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Items: 1 to 20 of 100

1.

Cancer. New epigenetic drivers of cancers.

Elsässer SJ, Allis CD, Lewis PW.

Science. 2011 Mar 4;331(6021):1145-6. doi: 10.1126/science.1203280. No abstract available.

PMID:
21385704
2.

DAXX/ATRX, MEN1, and mTOR pathway genes are frequently altered in pancreatic neuroendocrine tumors.

Jiao Y, Shi C, Edil BH, de Wilde RF, Klimstra DS, Maitra A, Schulick RD, Tang LH, Wolfgang CL, Choti MA, Velculescu VE, Diaz LA Jr, Vogelstein B, Kinzler KW, Hruban RH, Papadopoulos N.

Science. 2011 Mar 4;331(6021):1199-203. doi: 10.1126/science.1200609. Epub 2011 Jan 20.

3.

Epigenetic dysregulation and poorer prognosis in DAXX-deficient pancreatic neuroendocrine tumours.

Pipinikas CP, Dibra H, Karpathakis A, Feber A, Novelli M, Oukrif D, Fusai G, Valente R, Caplin M, Meyer T, Teschendorff A, Bell C, Morris TJ, Salomoni P, Luong TV, Davidson B, Beck S, Thirlwell C.

Endocr Relat Cancer. 2015 Jun;22(3):L13-8. doi: 10.1530/ERC-15-0108. Epub 2015 Apr 21. No abstract available.

4.

Current understanding of the molecular biology of pancreatic neuroendocrine tumors.

Zhang J, Francois R, Iyer R, Seshadri M, Zajac-Kaye M, Hochwald SN.

J Natl Cancer Inst. 2013 Jul 17;105(14):1005-17. doi: 10.1093/jnci/djt135. Epub 2013 Jul 9. Review.

PMID:
23840053
5.

Molecular pathogenesis and targeted therapy of sporadic pancreatic neuroendocrine tumors.

Capurso G, Archibugi L, Delle Fave G.

J Hepatobiliary Pancreat Sci. 2015 Aug;22(8):594-601. doi: 10.1002/jhbp.210. Epub 2015 Jan 25. Review.

PMID:
25619712
6.

Ileal neuroendocrine tumors show elevated activation of mammalian target of rapamycin complex.

Geis C, Fendrich V, Rexin P, Di Fazio P, Bartsch DK, Ocker M, Quint K, Heverhagen AE.

J Surg Res. 2015 Apr;194(2):388-93. doi: 10.1016/j.jss.2014.10.052. Epub 2014 Nov 5.

PMID:
25439321
7.

KRAS and DAXX/ATRX gene mutations are correlated with the clinicopathological features, advanced diseases, and poor prognosis in Chinese patients with pancreatic neuroendocrine tumors.

Yuan F, Shi M, Ji J, Shi H, Zhou C, Yu Y, Liu B, Zhu Z, Zhang J.

Int J Biol Sci. 2014 Aug 30;10(9):957-65. doi: 10.7150/ijbs.9773. eCollection 2014.

8.

The genetics of neuroendocrine tumors.

Öberg K.

Semin Oncol. 2013 Feb;40(1):37-44. doi: 10.1053/j.seminoncol.2012.11.005.

PMID:
23391111
9.

Altered telomeres in tumors with ATRX and DAXX mutations.

Heaphy CM, de Wilde RF, Jiao Y, Klein AP, Edil BH, Shi C, Bettegowda C, Rodriguez FJ, Eberhart CG, Hebbar S, Offerhaus GJ, McLendon R, Rasheed BA, He Y, Yan H, Bigner DD, Oba-Shinjo SM, Marie SK, Riggins GJ, Kinzler KW, Vogelstein B, Hruban RH, Maitra A, Papadopoulos N, Meeker AK.

Science. 2011 Jul 22;333(6041):425. doi: 10.1126/science.1207313. Epub 2011 Jun 30.

10.

Detection of Somatic Mutations in Gastroenteropancreatic Neuroendocrine Tumors Using Targeted Deep Sequencing.

Backman S, Norlén O, Eriksson B, Skogseid B, Stålberg P, Crona J.

Anticancer Res. 2017 Feb;37(2):705-712.

PMID:
28179320
11.

Analysis of molecular pathways in sporadic neuroendocrine tumors of the gastro-entero-pancreatic system.

Arnold CN, Sosnowski A, Schmitt-Gräff A, Arnold R, Blum HE.

Int J Cancer. 2007 May 15;120(10):2157-64.

12.

Loss of ATRX, genome instability, and an altered DNA damage response are hallmarks of the alternative lengthening of telomeres pathway.

Lovejoy CA, Li W, Reisenweber S, Thongthip S, Bruno J, de Lange T, De S, Petrini JH, Sung PA, Jasin M, Rosenbluh J, Zwang Y, Weir BA, Hatton C, Ivanova E, Macconaill L, Hanna M, Hahn WC, Lue NF, Reddel RR, Jiao Y, Kinzler K, Vogelstein B, Papadopoulos N, Meeker AK; ALT Starr Cancer Consortium.

PLoS Genet. 2012;8(7):e1002772. Epub 2012 Jul 19.

13.

Releasing the brakes on a chromatin-remodeling enzyme.

Manning BJ, Peterson CL.

Nat Struct Mol Biol. 2013 Jan;20(1):5-7. doi: 10.1038/nsmb.2482.

PMID:
23288358
14.

Loss of DAXX and ATRX are associated with chromosome instability and reduced survival of patients with pancreatic neuroendocrine tumors.

Marinoni I, Kurrer AS, Vassella E, Dettmer M, Rudolph T, Banz V, Hunger F, Pasquinelli S, Speel EJ, Perren A.

Gastroenterology. 2014 Feb;146(2):453-60.e5. doi: 10.1053/j.gastro.2013.10.020. Epub 2013 Oct 19.

PMID:
24148618
15.

Role of nucleosomal occupancy in the epigenetic silencing of the MLH1 CpG island.

Lin JC, Jeong S, Liang G, Takai D, Fatemi M, Tsai YC, Egger G, Gal-Yam EN, Jones PA.

Cancer Cell. 2007 Nov;12(5):432-44.

16.

PHLDA3 is a novel tumor suppressor of pancreatic neuroendocrine tumors.

Ohki R, Saito K, Chen Y, Kawase T, Hiraoka N, Saigawa R, Minegishi M, Aita Y, Yanai G, Shimizu H, Yachida S, Sakata N, Doi R, Kosuge T, Shimada K, Tycko B, Tsukada T, Kanai Y, Sumi S, Namiki H, Taya Y, Shibata T, Nakagama H.

Proc Natl Acad Sci U S A. 2014 Jun 10;111(23):E2404-13. doi: 10.1073/pnas.1319962111. Epub 2014 May 27.

17.

Genes involved in angiogenesis and mTOR pathways are frequently mutated in Asian patients with pancreatic neuroendocrine tumors.

Chou WC, Lin PH, Yeh YC, Shyr YM, Fang WL, Wang SE, Liu CY, Chang PM, Chen MH, Hung YP, Li CP, Chao Y, Chen MH.

Int J Biol Sci. 2016 Nov 25;12(12):1523-1532. eCollection 2016.

18.

Aberrant Menin expression is an early event in pancreatic neuroendocrine tumorigenesis.

Hackeng WM, Brosens LA, Poruk KE, Noë M, Hosoda W, Poling JS, Rizzo A, Campbell-Thompson M, Atkinson MA, Konukiewitz B, Klöppel G, Heaphy CM, Meeker AK, Wood LD.

Hum Pathol. 2016 Oct;56:93-100. doi: 10.1016/j.humpath.2016.06.006. Epub 2016 Jun 21.

PMID:
27342911
19.

Histone variants in pluripotency and disease.

Skene PJ, Henikoff S.

Development. 2013 Jun;140(12):2513-24. doi: 10.1242/dev.091439. Review.

20.

Epigenetic response to environmental stress: Assembly of BRG1-G9a/GLP-DNMT3 repressive chromatin complex on Myh6 promoter in pathologically stressed hearts.

Han P, Li W, Yang J, Shang C, Lin CH, Cheng W, Hang CT, Cheng HL, Chen CH, Wong J, Xiong Y, Zhao M, Drakos SG, Ghetti A, Li DY, Bernstein D, Chen HS, Quertermous T, Chang CP.

Biochim Biophys Acta. 2016 Jul;1863(7 Pt B):1772-81. doi: 10.1016/j.bbamcr.2016.03.002. Epub 2016 Mar 4.

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