: 10.1038/npp.2009.90. Epub 2009 Jul 29.

16.

Regulation of Brain-Derived Neurotrophic Factor Exocytosis and Gamma-Aminobutyric Acidergic Interneuron Synapse by the Schizophrenia Susceptibility Gene Dysbindin-1.

Yuan Q, Yang F, Xiao Y, Tan S, Husain N, Ren M, Hu Z, Martinowich K, Ng JS, Kim PJ, Han W, Nagata K, Weinberger DR, Je HS.

Biol Psychiatry. 2016 Aug 15;80(4):312-22. doi: 10.1016/j.biopsych.2015.08.019. Epub 2015 Aug 28.

17.

Dysbindin-1 loss compromises NMDAR-dependent synaptic plasticity and contextual fear conditioning.

Glen WB Jr, Horowitz B, Carlson GC, Cannon TD, Talbot K, Jentsch JD, Lavin A.

Hippocampus. 2014 Feb;24(2):204-13. doi: 10.1002/hipo.22215. Epub 2013 Nov 12.

18.

Dysbindin-1, WAVE2 and Abi-1 form a complex that regulates dendritic spine formation.

Ito H, Morishita R, Shinoda T, Iwamoto I, Sudo K, Okamoto K, Nagata K.

Mol Psychiatry. 2010 Oct;15(10):976-86. doi: 10.1038/mp.2010.69. Epub 2010 Jun 8.

PMID:
20531346
19.

Dysbindin-associated proteome in the p2 synaptosome fraction of mouse brain.

Han MH, Hu Z, Chen CY, Chen Y, Gucek M, Li Z, Markey SP.

J Proteome Res. 2014 Nov 7;13(11):4567-80. doi: 10.1021/pr500656z. Epub 2014 Sep 19.

20.

Dysbindin-1, a schizophrenia-related protein, functionally interacts with the DNA- dependent protein kinase complex in an isoform-dependent manner.

Oyama S, Yamakawa H, Sasagawa N, Hosoi Y, Futai E, Ishiura S.

PLoS One. 2009;4(1):e4199. doi: 10.1371/journal.pone.0004199. Epub 2009 Jan 14.

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