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Amino acid changes within the E protein hinge region that affect dengue virus type 2 infectivity and fusion.

Butrapet S, Childers T, Moss KJ, Erb SM, Luy BE, Calvert AE, Blair CD, Roehrig JT, Huang CY.

Virology. 2011 Apr 25;413(1):118-27. doi: 10.1016/j.virol.2011.01.030. Epub 2011 Feb 24.


Domain-III FG loop of the dengue virus type 2 envelope protein is important for infection of mammalian cells and Aedes aegypti mosquitoes.

Erb SM, Butrapet S, Moss KJ, Luy BE, Childers T, Calvert AE, Silengo SJ, Roehrig JT, Huang CY, Blair CD.

Virology. 2010 Oct 25;406(2):328-35. doi: 10.1016/j.virol.2010.07.024. Epub 2010 Aug 13.


Glycosylation of the dengue 2 virus E protein at N67 is critical for virus growth in vitro but not for growth in intrathoracically inoculated Aedes aegypti mosquitoes.

Bryant JE, Calvert AE, Mesesan K, Crabtree MB, Volpe KE, Silengo S, Kinney RM, Huang CY, Miller BR, Roehrig JT.

Virology. 2007 Sep 30;366(2):415-23. Epub 2007 Jun 1.


Identification of amino acids in the dengue virus type 2 envelope glycoprotein critical to virus infectivity.

Kroschewski H, Sagripanti JL, Davidson AD.

J Gen Virol. 2009 Oct;90(Pt 10):2457-61. doi: 10.1099/vir.0.011486-0. Epub 2009 Jul 8.


Alterations of pr-M cleavage and virus export in pr-M junction chimeric dengue viruses.

Keelapang P, Sriburi R, Supasa S, Panyadee N, Songjaeng A, Jairungsri A, Puttikhunt C, Kasinrerk W, Malasit P, Sittisombut N.

J Virol. 2004 Mar;78(5):2367-81.


Residues in domain III of the dengue virus envelope glycoprotein involved in cell-surface glycosaminoglycan binding.

Watterson D, Kobe B, Young PR.

J Gen Virol. 2012 Jan;93(Pt 1):72-82. doi: 10.1099/vir.0.037317-0. Epub 2011 Sep 28.


E/NS1 modifications of dengue 2 virus after serial passages in mammalian and/or mosquito cells.

Chen WJ, Wu HR, Chiou SS.

Intervirology. 2003;46(5):289-95.


Determinants in the envelope E protein and viral RNA helicase NS3 that influence the induction of apoptosis in response to infection with dengue type 1 virus.

Duarte dos Santos CN, Frenkiel MP, Courageot MP, Rocha CF, Vazeille-Falcoz MC, Wien MW, Rey FA, Deubel V, Desprès P.

Virology. 2000 Sep 1;274(2):292-308.


Comparison of sequences of E/NS1 gene junction of dengue type 3 virus following culture subpassage in C6/36 cells to study the possible occurrence of mutations.

Thayan R, Morita K, Vijayamalar B, Zainah S, Chew TK, Oda K, Sinniah M, Igarashi A.

Southeast Asian J Trop Med Public Health. 1997 Jun;28(2):380-6.


Differential modulation of prM cleavage, extracellular particle distribution, and virus infectivity by conserved residues at nonfurin consensus positions of the dengue virus pr-M junction.

Junjhon J, Lausumpao M, Supasa S, Noisakran S, Songjaeng A, Saraithong P, Chaichoun K, Utaipat U, Keelapang P, Kanjanahaluethai A, Puttikhunt C, Kasinrerk W, Malasit P, Sittisombut N.

J Virol. 2008 Nov;82(21):10776-91. doi: 10.1128/JVI.01180-08. Epub 2008 Aug 20.


The dengue virus type 2 envelope protein fusion peptide is essential for membrane fusion.

Huang CY, Butrapet S, Moss KJ, Childers T, Erb SM, Calvert AE, Silengo SJ, Kinney RM, Blair CD, Roehrig JT.

Virology. 2010 Jan 20;396(2):305-15. doi: 10.1016/j.virol.2009.10.027. Epub 2009 Nov 12.


Essential role of dengue virus envelope protein N glycosylation at asparagine-67 during viral propagation.

Mondotte JA, Lozach PY, Amara A, Gamarnik AV.

J Virol. 2007 Jul;81(13):7136-48. Epub 2007 Apr 25.


Isolation and characterization of two phenotypically distinct dengue type-2 virus isolates from the same dengue hemorrhagic Fever patient.

Kinoshita H, Mathenge EG, Hung NT, Huong VT, Kumatori A, Yu F, Parquet MC, Inoue S, Matias RR, Natividad FF, Morita K, Hasebe F.

Jpn J Infect Dis. 2009 Sep;62(5):343-50.


Selection and partial characterization of dengue 2 virus mutants that induce fusion at elevated pH.

Guirakhoo F, Hunt AR, Lewis JG, Roehrig JT.

Virology. 1993 May;194(1):219-23.


The stem region of premembrane protein plays an important role in the virus surface protein rearrangement during dengue maturation.

Zhang Q, Hunke C, Yau YH, Seow V, Lee S, Tanner LB, Guan XL, Wenk MR, Fibriansah G, Chew PL, Kukkaro P, Biukovic G, Shi PY, Shochat SG, Grüber G, Lok SM.

J Biol Chem. 2012 Nov 23;287(48):40525-34. doi: 10.1074/jbc.M112.384446. Epub 2012 Oct 3.


A trade-off in replication in mosquito versus mammalian systems conferred by a point mutation in the NS4B protein of dengue virus type 4.

Hanley KA, Manlucu LR, Gilmore LE, Blaney JE Jr, Hanson CT, Murphy BR, Whitehead SS.

Virology. 2003 Jul 20;312(1):222-32.

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