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Items: 1 to 20 of 101

1.

A sensitive mass spectrometry method for simultaneous quantification of DNA methylation and hydroxymethylation levels in biological samples.

Le T, Kim KP, Fan G, Faull KF.

Anal Biochem. 2011 May 15;412(2):203-9. doi: 10.1016/j.ab.2011.01.026. Epub 2011 Jan 24.

2.

Lineage-specific distribution of high levels of genomic 5-hydroxymethylcytosine in mammalian development.

Ruzov A, Tsenkina Y, Serio A, Dudnakova T, Fletcher J, Bai Y, Chebotareva T, Pells S, Hannoun Z, Sullivan G, Chandran S, Hay DC, Bradley M, Wilmut I, De Sousa P.

Cell Res. 2011 Sep;21(9):1332-42. doi: 10.1038/cr.2011.113. Epub 2011 Jul 12.

3.
4.

Dynamic readers for 5-(hydroxy)methylcytosine and its oxidized derivatives.

Spruijt CG, Gnerlich F, Smits AH, Pfaffeneder T, Jansen PW, Bauer C, Münzel M, Wagner M, Müller M, Khan F, Eberl HC, Mensinga A, Brinkman AB, Lephikov K, Müller U, Walter J, Boelens R, van Ingen H, Leonhardt H, Carell T, Vermeulen M.

Cell. 2013 Feb 28;152(5):1146-59. doi: 10.1016/j.cell.2013.02.004. Epub 2013 Feb 21.

5.

High sensitivity 5-hydroxymethylcytosine detection in Balb/C brain tissue.

Davis T, Vaisvila R.

J Vis Exp. 2011 Feb 1;(48). pii: 2661. doi: 10.3791/2661.

6.

Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1.

Tahiliani M, Koh KP, Shen Y, Pastor WA, Bandukwala H, Brudno Y, Agarwal S, Iyer LM, Liu DR, Aravind L, Rao A.

Science. 2009 May 15;324(5929):930-5. doi: 10.1126/science.1170116. Epub 2009 Apr 16.

7.

Quantification of 5-methylcytosine and 5-hydroxymethylcytosine in genomic DNA from hepatocellular carcinoma tissues by capillary hydrophilic-interaction liquid chromatography/quadrupole TOF mass spectrometry.

Chen ML, Shen F, Huang W, Qi JH, Wang Y, Feng YQ, Liu SM, Yuan BF.

Clin Chem. 2013 May;59(5):824-32. doi: 10.1373/clinchem.2012.193938. Epub 2013 Jan 23.

8.

Integrated detection of both 5-mC and 5-hmC by high-throughput tag sequencing technology highlights methylation reprogramming of bivalent genes during cellular differentiation.

Gao F, Xia Y, Wang J, Luo H, Gao Z, Han X, Zhang J, Huang X, Yao Y, Lu H, Yi N, Zhou B, Lin Z, Wen B, Zhang X, Yang H, Wang J.

Epigenetics. 2013 Apr;8(4):421-30. doi: 10.4161/epi.24280. Epub 2013 Mar 15.

9.

Quantification of Oxidized 5-Methylcytosine Bases and TET Enzyme Activity.

Liu MY, DeNizio JE, Kohli RM.

Methods Enzymol. 2016;573:365-85. doi: 10.1016/bs.mie.2015.12.006. Epub 2016 Feb 1.

10.

Array-based assay detects genome-wide 5-mC and 5-hmC in the brains of humans, non-human primates, and mice.

Chopra P, Papale LA, White AT, Hatch A, Brown RM, Garthwaite MA, Roseboom PH, Golos TG, Warren ST, Alisch RS.

BMC Genomics. 2014 Feb 13;15:131. doi: 10.1186/1471-2164-15-131.

11.

Replacement of Oct4 by Tet1 during iPSC induction reveals an important role of DNA methylation and hydroxymethylation in reprogramming.

Gao Y, Chen J, Li K, Wu T, Huang B, Liu W, Kou X, Zhang Y, Huang H, Jiang Y, Yao C, Liu X, Lu Z, Xu Z, Kang L, Chen J, Wang H, Cai T, Gao S.

Cell Stem Cell. 2013 Apr 4;12(4):453-69. doi: 10.1016/j.stem.2013.02.005. Epub 2013 Mar 14.

12.

MLML: consistent simultaneous estimates of DNA methylation and hydroxymethylation.

Qu J, Zhou M, Song Q, Hong EE, Smith AD.

Bioinformatics. 2013 Oct 15;29(20):2645-6. doi: 10.1093/bioinformatics/btt459. Epub 2013 Aug 21.

13.

Robust quantitative assessments of cytosine modifications and changes in the expressions of related enzymes in gastric cancer.

Du C, Kurabe N, Matsushima Y, Suzuki M, Kahyo T, Ohnishi I, Tanioka F, Tajima S, Goto M, Yamada H, Tao H, Shinmura K, Konno H, Sugimura H.

Gastric Cancer. 2015 Jul;18(3):516-25. doi: 10.1007/s10120-014-0409-4. Epub 2014 Aug 7.

PMID:
25098926
14.

Subtelomeric hotspots of aberrant 5-hydroxymethylcytosine-mediated epigenetic modifications during reprogramming to pluripotency.

Wang T, Wu H, Li Y, Szulwach KE, Lin L, Li X, Chen IP, Goldlust IS, Chamberlain SJ, Dodd A, Gong H, Ananiev G, Han JW, Yoon YS, Rudd MK, Yu M, Song CX, He C, Chang Q, Warren ST, Jin P.

Nat Cell Biol. 2013 Jun;15(6):700-11. doi: 10.1038/ncb2748. Epub 2013 May 19.

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16.

Genome-wide hydroxymethylation tested using the HELP-GT assay shows redistribution in cancer.

Bhattacharyya S, Yu Y, Suzuki M, Campbell N, Mazdo J, Vasanthakumar A, Bhagat TD, Nischal S, Christopeit M, Parekh S, Steidl U, Godley L, Maitra A, Greally JM, Verma A.

Nucleic Acids Res. 2013 Sep;41(16):e157. doi: 10.1093/nar/gkt601. Epub 2013 Jul 16.

17.

Dynamic changes in DNA methylation and hydroxymethylation when hES cells undergo differentiation toward a neuronal lineage.

Kim M, Park YK, Kang TW, Lee SH, Rhee YH, Park JL, Kim HJ, Lee D, Lee D, Kim SY, Kim YS.

Hum Mol Genet. 2014 Feb 1;23(3):657-67. doi: 10.1093/hmg/ddt453. Epub 2013 Sep 18.

PMID:
24087792
18.
19.

Ascorbate induces ten-eleven translocation (Tet) methylcytosine dioxygenase-mediated generation of 5-hydroxymethylcytosine.

Minor EA, Court BL, Young JI, Wang G.

J Biol Chem. 2013 May 10;288(19):13669-74. doi: 10.1074/jbc.C113.464800. Epub 2013 Apr 2.

20.

Simultaneous determination of global DNA methylation and hydroxymethylation levels by hydrophilic interaction liquid chromatography-tandem mass spectrometry.

Zhang L, Zhang L, Zhou K, Ye X, Zhang J, Xie A, Chen L, Kang JX, Cai C.

J Biomol Screen. 2012 Aug;17(7):877-84. doi: 10.1177/1087057112447946. Epub 2012 May 29.

PMID:
22644266

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