Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 171

1.

Rapid end-point quantitation of prion seeding activity with sensitivity comparable to bioassays.

Wilham JM, Orrú CD, Bessen RA, Atarashi R, Sano K, Race B, Meade-White KD, Taubner LM, Timmes A, Caughey B.

PLoS Pathog. 2010 Dec 2;6(12):e1001217. doi: 10.1371/journal.ppat.1001217.

2.

Prion seeding activities of mouse scrapie strains with divergent PrPSc protease sensitivities and amyloid plaque content using RT-QuIC and eQuIC.

Vascellari S, Orrù CD, Hughson AG, King D, Barron R, Wilham JM, Baron GS, Race B, Pani A, Caughey B.

PLoS One. 2012;7(11):e48969. doi: 10.1371/journal.pone.0048969. Epub 2012 Nov 5.

3.

Sensitive and specific detection of classical scrapie prions in the brains of goats by real-time quaking-induced conversion.

Dassanayake RP, Orrú CD, Hughson AG, Caughey B, Graça T, Zhuang D, Madsen-Bouterse SA, Knowles DP, Schneider DA.

J Gen Virol. 2016 Mar;97(3):803-12. doi: 10.1099/jgv.0.000367. Epub 2015 Dec 10.

PMID:
26653410
4.

New generation QuIC assays for prion seeding activity.

Orrù CD, Wilham JM, Vascellari S, Hughson AG, Caughey B.

Prion. 2012 Apr-Jun;6(2):147-52. doi: 10.4161/pri.19430. Epub 2012 Apr 1. Review.

PMID:
22421206
5.

Prion disease blood test using immunoprecipitation and improved quaking-induced conversion.

Orrú CD, Wilham JM, Raymond LD, Kuhn F, Schroeder B, Raeber AJ, Caughey B.

MBio. 2011 May 10;2(3):e00078-11. doi: 10.1128/mBio.00078-11. Print 2011.

6.

Factors That Improve RT-QuIC Detection of Prion Seeding Activity.

Orrú CD, Hughson AG, Groveman BR, Campbell KJ, Anson KJ, Manca M, Kraus A, Caughey B.

Viruses. 2016 May 23;8(5). pii: E140. doi: 10.3390/v8050140.

8.

Sensitive and specific detection of sporadic Creutzfeldt-Jakob disease brain prion protein using real-time quaking-induced conversion.

Peden AH, McGuire LI, Appleford NE, Mallinson G, Wilham JM, Orrú CD, Caughey B, Ironside JW, Knight RS, Will RG, Green AJ, Head MW.

J Gen Virol. 2012 Feb;93(Pt 2):438-49. doi: 10.1099/vir.0.033365-0. Epub 2011 Oct 26.

9.

Quantitative assessment of prion infectivity in tissues and body fluids by real-time quaking-induced conversion.

Henderson DM, Davenport KA, Haley NJ, Denkers ND, Mathiason CK, Hoover EA.

J Gen Virol. 2015 Jan;96(Pt 1):210-9. doi: 10.1099/vir.0.069906-0. Epub 2014 Oct 10.

10.

Human variant Creutzfeldt-Jakob disease and sheep scrapie PrP(res) detection using seeded conversion of recombinant prion protein.

Orrú CD, Wilham JM, Hughson AG, Raymond LD, McNally KL, Bossers A, Ligios C, Caughey B.

Protein Eng Des Sel. 2009 Aug;22(8):515-21. doi: 10.1093/protein/gzp031. Epub 2009 Jul 1.

11.

Bank Vole Prion Protein As an Apparently Universal Substrate for RT-QuIC-Based Detection and Discrimination of Prion Strains.

Orrú CD, Groveman BR, Raymond LD, Hughson AG, Nonno R, Zou W, Ghetti B, Gambetti P, Caughey B.

PLoS Pathog. 2015 Jun 18;11(6):e1004983. doi: 10.1371/journal.ppat.1004983. eCollection 2015 Jun. Erratum in: PLoS Pathog. 2015 Aug;11(8):e1005117.

12.

Amplified Detection of Prions and Other Amyloids by RT-QuIC in Diagnostics and the Evaluation of Therapeutics and Disinfectants.

Caughey B, Orru CD, Groveman BR, Hughson AG, Manca M, Raymond LD, Raymond GJ, Race B, Saijo E, Kraus A.

Prog Mol Biol Transl Sci. 2017;150:375-388. doi: 10.1016/bs.pmbts.2017.06.003. Epub 2017 Jul 27.

PMID:
28838670
13.

A test for Creutzfeldt-Jakob disease using nasal brushings.

Orrú CD, Bongianni M, Tonoli G, Ferrari S, Hughson AG, Groveman BR, Fiorini M, Pocchiari M, Monaco S, Caughey B, Zanusso G.

N Engl J Med. 2014 Aug 7;371(6):519-29. doi: 10.1056/NEJMoa1315200. Erratum in: N Engl J Med. 2014 Nov 6;371(19):1852.

14.

Real-time Quaking-induced Conversion Assay for Detection of CWD Prions in Fecal Material.

Cheng YC, Hannaoui S, John TR, Dudas S, Czub S, Gilch S.

J Vis Exp. 2017 Sep 29;(127). doi: 10.3791/56373.

PMID:
28994814
15.

Endogenous Brain Lipids Inhibit Prion Amyloid Formation In Vitro.

Hoover CE, Davenport KA, Henderson DM, Zabel MD, Hoover EA.

J Virol. 2017 Apr 13;91(9). pii: e02162-16. doi: 10.1128/JVI.02162-16. Print 2017 May 1.

16.

Sensitive detection of aggregated prion protein via proximity ligation.

Hammond M, Wik L, Deslys JP, Comoy E, Linné T, Landegren U, Kamali-Moghaddam M.

Prion. 2014;8(3):261-5. doi: 10.4161/pri.32231.

17.

Prion-seeding activity in cerebrospinal fluid of deer with chronic wasting disease.

Haley NJ, Van de Motter A, Carver S, Henderson D, Davenport K, Seelig DM, Mathiason C, Hoover E.

PLoS One. 2013 Nov 25;8(11):e81488. doi: 10.1371/journal.pone.0081488. eCollection 2013.

18.

Establishing quantitative real-time quaking-induced conversion (qRT-QuIC) for highly sensitive detection and quantification of PrPSc in prion-infected tissues.

Shi S, Mitteregger-Kretzschmar G, Giese A, Kretzschmar HA.

Acta Neuropathol Commun. 2013 Aug 2;1:44. doi: 10.1186/2051-5960-1-44.

19.

Rapid and sensitive RT-QuIC detection of human Creutzfeldt-Jakob disease using cerebrospinal fluid.

Orrú CD, Groveman BR, Hughson AG, Zanusso G, Coulthart MB, Caughey B.

MBio. 2015 Jan 20;6(1). pii: e02451-14. doi: 10.1128/mBio.02451-14.

20.

RT-QuIC Assays for Prion Disease Detection and Diagnostics.

Orrù CD, Groveman BR, Hughson AG, Manca M, Raymond LD, Raymond GJ, Campbell KJ, Anson KJ, Kraus A, Caughey B.

Methods Mol Biol. 2017;1658:185-203. doi: 10.1007/978-1-4939-7244-9_14.

PMID:
28861791

Supplemental Content

Support Center