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Items: 1 to 20 of 227

1.

Determination of the nicotine metabolites cotinine and trans-3'-hydroxycotinine in biologic fluids of smokers and non-smokers using liquid chromatography-tandem mass spectrometry: biomarkers for tobacco smoke exposure and for phenotyping cytochrome P450 2A6 activity.

Jacob P 3rd, Yu L, Duan M, Ramos L, Yturralde O, Benowitz NL.

J Chromatogr B Analyt Technol Biomed Life Sci. 2011 Feb 1;879(3-4):267-76. doi: 10.1016/j.jchromb.2010.12.012. Epub 2010 Dec 21.

3.

CYP2A6 genotype, phenotype, and the use of nicotine metabolites as biomarkers during ad libitum smoking.

Malaiyandi V, Goodz SD, Sellers EM, Tyndale RF.

Cancer Epidemiol Biomarkers Prev. 2006 Oct;15(10):1812-9.

4.

Characterization of multiple products of cytochrome P450 2A6-catalyzed cotinine metabolism.

Murphy SE, Johnson LM, Pullo DA.

Chem Res Toxicol. 1999 Jul;12(7):639-45.

PMID:
10409404
5.

Biomarkers of secondhand smoke exposure in automobiles.

Jones IA, St Helen G, Meyers MJ, Dempsey DA, Havel C, Jacob P 3rd, Northcross A, Hammond SK, Benowitz NL.

Tob Control. 2014 Jan;23(1):51-7. doi: 10.1136/tobaccocontrol-2012-050724. Epub 2013 Jan 24.

6.

Biomonitoring of urinary cotinine concentrations associated with plasma levels of nicotine metabolites after daily cigarette smoking in a male Japanese population.

Nagano T, Shimizu M, Kiyotani K, Kamataki T, Takano R, Murayama N, Shono F, Yamazaki H.

Int J Environ Res Public Health. 2010 Jul;7(7):2953-64. doi: 10.3390/ijerph7072953. Epub 2010 Jul 20.

7.

Urinary biomarkers for secondhand smoke.

Ino T, Ohtani T, Yoshimi I.

J Clin Lab Anal. 2011;25(5):354-8. doi: 10.1002/jcla.20485.

PMID:
21919071
8.

Nicotine metabolite ratio as an index of cytochrome P450 2A6 metabolic activity.

Dempsey D, Tutka P, Jacob P 3rd, Allen F, Schoedel K, Tyndale RF, Benowitz NL.

Clin Pharmacol Ther. 2004 Jul;76(1):64-72.

PMID:
15229465
9.

Nicotine Metabolism and Smoking: Ethnic Differences in the Role of P450 2A6.

Murphy SE.

Chem Res Toxicol. 2017 Jan 17;30(1):410-419. doi: 10.1021/acs.chemrestox.6b00387. Epub 2016 Nov 22.

PMID:
28092945
10.

Cotinine and trans 3'-hydroxycotinine in dried blood spots as biomarkers of tobacco exposure and nicotine metabolism.

Murphy SE, Wickham KM, Lindgren BR, Spector LG, Joseph A.

J Expo Sci Environ Epidemiol. 2013 Sep-Oct;23(5):513-8. doi: 10.1038/jes.2013.7. Epub 2013 Feb 27.

11.
13.

Simultaneous and sensitive measurement of nicotine, cotinine, trans-3'-hydroxycotinine and norcotinine in human plasma by liquid chromatography-tandem mass spectrometry.

Shakleya DM, Huestis MA.

J Chromatogr B Analyt Technol Biomed Life Sci. 2009 Nov 1;877(29):3537-42. doi: 10.1016/j.jchromb.2009.08.033. Epub 2009 Aug 28.

14.

Nicotine intake and smoking topography in smokers with bipolar disorder.

Williams JM, Gandhi KK, Lu SE, Steinberg ML, Benowitz NL.

Bipolar Disord. 2012 Sep;14(6):618-27. doi: 10.1111/j.1399-5618.2012.01047.x.

15.
16.

A LC-MS/MS method for concurrent determination of nicotine metabolites and role of CYP2A6 in nicotine metabolism in U937 macrophages: implications in oxidative stress in HIV + smokers.

Jin M, Earla R, Shah A, Earla RL, Gupte R, Mitra AK, Kumar A, Kumar S.

J Neuroimmune Pharmacol. 2012 Mar;7(1):289-99. doi: 10.1007/s11481-011-9283-6. Epub 2011 Jun 8.

17.

High-throughput wide dynamic range procedure for the simultaneous quantification of nicotine and cotinine in multiple biological matrices using hydrophilic interaction liquid chromatography-tandem mass spectrometry.

Pérez-Ortuño R, Martínez-Sánchez JM, Fernández E, Pascual JA.

Anal Bioanal Chem. 2015 Nov;407(28):8463-73. doi: 10.1007/s00216-015-8993-7. Epub 2015 Sep 5.

PMID:
26342312
18.

Estimation of nicotine dose after low-level exposure using plasma and urine nicotine metabolites.

Benowitz NL, Dains KM, Dempsey D, Yu L, Jacob P 3rd.

Cancer Epidemiol Biomarkers Prev. 2010 May;19(5):1160-6. doi: 10.1158/1055-9965.EPI-09-1303.

19.

Detection of tobacco-related biomarkers in urine samples by surface-enhanced Raman spectroscopy coupled with thin-layer chromatography.

Huang R, Han S, Li XS.

Anal Bioanal Chem. 2013 Aug;405(21):6815-22. doi: 10.1007/s00216-013-7107-7. Epub 2013 Jun 27.

PMID:
23807309
20.

Effects of watercress consumption on urinary metabolites of nicotine in smokers.

Hecht SS, Carmella SG, Murphy SE.

Cancer Epidemiol Biomarkers Prev. 1999 Oct;8(10):907-13.

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