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Items: 1 to 20 of 85

1.

BCL-2 is a downstream target of ATF5 that mediates the prosurvival function of ATF5 in a cell type-dependent manner.

Dluzen D, Li G, Tacelosky D, Moreau M, Liu DX.

J Biol Chem. 2011 Mar 4;286(9):7705-13. doi: 10.1074/jbc.M110.207639. Epub 2011 Jan 6.

2.

HSP70 protein promotes survival of C6 and U87 glioma cells by inhibition of ATF5 degradation.

Li G, Xu Y, Guan D, Liu Z, Liu DX.

J Biol Chem. 2011 Jun 10;286(23):20251-9. doi: 10.1074/jbc.M110.211771. Epub 2011 Apr 25.

3.

Interference with ATF5 function enhances the sensitivity of human pancreatic cancer cells to paclitaxel-induced apoptosis.

Hu M, Wang B, Qian D, Li L, Zhang L, Song X, Liu DX.

Anticancer Res. 2012 Oct;32(10):4385-94.

PMID:
23060563
4.

ATF5 is overexpressed in epithelial ovarian carcinomas and interference with its function increases apoptosis through the downregulation of Bcl-2 in SKOV-3 cells.

Chen A, Qian D, Wang B, Hu M, Lu J, Qi Y, Liu DX.

Int J Gynecol Pathol. 2012 Nov;31(6):532-7. doi: 10.1097/PGP.0b013e31824df26b.

PMID:
23018213
5.

Identification of a novel DNA binding site and a transcriptional target for activating transcription factor 5 in c6 glioma and mcf-7 breast cancer cells.

Li G, Li W, Angelastro JM, Greene LA, Liu DX.

Mol Cancer Res. 2009 Jun;7(6):933-43. doi: 10.1158/1541-7786.MCR-08-0365. Epub 2009 Jun 16.

6.

Selective destruction of glioblastoma cells by interference with the activity or expression of ATF5.

Angelastro JM, Canoll PD, Kuo J, Weicker M, Costa A, Bruce JN, Greene LA.

Oncogene. 2006 Feb 9;25(6):907-16.

PMID:
16170340
7.

Re-expression of transcription factor ATF5 in hepatocellular carcinoma induces G2-M arrest.

Gho JW, Ip WK, Chan KY, Law PT, Lai PB, Wong N.

Cancer Res. 2008 Aug 15;68(16):6743-51. doi: 10.1158/0008-5472.CAN-07-6469.

8.

Influence of Bax or Bcl-2 overexpression on the ceramide-dependent apoptotic pathway in glioma cells.

Sawada M, Nakashima S, Banno Y, Yamakawa H, Takenaka K, Shinoda J, Nishimura Y, Sakai N, Nozawa Y.

Oncogene. 2000 Jul 20;19(31):3508-20. Erratum in: Oncogene. 2006 Nov 30;25(56):7440.

9.

A genome-wide RNA interference screen reveals an essential CREB3L2-ATF5-MCL1 survival pathway in malignant glioma with therapeutic implications.

Sheng Z, Li L, Zhu LJ, Smith TW, Demers A, Ross AH, Moser RP, Green MR.

Nat Med. 2010 Jun;16(6):671-7. doi: 10.1038/nm.2158. Epub 2010 May 23.

10.

Downregulation of activating transcription factor 5 is required for differentiation of neural progenitor cells into astrocytes.

Angelastro JM, Mason JL, Ignatova TN, Kukekov VG, Stengren GB, Goldman JE, Greene LA.

J Neurosci. 2005 Apr 13;25(15):3889-99.

11.
12.

ATF5 increases cisplatin-induced apoptosis through up-regulation of cyclin D3 transcription in HeLa cells.

Wei Y, Jiang J, Sun M, Chen X, Wang H, Gu J.

Biochem Biophys Res Commun. 2006 Jan 13;339(2):591-6. Epub 2005 Nov 17.

PMID:
16300731
13.

Overexpression of BCL-X(L) underlies the molecular basis for resistance to staurosporine-induced apoptosis in PC-3 cells.

Li X, Marani M, Mannucci R, Kinsey B, Andriani F, Nicoletti I, Denner L, Marcelli M.

Cancer Res. 2001 Feb 15;61(4):1699-706.

14.

Oxidative stress-mediated down-regulation of bcl-2 promoter in hippocampal neurons.

Pugazhenthi S, Nesterova A, Jambal P, Audesirk G, Kern M, Cabell L, Eves E, Rosner MR, Boxer LM, Reusch JE.

J Neurochem. 2003 Mar;84(5):982-96.

15.

Regulation of the human CHOP gene promoter by the stress response transcription factor ATF5 via the AARE1 site in human hepatoma HepG2 cells.

Yamazaki T, Ohmi A, Kurumaya H, Kato K, Abe T, Yamamoto H, Nakanishi N, Okuyama R, Umemura M, Kaise T, Watanabe R, Okawa Y, Takahashi S, Takahashi Y.

Life Sci. 2010 Aug 28;87(9-10):294-301. doi: 10.1016/j.lfs.2010.07.006. Epub 2010 Jul 21.

PMID:
20654631
16.

The hepatitis B virus-X protein activates a phosphatidylinositol 3-kinase-dependent survival signaling cascade.

Lee YI, Kang-Park S, Do SI, Lee YI.

J Biol Chem. 2001 May 18;276(20):16969-77. Epub 2001 Mar 1.

17.

The endoplasmic reticulum stress transducer BBF2H7 suppresses apoptosis by activating the ATF5-MCL1 pathway in growth plate cartilage.

Izumi S, Saito A, Kanemoto S, Kawasaki N, Asada R, Iwamoto H, Oki M, Miyagi H, Ochi M, Imaizumi K.

J Biol Chem. 2012 Oct 19;287(43):36190-200. doi: 10.1074/jbc.M112.373746. Epub 2012 Aug 30.

18.

Small inhibitor of Bcl-2, HA14-1, selectively enhanced the apoptotic effect of cisplatin by modulating Bcl-2 family members in MDA-MB-231 breast cancer cells.

Arisan ED, Kutuk O, Tezil T, Bodur C, Telci D, Basaga H.

Breast Cancer Res Treat. 2010 Jan;119(2):271-81. doi: 10.1007/s10549-009-0343-z. Epub 2009 Feb 24.

PMID:
19238538
19.

Identification and characterization of the promoter of human ATF5 gene.

Wei Y, Ge Y, Zhou F, Chen H, Cui C, Liu D, Yang Z, Wu G, Gu J, Jiang J.

J Biochem. 2010 Aug;148(2):171-8. doi: 10.1093/jb/mvq047. Epub 2010 Apr 27.

PMID:
20423929
20.

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