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Items: 1 to 20 of 88

1.

Nuclear but not cytosolic phosphoinositide 3-kinase beta has an essential function in cell survival.

Kumar A, Redondo-Muñoz J, Perez-García V, Cortes I, Chagoyen M, Carrera AC.

Mol Cell Biol. 2011 May;31(10):2122-33. doi: 10.1128/MCB.01313-10. Epub 2011 Mar 7.

2.

Phosphoinositide 3-kinase β regulates chromosome segregation in mitosis.

Silió V, Redondo-Muñoz J, Carrera AC.

Mol Biol Cell. 2012 Dec;23(23):4526-42. doi: 10.1091/mbc.E12-05-0371. Epub 2012 Oct 10.

3.

A biochemical mechanism for the oncogenic potential of the p110beta catalytic subunit of phosphoinositide 3-kinase.

Dbouk HA, Pang H, Fiser A, Backer JM.

Proc Natl Acad Sci U S A. 2010 Nov 16;107(46):19897-902. doi: 10.1073/pnas.1008739107. Epub 2010 Oct 28.

4.

Class IA phosphoinositide 3-kinases are obligate p85-p110 heterodimers.

Geering B, Cutillas PR, Nock G, Gharbi SI, Vanhaesebroeck B.

Proc Natl Acad Sci U S A. 2007 May 8;104(19):7809-14. Epub 2007 Apr 30.

5.

Dynamics of GFP-Fusion p110α and p110β Isoforms of PI3K Signaling Pathway in Normal and Cancer Cells.

Singh P, Dar MS, Singh G, Jamwal G, Sharma PR, Ahmad M, Dar MJ.

J Cell Biochem. 2016 Dec;117(12):2864-2874. doi: 10.1002/jcb.25598. Epub 2016 Jun 3.

PMID:
27167447
6.

Cell activation-induced phosphoinositide 3-kinase alpha/beta dimerization regulates PTEN activity.

Pérez-García V, Redondo-Muñoz J, Kumar A, Carrera AC.

Mol Cell Biol. 2014 Sep 15;34(18):3359-73. doi: 10.1128/MCB.00167-14. Epub 2014 Jun 23.

7.

p110α and p110β isoforms of PI3K signaling: are they two sides of the same coin?

Singh P, Dar MS, Dar MJ.

FEBS Lett. 2016 Sep;590(18):3071-82. doi: 10.1002/1873-3468.12377. Epub 2016 Sep 12. Review.

8.

Class IA Phosphatidylinositol 3-Kinase Isoform p110α Mediates Vascular Remodeling.

Vantler M, Jesus J, Leppänen O, Scherner M, Berghausen EM, Mustafov L, Chen X, Kramer T, Zierden M, Gerhardt M, Ten Freyhaus H, Blaschke F, Sterner-Kock A, Baldus S, Zhao JJ, Rosenkranz S.

Arterioscler Thromb Vasc Biol. 2015 Jun;35(6):1434-44. doi: 10.1161/ATVBAHA.114.304887. Epub 2015 Apr 23.

9.

Specific function of phosphoinositide 3-kinase beta in the control of DNA replication.

Marqués M, Kumar A, Poveda AM, Zuluaga S, Hernández C, Jackson S, Pasero P, Carrera AC.

Proc Natl Acad Sci U S A. 2009 May 5;106(18):7525-30. doi: 10.1073/pnas.0812000106. Epub 2009 Apr 22.

10.

Distinct and opposing roles for the phosphatidylinositol 3-OH kinase catalytic subunits p110α and p110β in the regulation of insulin secretion from rodent and human beta cells.

Kolic J, Spigelman AF, Plummer G, Leung E, Hajmrle C, Kin T, Shapiro AM, Manning Fox JE, MacDonald PE.

Diabetologia. 2013 Jun;56(6):1339-49. doi: 10.1007/s00125-013-2882-4. Epub 2013 Apr 9.

PMID:
23568272
11.

The oncogenic properties of mutant p110alpha and p110beta phosphatidylinositol 3-kinases in human mammary epithelial cells.

Zhao JJ, Liu Z, Wang L, Shin E, Loda MF, Roberts TM.

Proc Natl Acad Sci U S A. 2005 Dec 20;102(51):18443-8. Epub 2005 Dec 8.

12.

Characterization of a tumor-associated activating mutation of the p110β PI 3-kinase.

Dbouk HA, Khalil BD, Wu H, Shymanets A, Nürnberg B, Backer JM.

PLoS One. 2013 May 29;8(5):e63833. doi: 10.1371/journal.pone.0063833. Print 2013.

14.

Phosphoinositide 3-kinases p110alpha and p110beta regulate cell cycle entry, exhibiting distinct activation kinetics in G1 phase.

Marqués M, Kumar A, Cortés I, Gonzalez-García A, Hernández C, Moreno-Ortiz MC, Carrera AC.

Mol Cell Biol. 2008 Apr;28(8):2803-14. doi: 10.1128/MCB.01786-07. Epub 2008 Feb 19.

15.

The role of PI 3-kinase p110beta in AKT signally, cell survival, and proliferation in human prostate cancer cells.

Hill KM, Kalifa S, Das JR, Bhatti T, Gay M, Williams D, Taliferro-Smith L, De Marzo AM.

Prostate. 2010 May 15;70(7):755-64. doi: 10.1002/pros.21108.

PMID:
20058239
16.

Membrane localization of all class I PI 3-kinase isoforms suppresses c-Myc-induced apoptosis in Rat1 fibroblasts via Akt.

Link W, Rosado A, Fominaya J, Thomas JE, Carnero A.

J Cell Biochem. 2005 Aug 1;95(5):979-89.

PMID:
15838873
17.

p110beta is up-regulated during differentiation of 3T3-L1 cells and contributes to the highly insulin-responsive glucose transport activity.

Asano T, Kanda A, Katagiri H, Nawano M, Ogihara T, Inukai K, Anai M, Fukushima Y, Yazaki Y, Kikuchi M, Hooshmand-Rad R, Heldin CH, Oka Y, Funaki M.

J Biol Chem. 2000 Jun 9;275(23):17671-6.

18.

The p110beta isoform of phosphoinositide 3-kinase signals downstream of G protein-coupled receptors and is functionally redundant with p110gamma.

Guillermet-Guibert J, Bjorklof K, Salpekar A, Gonella C, Ramadani F, Bilancio A, Meek S, Smith AJ, Okkenhaug K, Vanhaesebroeck B.

Proc Natl Acad Sci U S A. 2008 Jun 17;105(24):8292-7. doi: 10.1073/pnas.0707761105. Epub 2008 Jun 10.

19.

Nuclear import and export signals enable rapid nucleocytoplasmic shuttling of the atypical protein kinase C lambda.

Perander M, Bjorkoy G, Johansen T.

J Biol Chem. 2001 Apr 20;276(16):13015-24. Epub 2000 Dec 13.

20.

Posttranscriptional regulation of the p85α adapter subunit of phosphatidylinositol 3-kinase in human leukemia cells.

Hofmann BT, Hoxha E, Mohr E, Schulz K, Jücker M.

Leuk Lymphoma. 2011 Mar;52(3):467-77. doi: 10.3109/10428194.2010.530360. Epub 2010 Nov 15.

PMID:
21077741

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