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Items: 1 to 20 of 101

1.

Restoring leptin signaling reduces hyperlipidemia and improves vascular stiffness induced by chronic intermittent hypoxia.

Yang R, Sikka G, Larson J, Watts VL, Niu X, Ellis CL, Miller KL, Camara A, Reinke C, Savransky V, Polotsky VY, O'Donnell CP, Berkowitz DE, Barouch LA.

Am J Physiol Heart Circ Physiol. 2011 Apr;300(4):H1467-76. doi: 10.1152/ajpheart.00604.2009. Epub 2011 Jan 28.

2.

Intermittent hypoxia induces hyperlipidemia in lean mice.

Li J, Thorne LN, Punjabi NM, Sun CK, Schwartz AR, Smith PL, Marino RL, Rodriguez A, Hubbard WC, O'Donnell CP, Polotsky VY.

Circ Res. 2005 Sep 30;97(7):698-706. Epub 2005 Aug 25.

3.

Vascular and hepatic impact of short-term intermittent hypoxia in a mouse model of metabolic syndrome.

Trzepizur W, Gaceb A, Arnaud C, Ribuot C, Levy P, Martinez MC, Gagnadoux F, Andriantsitohaina R.

PLoS One. 2015 May 18;10(5):e0124637. doi: 10.1371/journal.pone.0124637. eCollection 2015.

4.

Interaction between age and obesity on cardiomyocyte contractile function: role of leptin and stress signaling.

Ren J, Dong F, Cai GJ, Zhao P, Nunn JM, Wold LE, Pei J.

PLoS One. 2010 Apr 9;5(4):e10085. doi: 10.1371/journal.pone.0010085. Erratum in: PLoS One. 2014;9(8): e105650. doi:10.1371/journal.pone.0105650.

5.

Dyslipidemia and atherosclerosis induced by chronic intermittent hypoxia are attenuated by deficiency of stearoyl coenzyme A desaturase.

Savransky V, Jun J, Li J, Nanayakkara A, Fonti S, Moser AB, Steele KE, Schweitzer MA, Patil SP, Bhanot S, Schwartz AR, Polotsky VY.

Circ Res. 2008 Nov 7;103(10):1173-80. doi: 10.1161/CIRCRESAHA.108.178533. Epub 2008 Oct 2.

6.

Chronic intermittent hypoxia upregulates genes of lipid biosynthesis in obese mice.

Li J, Grigoryev DN, Ye SQ, Thorne L, Schwartz AR, Smith PL, O'Donnell CP, Polotsky VY.

J Appl Physiol (1985). 2005 Nov;99(5):1643-8. Epub 2005 Jul 21.

7.

Leptin repletion restores depressed {beta}-adrenergic contractility in ob/ob mice independently of cardiac hypertrophy.

Minhas KM, Khan SA, Raju SV, Phan AC, Gonzalez DR, Skaf MW, Lee K, Tejani AD, Saliaris AP, Barouch LA, O'Donnell CP, Emala CW, Berkowitz DE, Hare JM.

J Physiol. 2005 Jun 1;565(Pt 2):463-74. Epub 2005 Mar 10. Erratum in: J Physiol. 2005 Aug 1;566(Pt 3):999. Saliaris, Anastasies P [corrected to Saliaris, Anastasios P].

8.

Obesity and intermittent hypoxia increase tumor growth in a mouse model of sleep apnea.

Almendros I, Montserrat JM, Torres M, Bonsignore MR, Chimenti L, Navajas D, Farré R.

Sleep Med. 2012 Dec;13(10):1254-60. doi: 10.1016/j.sleep.2012.08.012. Epub 2012 Nov 11.

PMID:
23149216
9.

Altered hepatic lipid metabolism contributes to nonalcoholic fatty liver disease in leptin-deficient Ob/Ob mice.

Perfield JW 2nd, Ortinau LC, Pickering RT, Ruebel ML, Meers GM, Rector RS.

J Obes. 2013;2013:296537. doi: 10.1155/2013/296537. Epub 2013 Jan 16.

10.

Down-regulation of hepatic stearoyl-CoA desaturase-1 expression by fucoxanthin via leptin signaling in diabetic/obese KK-A(y) mice.

Beppu F, Hosokawa M, Yim MJ, Shinoda T, Miyashita K.

Lipids. 2013 May;48(5):449-55. doi: 10.1007/s11745-013-3784-4. Epub 2013 Mar 21.

PMID:
23516000
11.

Altered metabolic responses to intermittent hypoxia in mice with partial deficiency of hypoxia-inducible factor-1alpha.

Li J, Bosch-Marce M, Nanayakkara A, Savransky V, Fried SK, Semenza GL, Polotsky VY.

Physiol Genomics. 2006 May 16;25(3):450-7. Epub 2006 Feb 28.

12.

Cardiac myocyte apoptosis is associated with increased DNA damage and decreased survival in murine models of obesity.

Barouch LA, Gao D, Chen L, Miller KL, Xu W, Phan AC, Kittleson MM, Minhas KM, Berkowitz DE, Wei C, Hare JM.

Circ Res. 2006 Jan 6;98(1):119-24. Epub 2005 Dec 8.

13.

Activation of the cardiac ciliary neurotrophic factor receptor reverses left ventricular hypertrophy in leptin-deficient and leptin-resistant obesity.

Raju SV, Zheng M, Schuleri KH, Phan AC, Bedja D, Saraiva RM, Yiginer O, Vandegaer K, Gabrielson KL, O'donnell CP, Berkowitz DE, Barouch LA, Hare JM.

Proc Natl Acad Sci U S A. 2006 Mar 14;103(11):4222-7. Epub 2006 Mar 6.

14.

Effect of deficiency in SREBP cleavage-activating protein on lipid metabolism during intermittent hypoxia.

Li J, Nanayakkara A, Jun J, Savransky V, Polotsky VY.

Physiol Genomics. 2007 Oct 22;31(2):273-80. Epub 2007 Jul 31.

15.

Role for stearoyl-CoA desaturase-1 in leptin-mediated weight loss.

Cohen P, Miyazaki M, Socci ND, Hagge-Greenberg A, Liedtke W, Soukas AA, Sharma R, Hudgins LC, Ntambi JM, Friedman JM.

Science. 2002 Jul 12;297(5579):240-3.

16.

Effects of angiotensin II on leptin and downstream leptin signaling in the carotid body during acute intermittent hypoxia.

Moreau JM, Messenger SA, Ciriello J.

Neuroscience. 2015 Dec 3;310:430-41. doi: 10.1016/j.neuroscience.2015.09.066. Epub 2015 Oct 9.

PMID:
26431621
17.

Leptin is essential in maintaining normal vascular compliance independent of body weight.

Sikka G, Yang R, Reid S, Benjo A, Koitabashi N, Camara A, Baraban E, O'Donnell CP, Berkowitz DE, Barouch LA.

Int J Obes (Lond). 2010 Jan;34(1):203-6. doi: 10.1038/ijo.2009.208. Epub 2009 Oct 6.

PMID:
19806156
18.

Loss of stearoyl-CoA desaturase 1 rescues cardiac function in obese leptin-deficient mice.

Dobrzyn P, Dobrzyn A, Miyazaki M, Ntambi JM.

J Lipid Res. 2010 Aug;51(8):2202-10. doi: 10.1194/jlr.M003780. Epub 2010 Apr 2.

19.

Hyperlipidemia and lipid peroxidation are dependent on the severity of chronic intermittent hypoxia.

Li J, Savransky V, Nanayakkara A, Smith PL, O'Donnell CP, Polotsky VY.

J Appl Physiol (1985). 2007 Feb;102(2):557-63. Epub 2006 Nov 2.

20.

Intermittent hypoxia in obese Zucker rats: cardiometabolic and inflammatory effects.

Briançon-Marjollet A, Monneret D, Henri M, Joyeux-Faure M, Totoson P, Cachot S, Faure P, Godin-Ribuot D.

Exp Physiol. 2016 Nov 1;101(11):1432-1442. doi: 10.1113/EP085783. Epub 2016 Oct 5.

PMID:
27615447

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