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Items: 1 to 20 of 105

1.

Beta-agonist-associated reduction in RGS5 expression promotes airway smooth muscle hyper-responsiveness.

Yang Z, Cooper PR, Damera G, Mukhopadhyay I, Cho H, Kehrl JH, Panettieri RA Jr, Druey KM.

J Biol Chem. 2011 Apr 1;286(13):11444-55. doi: 10.1074/jbc.M110.212480.

2.

Loss of regulator of G protein signaling 5 promotes airway hyperresponsiveness in the absence of allergic inflammation.

Balenga NA, Jester W, Jiang M, Panettieri RA Jr, Druey KM.

J Allergy Clin Immunol. 2014 Aug;134(2):451-9. doi: 10.1016/j.jaci.2014.01.019.

3.

β2-Adrenoceptor agonist-induced RGS2 expression is a genomic mechanism of bronchoprotection that is enhanced by glucocorticoids.

Holden NS, Bell MJ, Rider CF, King EM, Gaunt DD, Leigh R, Johnson M, Siderovski DP, Heximer SP, Giembycz MA, Newton R.

Proc Natl Acad Sci U S A. 2011 Dec 6;108(49):19713-8. doi: 10.1073/pnas.1110226108.

4.

PDGF-dependent regulation of regulator of G protein signaling-5 expression and vascular smooth muscle cell functionality.

Gunaje JJ, Bahrami AJ, Schwartz SM, Daum G, Mahoney WM Jr.

Am J Physiol Cell Physiol. 2011 Aug;301(2):C478-89. doi: 10.1152/ajpcell.00348.2010.

5.

Regulator of G-Protein Signaling 5 Prevents Smooth Muscle Cell Proliferation and Attenuates Neointima Formation.

Daniel JM, Prock A, Dutzmann J, Sonnenschein K, Thum T, Bauersachs J, Sedding DG.

Arterioscler Thromb Vasc Biol. 2016 Feb;36(2):317-27. doi: 10.1161/ATVBAHA.115.305974.

PMID:
26663397
6.

Gi-coupled receptors mediate phosphorylation of CPI-17 and MLC20 via preferential activation of the PI3K/ILK pathway.

Huang J, Mahavadi S, Sriwai W, Hu W, Murthy KS.

Biochem J. 2006 May 15;396(1):193-200.

7.

Regulator of G-protein signaling-5 inhibits bronchial smooth muscle contraction in severe asthma.

Yang Z, Balenga N, Cooper PR, Damera G, Edwards R, Brightling CE, Panettieri RA Jr, Druey KM.

Am J Respir Cell Mol Biol. 2012 Jun;46(6):823-32. doi: 10.1165/rcmb.2011-0110OC.

8.

Gi-coupled γ-aminobutyric acid-B receptors cross-regulate phospholipase C and calcium in airway smooth muscle.

Mizuta K, Mizuta F, Xu D, Masaki E, Panettieri RA Jr, Emala CW.

Am J Respir Cell Mol Biol. 2011 Dec;45(6):1232-8. doi: 10.1165/rcmb.2011-0088OC.

9.

RGS5, RGS4, and RGS2 expression and aortic contractibility are dynamically co-regulated during aortic banding-induced hypertrophy.

Wang X, Adams LD, Pabón LM, Mahoney WM Jr, Beaudry D, Gunaje J, Geary RL, Deblois D, Schwartz SM.

J Mol Cell Cardiol. 2008 Mar;44(3):539-50. doi: 10.1016/j.yjmcc.2007.11.019.

PMID:
18207159
10.

Galpha13 regulates methacholine-induced contraction of bronchial smooth muscle via phosphorylation of MLC20.

Lee SJ, Lee WH, Ki SH, Kim YM, Lee SJ, Lee CH, Kim SG.

Biochem Pharmacol. 2009 May 1;77(9):1497-505. doi: 10.1016/j.bcp.2009.01.016.

PMID:
19426687
11.
12.

Active components of ginger potentiate β-agonist-induced relaxation of airway smooth muscle by modulating cytoskeletal regulatory proteins.

Townsend EA, Zhang Y, Xu C, Wakita R, Emala CW.

Am J Respir Cell Mol Biol. 2014 Jan;50(1):115-24. doi: 10.1165/rcmb.2013-0133OC.

13.

RGS2 is a primary terminator of β₂-adrenergic receptor-mediated G(i) signaling.

Chakir K, Zhu W, Tsang S, Woo AY, Yang D, Wang X, Zeng X, Rhee MH, Mende U, Koitabashi N, Takimoto E, Blumer KJ, Lakatta EG, Kass DA, Xiao RP.

J Mol Cell Cardiol. 2011 Jun;50(6):1000-7. doi: 10.1016/j.yjmcc.2011.01.015.

14.

Quercetin acutely relaxes airway smooth muscle and potentiates β-agonist-induced relaxation via dual phosphodiesterase inhibition of PLCβ and PDE4.

Townsend EA, Emala CW Sr.

Am J Physiol Lung Cell Mol Physiol. 2013 Sep;305(5):L396-403. doi: 10.1152/ajplung.00125.2013.

15.

Inhibition of the AMP-activated protein kinase-α2 accentuates agonist-induced vascular smooth muscle contraction and high blood pressure in mice.

Wang S, Liang B, Viollet B, Zou MH.

Hypertension. 2011 May;57(5):1010-7. doi: 10.1161/HYPERTENSIONAHA.110.168906.

16.

Differential regulation of muscarinic M2 and M3 receptor signaling in gastrointestinal smooth muscle by caveolin-1.

Bhattacharya S, Mahavadi S, Al-Shboul O, Rajagopal S, Grider JR, Murthy KS.

Am J Physiol Cell Physiol. 2013 Aug 1;305(3):C334-47. doi: 10.1152/ajpcell.00334.2012.

17.

Mechanism regulating proasthmatic effects of prolonged homologous beta2-adrenergic receptor desensitization in airway smooth muscle.

Nino G, Hu A, Grunstein JS, Grunstein MM.

Am J Physiol Lung Cell Mol Physiol. 2009 Oct;297(4):L746-57. doi: 10.1152/ajplung.00079.2009.

18.

JunB mediates basal- and TGFβ1-induced smooth muscle cell contractility.

Ramachandran A, Gangopadhyay SS, Krishnan R, Ranpura SA, Rajendran K, Ram-Mohan S, Mulone M, Gong EM, Adam RM.

PLoS One. 2013;8(1):e53430. doi: 10.1371/journal.pone.0053430.

19.

Regulator of G-protein signaling-5 is a marker of hepatic stellate cells and expression mediates response to liver injury.

Bahrami AJ, Gunaje JJ, Hayes BJ, Riehle KJ, Kenerson HL, Yeung RS, Stempien-Otero AS, Campbell JS, Mahoney WM Jr.

PLoS One. 2014 Oct 7;9(10):e108505. doi: 10.1371/journal.pone.0108505.

20.

Carbachol-induced rabbit bladder smooth muscle contraction: roles of protein kinase C and Rho kinase.

Wang T, Kendig DM, Smolock EM, Moreland RS.

Am J Physiol Renal Physiol. 2009 Dec;297(6):F1534-42. doi: 10.1152/ajprenal.00095.2009.

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