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Items: 1 to 20 of 100

1.

Enhanced inhibition of lung adenocarcinoma by combinatorial treatment with indole-3-carbinol and silibinin in A/J mice.

Dagne A, Melkamu T, Schutten MM, Qian X, Upadhyaya P, Luo X, Kassie F.

Carcinogenesis. 2011 Apr;32(4):561-7. doi: 10.1093/carcin/bgr010. Epub 2011 Jan 27.

2.

Inhibition of lung carcinogenesis and critical cancer-related signaling pathways by N-acetyl-S-(N-2-phenethylthiocarbamoyl)-l-cysteine, indole-3-carbinol and myo-inositol, alone and in combination.

Kassie F, Melkamu T, Endalew A, Upadhyaya P, Luo X, Hecht SS.

Carcinogenesis. 2010 Sep;31(9):1634-41. doi: 10.1093/carcin/bgq139. Epub 2010 Jul 5.

3.

Combinations of indole-3-carbinol and silibinin suppress inflammation-driven mouse lung tumorigenesis by modulating critical cell cycle regulators.

Song JM, Qian X, Molla K, Teferi F, Upadhyaya P, O Sullivan G, Luo X, Kassie F.

Carcinogenesis. 2015 Jun;36(6):666-75. doi: 10.1093/carcin/bgv054. Epub 2015 Apr 20.

4.

Dose-dependent inhibition of tobacco smoke carcinogen-induced lung tumorigenesis in A/J mice by indole-3-carbinol.

Kassie F, Matise I, Negia M, Upadhyaya P, Hecht SS.

Cancer Prev Res (Phila). 2008 Dec;1(7):568-76. doi: 10.1158/1940-6207.CAPR-08-0064.

6.

Indole-3-carbinol inhibited tobacco smoke carcinogen-induced lung adenocarcinoma in A/J mice when administered during the post-initiation or progression phase of lung tumorigenesis.

Qian X, Melkamu T, Upadhyaya P, Kassie F.

Cancer Lett. 2011 Dec 1;311(1):57-65. doi: 10.1016/j.canlet.2011.06.023. Epub 2011 Jul 2.

7.

Inhibition of vinyl carbamate-induced pulmonary adenocarcinoma by indole-3-carbinol and myo-inositol in A/J mice.

Kassie F, Kalscheuer S, Matise I, Ma L, Melkamu T, Upadhyaya P, Hecht SS.

Carcinogenesis. 2010 Feb;31(2):239-45. doi: 10.1093/carcin/bgp174. Epub 2009 Jul 22.

10.

Combinations of N-Acetyl-S-(N-2-Phenethylthiocarbamoyl)-L-Cysteine and myo-inositol inhibit tobacco carcinogen-induced lung adenocarcinoma in mice.

Kassie F, Matise I, Negia M, Lahti D, Pan Y, Scherber R, Upadhyaya P, Hecht SS.

Cancer Prev Res (Phila). 2008 Sep;1(4):285-97. doi: 10.1158/1940-6207.CAPR-08-0012.

11.

RNA-sequencing studies identify genes differentially regulated during inflammation-driven lung tumorigenesis and targeted by chemopreventive agents.

Qian X, Khammanivong A, Song JM, Teferi F, Upadhyaya P, Dickerson E, Kassie F.

Inflamm Res. 2015 May;64(5):343-61. doi: 10.1007/s00011-015-0815-z. Epub 2015 Mar 21.

12.

Indole-3-carbinol inhibits cell proliferation and induces apoptosis in Hep-2 laryngeal cancer cells.

Wang YQ, Chen C, Chen Z, Xu Y, Wang Y, Xiao BK, Chen SM, Tao ZZ.

Oncol Rep. 2013 Jul;30(1):227-33. doi: 10.3892/or.2013.2411. Epub 2013 Apr 22.

PMID:
23604413
15.

Indole-3-carbinol induces apoptosis through p53 and activation of caspase-8 pathway in lung cancer A549 cells.

Choi HS, Cho MC, Lee HG, Yoon DY.

Food Chem Toxicol. 2010 Mar;48(3):883-90. doi: 10.1016/j.fct.2009.12.028. Epub 2010 Jan 6.

PMID:
20060030
16.

Intranasal delivery of liposomal indole-3-carbinol improves its pulmonary bioavailability.

Song JM, Kirtane AR, Upadhyaya P, Qian X, Balbo S, Teferi F, Panyam J, Kassie F.

Int J Pharm. 2014 Dec 30;477(1-2):96-101. doi: 10.1016/j.ijpharm.2014.10.018. Epub 2014 Oct 11.

17.

Silibinin suppresses in vivo growth of human prostate carcinoma PC-3 tumor xenograft.

Singh RP, Deep G, Blouin MJ, Pollak MN, Agarwal R.

Carcinogenesis. 2007 Dec;28(12):2567-74. Epub 2007 Oct 4.

PMID:
17916909
18.

Silibinin prevents lung tumorigenesis in wild-type but not in iNOS-/- mice: potential of real-time micro-CT in lung cancer chemoprevention studies.

Ramasamy K, Dwyer-Nield LD, Serkova NJ, Hasebroock KM, Tyagi A, Raina K, Singh RP, Malkinson AM, Agarwal R.

Clin Cancer Res. 2011 Feb 15;17(4):753-61. doi: 10.1158/1078-0432.CCR-10-2290. Epub 2010 Dec 10.

19.

Phenethyl isothiocyanate and sulforaphane and their N-acetylcysteine conjugates inhibit malignant progression of lung adenomas induced by tobacco carcinogens in A/J mice.

Conaway CC, Wang CX, Pittman B, Yang YM, Schwartz JE, Tian D, McIntee EJ, Hecht SS, Chung FL.

Cancer Res. 2005 Sep 15;65(18):8548-57.

20.

Silibinin protects against photocarcinogenesis via modulation of cell cycle regulators, mitogen-activated protein kinases, and Akt signaling.

Mallikarjuna G, Dhanalakshmi S, Singh RP, Agarwal C, Agarwal R.

Cancer Res. 2004 Sep 1;64(17):6349-56.

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