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Items: 1 to 20 of 89

1.

Tn glycosylation of the MUC6 protein modulates its immunogenicity and promotes the induction of Th17-biased T cell responses.

Freire T, Lo-Man R, Bay S, Leclerc C.

J Biol Chem. 2011 Mar 11;286(10):7797-811. doi: 10.1074/jbc.M110.209742. Epub 2010 Dec 30.

2.

Enzymatic large-scale synthesis of MUC6-Tn glycoconjugates for antitumor vaccination.

Freire T, Lo-Man R, Piller F, Piller V, Leclerc C, Bay S.

Glycobiology. 2006 May;16(5):390-401. Epub 2006 Jan 31.

PMID:
16449349
3.

Molecular basis of incomplete O-glycan synthesis in MCF-7 breast cancer cells: putative role of MUC6 in Tn antigen expression.

Freire T, Bay S, von Mensdorff-Pouilly S, Osinaga E.

Cancer Res. 2005 Sep 1;65(17):7880-7.

4.
6.

Mucin 6 and Tn antigen expression in canine mammary tumours: correlation with pathological features.

Tavares C, de Oliveira JT, Lopes C, Carvalheira J, Matos AJ, Rutteman G, Reis CA, Gärtner F.

J Comp Pathol. 2012 Nov;147(4):410-8. doi: 10.1016/j.jcpa.2012.03.007. Epub 2012 May 15.

PMID:
22595635
7.

Glycan elongation beyond the mucin associated Tn antigen protects tumor cells from immune-mediated killing.

Madsen CB, Lavrsen K, Steentoft C, Vester-Christensen MB, Clausen H, Wandall HH, Pedersen AE.

PLoS One. 2013 Sep 6;8(9):e72413. doi: 10.1371/journal.pone.0072413. eCollection 2013. Erratum in: PLoS One. 2013;8(10). doi:10.1371/annotation/81b54c99-e47f-4128-8aeb-b6b3e8c02562.

8.

Anti-tumor immunity provided by a synthetic multiple antigenic glycopeptide displaying a tri-Tn glycotope.

Lo-Man R, Vichier-Guerre S, Bay S, Dériaud E, Cantacuzène D, Leclerc C.

J Immunol. 2001 Feb 15;166(4):2849-54.

9.

Glycosidic Tn-based vaccines targeting dermal dendritic cells favor germinal center B-cell development and potent antibody response in the absence of adjuvant.

Freire T, Zhang X, Dériaud E, Ganneau C, Vichier-Guerre S, Azria E, Launay O, Lo-Man R, Bay S, Leclerc C.

Blood. 2010 Nov 4;116(18):3526-36. doi: 10.1182/blood-2010-04-279133. Epub 2010 Aug 18.

10.

Mucin-type O-glycosylation in Mesocestoides vogae (syn. corti).

Medeiros A, Chiribao ML, Ubillos L, Festari MF, Saldaña J, Robello C, Domínguez L, Calvete JJ, Osinaga E.

Int J Parasitol. 2008 Mar;38(3-4):265-76. Epub 2007 Aug 14.

PMID:
17892882
11.

Expression of Tn, sialosyl-Tn, and T antigens in human colon cancer.

Itzkowitz SH, Yuan M, Montgomery CK, Kjeldsen T, Takahashi HK, Bigbee WL, Kim YS.

Cancer Res. 1989 Jan 1;49(1):197-204.

12.

Short synthetic glycopeptides successfully induce antibody responses to carcinoma-associated Tn antigen.

Vichier-Guerre S, Lo-Man R, Bay S, Deriaud E, Nakada H, Leclerc C, Cantacuzène D.

J Pept Res. 2000 Feb;55(2):173-80.

PMID:
10784033
14.

Monoclonal antibodies toward different Tn-amino acid backbones display distinct recognition patterns on human cancer cells. Implications for effective immuno-targeting of cancer.

Mazal D, Lo-Man R, Bay S, Pritsch O, Dériaud E, Ganneau C, Medeiros A, Ubillos L, Obal G, Berois N, Bollati-Fogolin M, Leclerc C, Osinaga E.

Cancer Immunol Immunother. 2013 Jun;62(6):1107-22. doi: 10.1007/s00262-013-1425-7. Epub 2013 Apr 21.

PMID:
23604173
15.
16.

Biochemical characterization of soluble Tn glycoproteins from malignant effusions of patients with carcinomas.

Freire T, Medeiros A, Reis CA, Real FX, Osinaga E.

Oncol Rep. 2003 Sep-Oct;10(5):1577-85.

PMID:
12883744
17.

Analysis of a heterogeneous group of human breast carcinoma associated glycoproteins bearing the Tn determinant.

Osinaga E, Pancino G, Porchet N, Berois N, De Cremoux P, Mistro D, Aubert JP, Calvo F, Roseto A.

Breast Cancer Res Treat. 1994;32(2):139-52.

PMID:
7532464
18.

The C-type lectin MGL expressed by dendritic cells detects glycan changes on MUC1 in colon carcinoma.

Saeland E, van Vliet SJ, Bäckström M, van den Berg VC, Geijtenbeek TB, Meijer GA, van Kooyk Y.

Cancer Immunol Immunother. 2007 Aug;56(8):1225-36. Epub 2006 Dec 29.

PMID:
17195076
19.
20.

The characterization of the first anti-mouse Muc6 antibody shows an increased expression of the mucin in pancreatic tissue of Cftr-knockout mice.

Gouyer V, Leir SH, Tetaert D, Liu Y, Gottrand F, Harris A, Desseyn JL.

Histochem Cell Biol. 2010 May;133(5):517-25. doi: 10.1007/s00418-010-0688-8. Epub 2010 Mar 23.

PMID:
20309575

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