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Items: 1 to 20 of 101

1.

Hcrtr1 and 2 signaling differentially regulates depression-like behaviors.

Scott MM, Marcus JN, Pettersen A, Birnbaum SG, Mochizuki T, Scammell TE, Nestler EJ, Elmquist JK, Lutter M.

Behav Brain Res. 2011 Sep 23;222(2):289-94. doi: 10.1016/j.bbr.2011.02.044. Epub 2011 Mar 4.

2.

Nicotine self-administration in the rat: effects of hypocretin antagonists and changes in hypocretin mRNA.

LeSage MG, Perry JL, Kotz CM, Shelley D, Corrigall WA.

Psychopharmacology (Berl). 2010 Apr;209(2):203-12. doi: 10.1007/s00213-010-1792-0. Epub 2010 Feb 24.

3.

Orexin-1 receptor antagonism fails to reduce anxiety-like behaviour in either plus-maze-naïve or plus-maze-experienced mice.

Rodgers RJ, Wright FL, Snow NF, Taylor LJ.

Behav Brain Res. 2013 Apr 15;243:213-9. doi: 10.1016/j.bbr.2012.12.064. Epub 2013 Jan 17.

PMID:
23333844
4.

Orexin / hypocretin 1 receptor antagonist reduces heroin self-administration and cue-induced heroin seeking.

Smith RJ, Aston-Jones G.

Eur J Neurosci. 2012 Mar;35(5):798-804. doi: 10.1111/j.1460-9568.2012.08013.x. Epub 2012 Feb 22.

5.

Dual hypocretin receptor antagonism is more effective for sleep promotion than antagonism of either receptor alone.

Morairty SR, Revel FG, Malherbe P, Moreau JL, Valladao D, Wettstein JG, Kilduff TS, Borroni E.

PLoS One. 2012;7(7):e39131. doi: 10.1371/journal.pone.0039131. Epub 2012 Jul 2.

6.

Hypocretin receptor expression in canine and murine narcolepsy models and in hypocretin-ligand deficient human narcolepsy.

Mishima K, Fujiki N, Yoshida Y, Sakurai T, Honda M, Mignot E, Nishino S.

Sleep. 2008 Aug;31(8):1119-26.

7.
8.

Genetic inactivation of the NMDA receptor NR2A subunit has anxiolytic- and antidepressant-like effects in mice.

Boyce-Rustay JM, Holmes A.

Neuropsychopharmacology. 2006 Nov;31(11):2405-14. Epub 2006 Feb 8.

9.

Antagonism of orexin 1 receptors eliminates motor hyperactivity and improves homing response acquisition in juvenile rats exposed to alcohol during early postnatal period.

Stettner GM, Kubin L, Volgin DV.

Behav Brain Res. 2011 Aug 1;221(1):324-8. doi: 10.1016/j.bbr.2011.03.028. Epub 2011 Mar 21.

10.

Orexin mediates morphine place preference, but not morphine-induced hyperactivity or sensitization.

Sharf R, Guarnieri DJ, Taylor JR, DiLeone RJ.

Brain Res. 2010 Mar 4;1317:24-32. doi: 10.1016/j.brainres.2009.12.035. Epub 2009 Dec 23.

11.

Hypocretin/orexin signaling in the hypothalamic paraventricular nucleus is essential for the expression of nicotine withdrawal.

Plaza-Zabala A, Flores Á, Maldonado R, Berrendero F.

Biol Psychiatry. 2012 Feb 1;71(3):214-23. doi: 10.1016/j.biopsych.2011.06.025. Epub 2011 Aug 10.

PMID:
21831361
12.

Activation of the orexin 1 receptor is a critical component of CO2-mediated anxiety and hypertension but not bradycardia.

Johnson PL, Samuels BC, Fitz SD, Lightman SL, Lowry CA, Shekhar A.

Neuropsychopharmacology. 2012 Jul;37(8):1911-22. doi: 10.1038/npp.2012.38. Epub 2012 Mar 28.

13.

Involvement of the orexin/hypocretin system in ethanol conditioned place preference.

Voorhees CM, Cunningham CL.

Psychopharmacology (Berl). 2011 Apr;214(4):805-18. doi: 10.1007/s00213-010-2082-6. Epub 2010 Nov 24.

14.

Chemical stimulation of the lateral hypothalamus induces conditioned place preference in rats: Involvement of OX1 and CB1 receptors in the ventral tegmental area.

Taslimi Z, Haghparast A, Hassanpour-Ezatti M, Safari MS.

Behav Brain Res. 2011 Feb 2;217(1):41-6. doi: 10.1016/j.bbr.2010.10.007. Epub 2010 Oct 19.

PMID:
20937330
15.

Orexin signaling via the orexin 1 receptor mediates operant responding for food reinforcement.

Sharf R, Sarhan M, Brayton CE, Guarnieri DJ, Taylor JR, DiLeone RJ.

Biol Psychiatry. 2010 Apr 15;67(8):753-60. doi: 10.1016/j.biopsych.2009.12.035. Epub 2010 Feb 26.

16.

Orexin A/hypocretin-1 selectively promotes motivation for positive reinforcers.

Borgland SL, Chang SJ, Bowers MS, Thompson JL, Vittoz N, Floresco SB, Chou J, Chen BT, Bonci A.

J Neurosci. 2009 Sep 9;29(36):11215-25. doi: 10.1523/JNEUROSCI.6096-08.2009.

17.

Elevated anxiety-like and depressive behavior in Desert hedgehog knockout male mice.

Umehara F, Mishima K, Egashira N, Ogata A, Iwasaki K, Fujiwara M.

Behav Brain Res. 2006 Nov 1;174(1):167-73. Epub 2006 Sep 6.

PMID:
16952407
18.

Genetic and pharmacological evidence of a role for GABA(B) receptors in the modulation of anxiety- and antidepressant-like behavior.

Mombereau C, Kaupmann K, Froestl W, Sansig G, van der Putten H, Cryan JF.

Neuropsychopharmacology. 2004 Jun;29(6):1050-62.

19.

Role of orexin receptors in the nucleus accumbens in dopamine-dependent turning behaviour of rats.

Kotani A, Ikeda H, Koshikawa N, Cools AR.

Neuropharmacology. 2008 Mar;54(3):613-9. Epub 2007 Nov 22.

PMID:
18160080
20.

The orexin-1 receptor antagonist SB-334867 decreases sympathetic responses to a moderate dose of methamphetamine and stress.

Rusyniak DE, Zaretsky DV, Zaretskaia MV, Durant PJ, DiMicco JA.

Physiol Behav. 2012 Dec 5;107(5):743-50. doi: 10.1016/j.physbeh.2012.02.010. Epub 2012 Feb 14.

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