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Development and function of CD94-deficient natural killer cells.

Orr MT, Wu J, Fang M, Sigal LJ, Spee P, Egebjerg T, Dissen E, Fossum S, Phillips JH, Lanier LL.

PLoS One. 2010 Dec 3;5(12):e15184. doi: 10.1371/journal.pone.0015184.


Rat and mouse CD94 associate directly with the activating transmembrane adaptor proteins DAP12 and DAP10 and activate NK cell cytotoxicity.

Saether PC, Hoelsbrekken SE, Fossum S, Dissen E.

J Immunol. 2011 Dec 15;187(12):6365-73. doi: 10.4049/jimmunol.1102345. Epub 2011 Nov 14.


Expansion of CD94/NKG2C+ NK cells in response to human cytomegalovirus-infected fibroblasts.

Gumá M, Budt M, Sáez A, Brckalo T, Hengel H, Angulo A, López-Botet M.

Blood. 2006 May 1;107(9):3624-31. Epub 2005 Dec 29.


Orderly and nonstochastic acquisition of CD94/NKG2 receptors by developing NK cells derived from embryonic stem cells in vitro.

Lian RH, Maeda M, Lohwasser S, Delcommenne M, Nakano T, Vance RE, Raulet DH, Takei F.

J Immunol. 2002 May 15;168(10):4980-7.


IL-12-dependent inducible expression of the CD94/NKG2A inhibitory receptor regulates CD94/NKG2C+ NK cell function.

Sáez-Borderías A, Romo N, Magri G, Gumá M, Angulo A, López-Botet M.

J Immunol. 2009 Jan 15;182(2):829-36.


Calcineurin-dependent negative regulation of CD94/NKG2A expression on naive CD8+ T cells.

Cho JH, Kim HO, Webster K, Palendira M, Hahm B, Kim KS, King C, Tangye SG, Sprent J.

Blood. 2011 Jul 7;118(1):116-28. doi: 10.1182/blood-2010-11-317396. Epub 2011 May 3.


Polymorphism in human cytomegalovirus UL40 impacts on recognition of human leukocyte antigen-E (HLA-E) by natural killer cells.

Heatley SL, Pietra G, Lin J, Widjaja JM, Harpur CM, Lester S, Rossjohn J, Szer J, Schwarer A, Bradstock K, Bardy PG, Mingari MC, Moretta L, Sullivan LC, Brooks AG.

J Biol Chem. 2013 Mar 22;288(12):8679-90. doi: 10.1074/jbc.M112.409672. Epub 2013 Jan 18.


Viral and bacterial infections induce expression of multiple NK cell receptors in responding CD8(+) T cells.

McMahon CW, Zajac AJ, Jamieson AM, Corral L, Hammer GE, Ahmed R, Raulet DH.

J Immunol. 2002 Aug 1;169(3):1444-52.


Increased frequency of human leukocyte antigen-E inhibitory receptor CD94/NKG2A-expressing peritoneal natural killer cells in patients with endometriosis.

Galandrini R, Porpora MG, Stoppacciaro A, Micucci F, Capuano C, Tassi I, Di Felice A, Benedetti-Panici P, Santoni A.

Fertil Steril. 2008 May;89(5 Suppl):1490-6. Epub 2007 Aug 13.


Differential expression of NK receptors CD94 and NKG2A by T cells in rheumatoid arthritis patients in remission compared to active disease.

Walsh CE, Ryan EJ, O'Farrelly C, Golden-Mason L, FitzGerald O, Veale DJ, Bresnihan B, Fearon U.

PLoS One. 2011;6(11):e27182. doi: 10.1371/journal.pone.0027182. Epub 2011 Nov 15.


Downregulation of CD94/NKG2A inhibitory receptors on CD8+ T cells in HIV infection is more pronounced in subjects with detected viral load than in their aviraemic counterparts.

Zeddou M, Rahmouni S, Vandamme A, Jacobs N, Frippiat F, Leonard P, Schaaf-Lafontaine N, Vaira D, Boniver J, Moutschen M.

Retrovirology. 2007 Oct 10;4:72.


Upregulation of Fas and downregulation of CD94/NKG2A inhibitory receptors on circulating natural killer cells in patients with new-onset psoriasis.

Son SW, Kim EO, Ryu ES, Kim TJ, Kim JN, Choi JE, Kye YC, Lee KM.

Br J Dermatol. 2009 Aug;161(2):281-8. doi: 10.1111/j.1365-2133.2009.09178.x. Epub 2009 Apr 29.


Low gene expression levels of activating receptors of natural killer cells (NKG2E and CD94) in patients with fulminant type 1 diabetes.

Nakata S, Imagawa A, Miyata Y, Yoshikawa A, Kozawa J, Okita K, Funahashi T, Nakamura S, Matsubara K, Iwahashi H, Shimomura I.

Immunol Lett. 2013 Nov-Dec;156(1-2):149-55. doi: 10.1016/j.imlet.2013.10.004. Epub 2013 Oct 25.


The CD94/NKG2C+ NK-cell subset on the edge of innate and adaptive immunity to human cytomegalovirus infection.

López-Botet M, Muntasell A, Vilches C.

Semin Immunol. 2014 Apr;26(2):145-51. doi: 10.1016/j.smim.2014.03.002. Epub 2014 Mar 22. Review.


The CD94/NKG2C killer lectin-like receptor constitutes an alternative activation pathway for a subset of CD8+ T cells.

Gumá M, Busch LK, Salazar-Fontana LI, Bellosillo B, Morte C, García P, López-Botet M.

Eur J Immunol. 2005 Jul;35(7):2071-80. Erratum in: Eur J Immunol. 2005 Jul;35(7):2259.


Preferential survival of CD8 T and NK cells expressing high levels of CD94.

Gunturi A, Berg RE, Forman J.

J Immunol. 2003 Feb 15;170(4):1737-45.


Expression of Ly49E and CD94/NKG2 on fetal and adult NK cells.

Van Beneden K, Stevenaert F, De Creus A, Debacker V, De Boever J, Plum J, Leclercq G.

J Immunol. 2001 Apr 1;166(7):4302-11.


CD94/NKG2 expression does not inhibit cytotoxic function of lymphocytic choriomeningitis virus-specific CD8+ T cells.

Miller JD, Peters M, Oran AE, Beresford GW, Harrington L, Boss JM, Altman JD.

J Immunol. 2002 Jul 15;169(2):693-701.


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