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Items: 1 to 20 of 107

1.

Interplay between HIV entry and transportin-SR2 dependency.

Thys W, De Houwer S, Demeulemeester J, Taltynov O, Vancraenenbroeck R, Gérard M, De Rijck J, Gijsbers R, Christ F, Debyser Z.

Retrovirology. 2011 Jan 30;8:7. doi: 10.1186/1742-4690-8-7.

2.

The requirement for cellular transportin 3 (TNPO3 or TRN-SR2) during infection maps to human immunodeficiency virus type 1 capsid and not integrase.

Krishnan L, Matreyek KA, Oztop I, Lee K, Tipper CH, Li X, Dar MJ, Kewalramani VN, Engelman A.

J Virol. 2010 Jan;84(1):397-406. doi: 10.1128/JVI.01899-09.

3.

The HIV-1 integrase mutant R263A/K264A is 2-fold defective for TRN-SR2 binding and viral nuclear import.

De Houwer S, Demeulemeester J, Thys W, Rocha S, Dirix L, Gijsbers R, Christ F, Debyser Z.

J Biol Chem. 2014 Sep 5;289(36):25351-61. doi: 10.1074/jbc.M113.533281.

4.

Transportin-SR2 imports HIV into the nucleus.

Christ F, Thys W, De Rijck J, Gijsbers R, Albanese A, Arosio D, Emiliani S, Rain JC, Benarous R, Cereseto A, Debyser Z.

Curr Biol. 2008 Aug 26;18(16):1192-202. doi: 10.1016/j.cub.2008.07.079.

5.

Interaction of transportin-SR2 with Ras-related nuclear protein (Ran) GTPase.

Taltynov O, Demeulemeester J, Christ F, De Houwer S, Tsirkone VG, Gerard M, Weeks SD, Strelkov SV, Debyser Z.

J Biol Chem. 2013 Aug 30;288(35):25603-13. doi: 10.1074/jbc.M113.484345.

6.

Identification of residues in the C-terminal domain of HIV-1 integrase that mediate binding to the transportin-SR2 protein.

De Houwer S, Demeulemeester J, Thys W, Taltynov O, Zmajkovicova K, Christ F, Debyser Z.

J Biol Chem. 2012 Oct 5;287(41):34059-68. doi: 10.1074/jbc.M112.387944.

7.
8.

The host proteins transportin SR2/TNPO3 and cyclophilin A exert opposing effects on HIV-1 uncoating.

Shah VB, Shi J, Hout DR, Oztop I, Krishnan L, Ahn J, Shotwell MS, Engelman A, Aiken C.

J Virol. 2013 Jan;87(1):422-32. doi: 10.1128/JVI.07177-11.

9.

Transportin 3 and importin α are required for effective nuclear import of HIV-1 integrase in virus-infected cells.

Levin A, Hayouka Z, Friedler A, Loyter A.

Nucleus. 2010 Sep-Oct;1(5):422-31. doi: 10.4161/nucl.1.5.12903.

10.

HIV-1 infection: going nuclear with TNPO3/Transportin-SR2 and integrase.

Luban J.

Curr Biol. 2008 Aug 26;18(16):R710-3. doi: 10.1016/j.cub.2008.07.037.

11.

Interaction of the HIV-1 intasome with transportin 3 protein (TNPO3 or TRN-SR2).

Larue R, Gupta K, Wuensch C, Shkriabai N, Kessl JJ, Danhart E, Feng L, Taltynov O, Christ F, Van Duyne GD, Debyser Z, Foster MP, Kvaratskhelia M.

J Biol Chem. 2012 Oct 5;287(41):34044-58. doi: 10.1074/jbc.M112.384669.

12.

Transportin-SR2 mediates nuclear import of phosphorylated SR proteins.

Lai MC, Lin RI, Tarn WY.

Proc Natl Acad Sci U S A. 2001 Aug 28;98(18):10154-9.

13.
15.

Transportin 3 promotes a nuclear maturation step required for efficient HIV-1 integration.

Zhou L, Sokolskaja E, Jolly C, James W, Cowley SA, Fassati A.

PLoS Pathog. 2011 Aug;7(8):e1002194. doi: 10.1371/journal.ppat.1002194.

16.

HIV-1 capsid-cyclophilin interactions determine nuclear import pathway, integration targeting and replication efficiency.

Schaller T, Ocwieja KE, Rasaiyaah J, Price AJ, Brady TL, Roth SL, Hué S, Fletcher AJ, Lee K, KewalRamani VN, Noursadeghi M, Jenner RG, James LC, Bushman FD, Towers GJ.

PLoS Pathog. 2011 Dec;7(12):e1002439. doi: 10.1371/journal.ppat.1002439.

18.

The cargo-binding domain of transportin 3 is required for lentivirus nuclear import.

Logue EC, Taylor KT, Goff PH, Landau NR.

J Virol. 2011 Dec;85(24):12950-61. doi: 10.1128/JVI.05384-11.

19.

Differential effects of human immunodeficiency virus type 1 capsid and cellular factors nucleoporin 153 and LEDGF/p75 on the efficiency and specificity of viral DNA integration.

Koh Y, Wu X, Ferris AL, Matreyek KA, Smith SJ, Lee K, KewalRamani VN, Hughes SH, Engelman A.

J Virol. 2013 Jan;87(1):648-58. doi: 10.1128/JVI.01148-12.

20.

Lv2, a novel postentry restriction, is mediated by both capsid and envelope.

Schmitz C, Marchant D, Neil SJ, Aubin K, Reuter S, Dittmar MT, McKnight A.

J Virol. 2004 Feb;78(4):2006-16.

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