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Items: 1 to 20 of 274

1.

HMGB1 acts on microglia Mac1 to mediate chronic neuroinflammation that drives progressive neurodegeneration.

Gao HM, Zhou H, Zhang F, Wilson BC, Kam W, Hong JS.

J Neurosci. 2011 Jan 19;31(3):1081-92. doi: 10.1523/JNEUROSCI.3732-10.2011.

2.

Macrophage antigen complex-1 mediates reactive microgliosis and progressive dopaminergic neurodegeneration in the MPTP model of Parkinson's disease.

Hu X, Zhang D, Pang H, Caudle WM, Li Y, Gao H, Liu Y, Qian L, Wilson B, Di Monte DA, Ali SF, Zhang J, Block ML, Hong JS.

J Immunol. 2008 Nov 15;181(10):7194-204.

3.

Microglial MAC1 receptor and PI3K are essential in mediating β-amyloid peptide-induced microglial activation and subsequent neurotoxicity.

Zhang D, Hu X, Qian L, Chen SH, Zhou H, Wilson B, Miller DS, Hong JS.

J Neuroinflammation. 2011 Jan 13;8(1):3. doi: 10.1186/1742-2094-8-3.

4.

Resveratrol protects dopamine neurons against lipopolysaccharide-induced neurotoxicity through its anti-inflammatory actions.

Zhang F, Shi JS, Zhou H, Wilson B, Hong JS, Gao HM.

Mol Pharmacol. 2010 Sep;78(3):466-77. doi: 10.1124/mol.110.064535. Epub 2010 Jun 16. Erratum in: Mol Pharmacol. 2010 Nov;78(5):981.

5.
6.

Squamosamide derivative FLZ protects dopaminergic neurons against inflammation-mediated neurodegeneration through the inhibition of NADPH oxidase activity.

Zhang D, Hu X, Wei SJ, Liu J, Gao H, Qian L, Wilson B, Liu G, Hong JS.

J Neuroinflammation. 2008 May 28;5:21. doi: 10.1186/1742-2094-5-21.

7.

NADPH oxidase mediates lipopolysaccharide-induced neurotoxicity and proinflammatory gene expression in activated microglia.

Qin L, Liu Y, Wang T, Wei SJ, Block ML, Wilson B, Liu B, Hong JS.

J Biol Chem. 2004 Jan 9;279(2):1415-21. Epub 2003 Oct 24.

8.
10.

MAC1 mediates LPS-induced production of superoxide by microglia: the role of pattern recognition receptors in dopaminergic neurotoxicity.

Pei Z, Pang H, Qian L, Yang S, Wang T, Zhang W, Wu X, Dallas S, Wilson B, Reece JM, Miller DS, Hong JS, Block ML.

Glia. 2007 Oct;55(13):1362-73.

PMID:
17654704
11.

Distinct role for microglia in rotenone-induced degeneration of dopaminergic neurons.

Gao HM, Hong JS, Zhang W, Liu B.

J Neurosci. 2002 Feb 1;22(3):782-90.

12.

Clozapine protects dopaminergic neurons from inflammation-induced damage by inhibiting microglial overactivation.

Hu X, Zhou H, Zhang D, Yang S, Qian L, Wu HM, Chen PS, Wilson B, Gao HM, Lu RB, Hong JS.

J Neuroimmune Pharmacol. 2012 Mar;7(1):187-201. doi: 10.1007/s11481-011-9309-0. Epub 2011 Aug 26.

13.
14.

Formyl-methionyl-leucyl-phenylalanine-induced dopaminergic neurotoxicity via microglial activation: a mediator between peripheral infection and neurodegeneration?

Gao X, Hu X, Qian L, Yang S, Zhang W, Zhang D, Wu X, Fraser A, Wilson B, Flood PM, Block M, Hong JS.

Environ Health Perspect. 2008 May;116(5):593-8. doi: 10.1289/ehp.11031.

15.

beta2 Adrenergic receptor activation induces microglial NADPH oxidase activation and dopaminergic neurotoxicity through an ERK-dependent/protein kinase A-independent pathway.

Qian L, Hu X, Zhang D, Snyder A, Wu HM, Li Y, Wilson B, Lu RB, Hong JS, Flood PM.

Glia. 2009 Nov 15;57(15):1600-9. doi: 10.1002/glia.20873.

16.

Neuroinflammation and α-synuclein dysfunction potentiate each other, driving chronic progression of neurodegeneration in a mouse model of Parkinson's disease.

Gao HM, Zhang F, Zhou H, Kam W, Wilson B, Hong JS.

Environ Health Perspect. 2011 Jun;119(6):807-14. doi: 10.1289/ehp.1003013. Epub 2011 Jan 18.

17.

Verapamil protects dopaminergic neuron damage through a novel anti-inflammatory mechanism by inhibition of microglial activation.

Liu Y, Lo YC, Qian L, Crews FT, Wilson B, Chen HL, Wu HM, Chen SH, Wei K, Lu RB, Ali S, Hong JS.

Neuropharmacology. 2011 Feb-Mar;60(2-3):373-80. doi: 10.1016/j.neuropharm.2010.10.002. Epub 2010 Oct 13.

18.

Regional difference in susceptibility to lipopolysaccharide-induced neurotoxicity in the rat brain: role of microglia.

Kim WG, Mohney RP, Wilson B, Jeohn GH, Liu B, Hong JS.

J Neurosci. 2000 Aug 15;20(16):6309-16.

19.

Substance P exacerbates dopaminergic neurodegeneration through neurokinin-1 receptor-independent activation of microglial NADPH oxidase.

Wang Q, Chu CH, Qian L, Chen SH, Wilson B, Oyarzabal E, Jiang L, Ali S, Robinson B, Kim HC, Hong JS.

J Neurosci. 2014 Sep 10;34(37):12490-503. doi: 10.1523/JNEUROSCI.2238-14.2014.

20.

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