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Different nuclease requirements for exosome-mediated degradation of normal and nonstop mRNAs.

Schaeffer D, van Hoof A.

Proc Natl Acad Sci U S A. 2011 Feb 8;108(6):2366-71. doi: 10.1073/pnas.1013180108. Epub 2011 Jan 24.


Exosome-mediated recognition and degradation of mRNAs lacking a termination codon.

van Hoof A, Frischmeyer PA, Dietz HC, Parker R.

Science. 2002 Mar 22;295(5563):2262-4.


The exosome contains domains with specific endoribonuclease, exoribonuclease and cytoplasmic mRNA decay activities.

Schaeffer D, Tsanova B, Barbas A, Reis FP, Dastidar EG, Sanchez-Rotunno M, Arraiano CM, van Hoof A.

Nat Struct Mol Biol. 2009 Jan;16(1):56-62. doi: 10.1038/nsmb.1528. Epub 2008 Dec 7.


A genomic screen in yeast reveals novel aspects of nonstop mRNA metabolism.

Wilson MA, Meaux S, van Hoof A.

Genetics. 2007 Oct;177(2):773-84. Epub 2007 Jul 29.


Dom34:hbs1 plays a general role in quality-control systems by dissociation of a stalled ribosome at the 3' end of aberrant mRNA.

Tsuboi T, Kuroha K, Kudo K, Makino S, Inoue E, Kashima I, Inada T.

Mol Cell. 2012 May 25;46(4):518-29. doi: 10.1016/j.molcel.2012.03.013. Epub 2012 Apr 11.


Degradation of mRNAs that lack a stop codon: a decade of nonstop progress.

Klauer AA, van Hoof A.

Wiley Interdiscip Rev RNA. 2012 Sep-Oct;3(5):649-60. doi: 10.1002/wrna.1124. Epub 2012 Jun 27. Review.


Conserved functions of human Pelota in mRNA quality control of nonstop mRNA.

Ikeuchi K, Yazaki E, Kudo K, Inada T.

FEBS Lett. 2016 Sep;590(18):3254-63. doi: 10.1002/1873-3468.12366. Epub 2016 Sep 7.


Ski7p G protein interacts with the exosome and the Ski complex for 3'-to-5' mRNA decay in yeast.

Araki Y, Takahashi S, Kobayashi T, Kajiho H, Hoshino S, Katada T.

EMBO J. 2001 Sep 3;20(17):4684-93.


Molecular biology. Skiing toward nonstop mRNA decay.

Maquat LE.

Science. 2002 Mar 22;295(5563):2221-2. No abstract available. Erratum in: Science 2002 Jul 19;297(5580):337.


Initiation-mediated mRNA decay in yeast affects heat-shock mRNAs, and works through decapping and 5'-to-3' hydrolysis.

Heikkinen HL, Llewellyn SA, Barnes CA.

Nucleic Acids Res. 2003 Jul 15;31(14):4006-16.


Comparison of the yeast and human nuclear exosome complexes.

Sloan KE, Schneider C, Watkins NJ.

Biochem Soc Trans. 2012 Aug;40(4):850-5. doi: 10.1042/BST20120061. Review.


The fission yeast MTREC complex targets CUTs and unspliced pre-mRNAs to the nuclear exosome.

Zhou Y, Zhu J, Schermann G, Ohle C, Bendrin K, Sugioka-Sugiyama R, Sugiyama T, Fischer T.

Nat Commun. 2015 May 20;6:7050. doi: 10.1038/ncomms8050.


The human core exosome interacts with differentially localized processive RNases: hDIS3 and hDIS3L.

Tomecki R, Kristiansen MS, Lykke-Andersen S, Chlebowski A, Larsen KM, Szczesny RJ, Drazkowska K, Pastula A, Andersen JS, Stepien PP, Dziembowski A, Jensen TH.

EMBO J. 2010 Jul 21;29(14):2342-57. doi: 10.1038/emboj.2010.121. Epub 2010 Jun 8.


Exosome Cofactors Connect Transcription Termination to RNA Processing by Guiding Terminated Transcripts to the Appropriate Exonuclease within the Nuclear Exosome.

Kim K, Heo DH, Kim I, Suh JY, Kim M.

J Biol Chem. 2016 Jun 17;291(25):13229-42. doi: 10.1074/jbc.M116.715771. Epub 2016 Apr 13.

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