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Items: 1 to 20 of 112

1.

Human-specific loss of regulatory DNA and the evolution of human-specific traits.

McLean CY, Reno PL, Pollen AA, Bassan AI, Capellini TD, Guenther C, Indjeian VB, Lim X, Menke DB, Schaar BT, Wenger AM, Bejerano G, Kingsley DM.

Nature. 2011 Mar 10;471(7337):216-9. doi: 10.1038/nature09774.

2.

A penile spine/vibrissa enhancer sequence is missing in modern and extinct humans but is retained in multiple primates with penile spines and sensory vibrissae.

Reno PL, McLean CY, Hines JE, Capellini TD, Bejerano G, Kingsley DM.

PLoS One. 2013 Dec 19;8(12):e84258. doi: 10.1371/journal.pone.0084258. eCollection 2013.

3.

Many human accelerated regions are developmental enhancers.

Capra JA, Erwin GD, McKinsey G, Rubenstein JL, Pollard KS.

Philos Trans R Soc Lond B Biol Sci. 2013 Nov 11;368(1632):20130025. doi: 10.1098/rstb.2013.0025. Print 2013 Dec 19.

4.

Accelerated evolution of conserved noncoding sequences in humans.

Prabhakar S, Noonan JP, Pääbo S, Rubin EM.

Science. 2006 Nov 3;314(5800):786.

5.
6.

Noncoding sequences conserved in a limited number of mammals in the SIM2 interval are frequently functional.

Frazer KA, Tao H, Osoegawa K, de Jong PJ, Chen X, Doherty MF, Cox DR.

Genome Res. 2004 Mar;14(3):367-72. Epub 2004 Feb 12.

7.

Hundreds of conserved non-coding genomic regions are independently lost in mammals.

Hiller M, Schaar BT, Bejerano G.

Nucleic Acids Res. 2012 Dec;40(22):11463-76. doi: 10.1093/nar/gks905. Epub 2012 Oct 5.

8.

Detection of weakly conserved ancestral mammalian regulatory sequences by primate comparisons.

Wang QF, Prabhakar S, Chanan S, Cheng JF, Rubin EM, Boffelli D.

Genome Biol. 2007;8(1):R1.

9.

Close sequence comparisons are sufficient to identify human cis-regulatory elements.

Prabhakar S, Poulin F, Shoukry M, Afzal V, Rubin EM, Couronne O, Pennacchio LA.

Genome Res. 2006 Jul;16(7):855-63. Epub 2006 Jun 12.

10.
11.

Cis-regulatory elements: molecular mechanisms and evolutionary processes underlying divergence.

Wittkopp PJ, Kalay G.

Nat Rev Genet. 2011 Dec 6;13(1):59-69. doi: 10.1038/nrg3095. Review.

PMID:
22143240
12.

Structural divergence between the human and chimpanzee genomes.

Kehrer-Sawatzki H, Cooper DN.

Hum Genet. 2007 Feb;120(6):759-78. Epub 2006 Oct 26. Review.

PMID:
17066299
13.

Parallel patterns of evolution in the genomes and transcriptomes of humans and chimpanzees.

Khaitovich P, Hellmann I, Enard W, Nowick K, Leinweber M, Franz H, Weiss G, Lachmann M, Pääbo S.

Science. 2005 Sep 16;309(5742):1850-4. Epub 2005 Sep 1.

14.

Fast-evolving noncoding sequences in the human genome.

Bird CP, Stranger BE, Liu M, Thomas DJ, Ingle CE, Beazley C, Miller W, Hurles ME, Dermitzakis ET.

Genome Biol. 2007;8(6):R118.

15.

Human-chimpanzee differences in a FZD8 enhancer alter cell-cycle dynamics in the developing neocortex.

Boyd JL, Skove SL, Rouanet JP, Pilaz LJ, Bepler T, Gordân R, Wray GA, Silver DL.

Curr Biol. 2015 Mar 16;25(6):772-9. doi: 10.1016/j.cub.2015.01.041. Epub 2015 Feb 19.

16.

"Reverse Genomics" Predicts Function of Human Conserved Noncoding Elements.

Marcovitz A, Jia R, Bejerano G.

Mol Biol Evol. 2016 May;33(5):1358-69. doi: 10.1093/molbev/msw001. Epub 2016 Jan 6.

17.

Exploring the genesis and functions of Human Accelerated Regions sheds light on their role in human evolution.

Hubisz MJ, Pollard KS.

Curr Opin Genet Dev. 2014 Dec;29:15-21. doi: 10.1016/j.gde.2014.07.005. Epub 2014 Aug 23. Review.

18.

Imprinted genes show unique patterns of sequence conservation.

Hutter B, Bieg M, Helms V, Paulsen M.

BMC Genomics. 2010 Nov 22;11:649. doi: 10.1186/1471-2164-11-649.

19.

Non-random genomic divergence in repetitive sequences of human and chimpanzee in genes of different functional categories.

Shankar R, Chaurasia A, Ghosh B, Chekmenev D, Cheremushkin E, Kel A, Mukerji M.

Mol Genet Genomics. 2007 Apr;277(4):441-55. Epub 2007 Mar 9.

PMID:
17375324
20.

Conserved and non-conserved enhancers direct tissue specific transcription in ancient germ layer specific developmental control genes.

Chatterjee S, Bourque G, Lufkin T.

BMC Dev Biol. 2011 Oct 20;11:63. doi: 10.1186/1471-213X-11-63.

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