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Items: 1 to 20 of 130

1.

Reduction of disulphide bonds unmasks potent antimicrobial activity of human β-defensin 1.

Schroeder BO, Wu Z, Nuding S, Groscurth S, Marcinowski M, Beisner J, Buchner J, Schaller M, Stange EF, Wehkamp J.

Nature. 2011 Jan 20;469(7330):419-23. doi: 10.1038/nature09674.

PMID:
21248850
2.

Immunology: Peptide gets in shape for self-defence.

Lehrer RI.

Nature. 2011 Jan 20;469(7330):309-10. doi: 10.1038/469309a. No abstract available.

PMID:
21248835
3.

Cell-mediated reduction of human β-defensin 1: a major role for mucosal thioredoxin.

Jaeger SU, Schroeder BO, Meyer-Hoffert U, Courth L, Fehr SN, Gersemann M, Stange EF, Wehkamp J.

Mucosal Immunol. 2013 Nov;6(6):1179-90. doi: 10.1038/mi.2013.17. Epub 2013 Apr 10.

4.

Bactericidal activity of mouse α-defensin cryptdin-4 predominantly affects noncommensal bacteria.

Masuda K, Sakai N, Nakamura K, Yoshioka S, Ayabe T.

J Innate Immun. 2011;3(3):315-26. doi: 10.1159/000322037. Epub 2010 Nov 22.

5.

Paneth cells, defensins, and the commensal microbiota: a hypothesis on intimate interplay at the intestinal mucosa.

Salzman NH, Underwood MA, Bevins CL.

Semin Immunol. 2007 Apr;19(2):70-83. Epub 2007 May 7. Review.

PMID:
17485224
6.

Expression and regulation of the human beta-defensins hBD-1 and hBD-2 in intestinal epithelium.

O'Neil DA, Porter EM, Elewaut D, Anderson GM, Eckmann L, Ganz T, Kagnoff MF.

J Immunol. 1999 Dec 15;163(12):6718-24.

7.

[Human beta-defensin 1: from defence to offence].

Schroeder BO, Stange EF, Wehkamp J.

Z Gastroenterol. 2012 Nov;50(11):1171-5. doi: 10.1055/s-0032-1312865. Epub 2012 Nov 13. Review. German.

PMID:
23150110
8.

Antimicrobial activity of human β-defensins against lactic acid bacteria.

Wang XF, Tian F, Cao RM, Li J, Wu SM, Guo XK, Chen TX.

Nat Prod Res. 2015;29(22):2164-6. doi: 10.1080/14786419.2014.996754. Epub 2015 Jan 6.

PMID:
25560646
9.

Human beta-defensin 2 but not beta-defensin 1 is expressed preferentially in colonic mucosa of inflammatory bowel disease.

Wehkamp J, Fellermann K, Herrlinger KR, Baxmann S, Schmidt K, Schwind B, Duchrow M, Wohlschläger C, Feller AC, Stange EF.

Eur J Gastroenterol Hepatol. 2002 Jul;14(7):745-52.

PMID:
12169983
10.

Digested and fermented green kiwifruit increases human β-defensin 1 and 2 production in vitro.

Bentley-Hewitt KL, Blatchford PA, Parkar SG, Ansell J, Pernthaner A.

Plant Foods Hum Nutr. 2012 Sep;67(3):208-14.

PMID:
22872469
11.

Structural and functional characterization of hBD-1(Ser35), a peptide deduced from a DEFB1 polymorphism.

Circo R, Skerlavaj B, Gennaro R, Amoroso A, Zanetti M.

Biochem Biophys Res Commun. 2002 Apr 26;293(1):586-92.

PMID:
12054642
12.

Identification of a novel, multifunctional beta-defensin (human beta-defensin 3) with specific antimicrobial activity. Its interaction with plasma membranes of Xenopus oocytes and the induction of macrophage chemoattraction.

García JR, Jaumann F, Schulz S, Krause A, Rodríguez-Jiménez J, Forssmann U, Adermann K, Klüver E, Vogelmeier C, Becker D, Hedrich R, Forssmann WG, Bals R.

Cell Tissue Res. 2001 Nov;306(2):257-64.

PMID:
11702237
13.

Antimicrobial activity of innate immune molecules against Streptococcus pneumoniae, Moraxella catarrhalis and nontypeable Haemophilus influenzae.

Lee HY, Andalibi A, Webster P, Moon SK, Teufert K, Kang SH, Li JD, Nagura M, Ganz T, Lim DJ.

BMC Infect Dis. 2004 May 5;4:12.

14.

Human β-defensin 4 with non-native disulfide bridges exhibit antimicrobial activity.

Sharma H, Nagaraj R.

PLoS One. 2015 Mar 18;10(3):e0119525. doi: 10.1371/journal.pone.0119525. eCollection 2015.

15.

Paneth cell α-defensin 6 (HD-6) is an antimicrobial peptide.

Schroeder BO, Ehmann D, Precht JC, Castillo PA, Küchler R, Berger J, Schaller M, Stange EF, Wehkamp J.

Mucosal Immunol. 2015 May;8(3):661-71. doi: 10.1038/mi.2014.100. Epub 2014 Nov 5.

16.

Molecular cloning and characterization of three beta-defensins from canine testes.

Sang Y, Ortega MT, Blecha F, Prakash O, Melgarejo T.

Infect Immun. 2005 May;73(5):2611-20.

17.

Antimicrobial activities of human beta-defensins against Bacillus species.

Yadava P, Zhang C, Sun J, Hughes JA.

Int J Antimicrob Agents. 2006 Aug;28(2):132-7. Epub 2006 Jun 21.

PMID:
16797165
18.

Production of beta-defensin antimicrobial peptides by the oral mucosa and salivary glands.

Mathews M, Jia HP, Guthmiller JM, Losh G, Graham S, Johnson GK, Tack BF, McCray PB Jr.

Infect Immun. 1999 Jun;67(6):2740-5.

19.

Structure-activity relationships in defensin dimers: a novel link between beta-defensin tertiary structure and antimicrobial activity.

Campopiano DJ, Clarke DJ, Polfer NC, Barran PE, Langley RJ, Govan JR, Maxwell A, Dorin JR.

J Biol Chem. 2004 Nov 19;279(47):48671-9. Epub 2004 Aug 17.

20.

Isolation and characterization of human beta -defensin-3, a novel human inducible peptide antibiotic.

Harder J, Bartels J, Christophers E, Schroder JM.

J Biol Chem. 2001 Feb 23;276(8):5707-13. Epub 2000 Nov 20.

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