Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 226

1.

Differential effects of sulforaphane on histone deacetylases, cell cycle arrest and apoptosis in normal prostate cells versus hyperplastic and cancerous prostate cells.

Clarke JD, Hsu A, Yu Z, Dashwood RH, Ho E.

Mol Nutr Food Res. 2011 Jul;55(7):999-1009. doi: 10.1002/mnfr.201000547. Epub 2011 Mar 4.

2.

Sulforaphane inhibits histone deacetylase activity in BPH-1, LnCaP and PC-3 prostate epithelial cells.

Myzak MC, Hardin K, Wang R, Dashwood RH, Ho E.

Carcinogenesis. 2006 Apr;27(4):811-9. Epub 2005 Nov 9.

3.

Histone deacetylase turnover and recovery in sulforaphane-treated colon cancer cells: competing actions of 14-3-3 and Pin1 in HDAC3/SMRT corepressor complex dissociation/reassembly.

Rajendran P, Delage B, Dashwood WM, Yu TW, Wuth B, Williams DE, Ho E, Dashwood RH.

Mol Cancer. 2011 May 30;10:68. doi: 10.1186/1476-4598-10-68.

4.

A novel mechanism of chemoprotection by sulforaphane: inhibition of histone deacetylase.

Myzak MC, Karplus PA, Chung FL, Dashwood RH.

Cancer Res. 2004 Aug 15;64(16):5767-74.

5.

Induction of p21 protein protects against sulforaphane-induced mitotic arrest in LNCaP human prostate cancer cell line.

Herman-Antosiewicz A, Xiao H, Lew KL, Singh SV.

Mol Cancer Ther. 2007 May;6(5):1673-81.

6.

Dietary sulforaphane, a histone deacetylase inhibitor for cancer prevention.

Ho E, Clarke JD, Dashwood RH.

J Nutr. 2009 Dec;139(12):2393-6. doi: 10.3945/jn.109.113332. Epub 2009 Oct 7.

7.

Targeting cell cycle machinery as a molecular mechanism of sulforaphane in prostate cancer prevention.

Wang L, Liu D, Ahmed T, Chung FL, Conaway C, Chiao JW.

Int J Oncol. 2004 Jan;24(1):187-92.

PMID:
14654956
8.

Involvement of c-Jun N-terminal kinase in G2/M arrest and caspase-mediated apoptosis induced by sulforaphane in DU145 prostate cancer cells.

Cho SD, Li G, Hu H, Jiang C, Kang KS, Lee YS, Kim SH, Lu J.

Nutr Cancer. 2005;52(2):213-24.

PMID:
16201852
9.

Multi-targeted prevention of cancer by sulforaphane.

Clarke JD, Dashwood RH, Ho E.

Cancer Lett. 2008 Oct 8;269(2):291-304. doi: 10.1016/j.canlet.2008.04.018. Epub 2008 May 27. Review.

10.

Sulforaphane and its metabolite mediate growth arrest and apoptosis in human prostate cancer cells.

Chiao JW, Chung FL, Kancherla R, Ahmed T, Mittelman A, Conaway CC.

Int J Oncol. 2002 Mar;20(3):631-6.

PMID:
11836580
11.

Green tea polyphenols causes cell cycle arrest and apoptosis in prostate cancer cells by suppressing class I histone deacetylases.

Thakur VS, Gupta K, Gupta S.

Carcinogenesis. 2012 Feb;33(2):377-84. doi: 10.1093/carcin/bgr277. Epub 2011 Nov 23.

12.

Modulation of histone deacetylase activity by dietary isothiocyanates and allyl sulfides: studies with sulforaphane and garlic organosulfur compounds.

Nian H, Delage B, Ho E, Dashwood RH.

Environ Mol Mutagen. 2009 Apr;50(3):213-21. doi: 10.1002/em.20454. Review.

13.

Sulforaphane suppresses in vitro and in vivo lung tumorigenesis through downregulation of HDAC activity.

Jiang LL, Zhou SJ, Zhang XM, Chen HQ, Liu W.

Biomed Pharmacother. 2016 Mar;78:74-80. doi: 10.1016/j.biopha.2015.11.007. Epub 2016 Jan 14.

PMID:
26898427
14.

3,3'-Diindolylmethane, but not indole-3-carbinol, inhibits histone deacetylase activity in prostate cancer cells.

Beaver LM, Yu TW, Sokolowski EI, Williams DE, Dashwood RH, Ho E.

Toxicol Appl Pharmacol. 2012 Sep 15;263(3):345-51. doi: 10.1016/j.taap.2012.07.007. Epub 2012 Jul 16.

15.

Sulforaphane modulates telomerase activity via epigenetic regulation in prostate cancer cell lines.

Abbas A, Hall JA, Patterson WL 3rd, Ho E, Hsu A, Al-Mulla F, Georgel PT.

Biochem Cell Biol. 2016 Feb;94(1):71-81. doi: 10.1139/bcb-2015-0038. Epub 2015 Sep 9.

PMID:
26458818
16.

De-repression of the p21 promoter in prostate cancer cells by an isothiocyanate via inhibition of HDACs and c-Myc.

Wang LG, Liu XM, Fang Y, Dai W, Chiao FB, Puccio GM, Feng J, Liu D, Chiao JW.

Int J Oncol. 2008 Aug;33(2):375-80.

PMID:
18636159
17.

Effects of sulforaphane and 3,3'-diindolylmethane on genome-wide promoter methylation in normal prostate epithelial cells and prostate cancer cells.

Wong CP, Hsu A, Buchanan A, Palomera-Sanchez Z, Beaver LM, Houseman EA, Williams DE, Dashwood RH, Ho E.

PLoS One. 2014 Jan 22;9(1):e86787. doi: 10.1371/journal.pone.0086787. eCollection 2014.

18.

Epigenetic mechanism of growth inhibition induced by phenylhexyl isothiocyanate in prostate cancer cells.

Beklemisheva AA, Fang Y, Feng J, Ma X, Dai W, Chiao JW.

Anticancer Res. 2006 Mar-Apr;26(2A):1225-30.

19.

The effect of sulforaphane on histone deacetylase activity in keratinocytes: Differences between in vitro and in vivo analyses.

Dickinson SE, Rusche JJ, Bec SL, Horn DJ, Janda J, Rim SH, Smith CL, Bowden GT.

Mol Carcinog. 2015 Nov;54(11):1513-20. doi: 10.1002/mc.22224. Epub 2014 Oct 12. Erratum in: Mol Carcinog. 2016 Jul;55(7):1210.

20.

A novel histone deacetylase (HDAC) inhibitor MHY219 induces apoptosis via up-regulation of androgen receptor expression in human prostate cancer cells.

Patra N, De U, Kim TH, Lee YJ, Ahn MY, Kim ND, Yoon JH, Choi WS, Moon HR, Lee BM, Kim HS.

Biomed Pharmacother. 2013 Jun;67(5):407-15. doi: 10.1016/j.biopha.2013.01.006. Epub 2013 Feb 16.

PMID:
23583193

Supplemental Content

Support Center