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Items: 1 to 20 of 154

1.

Polycystic kidney disease: pathogenesis and potential therapies.

Takiar V, Caplan MJ.

Biochim Biophys Acta. 2011 Oct;1812(10):1337-43. doi: 10.1016/j.bbadis.2010.11.014. Epub 2010 Dec 10. Review.

2.

Autosomal dominant polycystic kidney disease: recent advances in pathogenesis and potential therapies.

Mochizuki T, Tsuchiya K, Nitta K.

Clin Exp Nephrol. 2013 Jun;17(3):317-26. doi: 10.1007/s10157-012-0741-0. Epub 2012 Nov 29. Review.

PMID:
23192769
3.

Fluid transport and cystogenesis in autosomal dominant polycystic kidney disease.

Terryn S, Ho A, Beauwens R, Devuyst O.

Biochim Biophys Acta. 2011 Oct;1812(10):1314-21. doi: 10.1016/j.bbadis.2011.01.011. Epub 2011 Jan 19. Review.

4.

Fibrosis and progression of autosomal dominant polycystic kidney disease (ADPKD).

Norman J.

Biochim Biophys Acta. 2011 Oct;1812(10):1327-36. doi: 10.1016/j.bbadis.2011.06.012. Epub 2011 Jul 1. Review.

5.

Regulation of ciliary trafficking of polycystin-2 and the pathogenesis of autosomal dominant polycystic kidney disease.

Cai Y, Tang Z.

Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2010 Feb;35(2):93-9. doi: 10.3969/j.issn.1672-7347.2010.02.001. Review.

6.

Molecular pathways and therapies in autosomal-dominant polycystic kidney disease.

Saigusa T, Bell PD.

Physiology (Bethesda). 2015 May;30(3):195-207. doi: 10.1152/physiol.00032.2014. Review.

7.

Molecular advances in autosomal dominant polycystic kidney disease.

Gallagher AR, Germino GG, Somlo S.

Adv Chronic Kidney Dis. 2010 Mar;17(2):118-30. doi: 10.1053/j.ackd.2010.01.002. Review.

8.

The pathogenesis of autosomal dominant polycystic kidney disease.

Sutters M.

Nephron Exp Nephrol. 2006;103(4):e149-55. Epub 2006 May 10. Review.

9.

Loss of polycystin-1 in human cyst-lining epithelia leads to ciliary dysfunction.

Nauli SM, Rossetti S, Kolb RJ, Alenghat FJ, Consugar MB, Harris PC, Ingber DE, Loghman-Adham M, Zhou J.

J Am Soc Nephrol. 2006 Apr;17(4):1015-25.

10.

Does TNF-alpha enhance cystogenesis in ADPKD?

Pirson Y.

Nephrol Dial Transplant. 2008 Dec;23(12):3773-5. doi: 10.1093/ndt/gfn533. Epub 2008 Sep 26. Review. No abstract available.

PMID:
18820281
11.

Increased expression of secreted frizzled-related protein 4 in polycystic kidneys.

Romaker D, Puetz M, Teschner S, Donauer J, Geyer M, Gerke P, Rumberger B, Dworniczak B, Pennekamp P, Buchholz B, Neumann HP, Kumar R, Gloy J, Eckardt KU, Walz G.

J Am Soc Nephrol. 2009 Jan;20(1):48-56. doi: 10.1681/ASN.2008040345. Epub 2008 Oct 22.

12.

The Jeremiah Metzger Lecture. Polycystic kidney disease: old disease in a new context.

Grantham JJ.

Trans Am Clin Climatol Assoc. 2002;113:211-24; discussion 224-6.

13.

Genetic Mechanisms of ADPKD.

Kim DY, Park JH.

Adv Exp Med Biol. 2016;933:13-22. Review.

PMID:
27730431
14.

Inhibiting the HSP90 chaperone slows cyst growth in a mouse model of autosomal dominant polycystic kidney disease.

Seeger-Nukpezah T, Proia DA, Egleston BL, Nikonova AS, Kent T, Cai KQ, Hensley HH, Ying W, Chimmanamada D, Serebriiskii IG, Golemis EA.

Proc Natl Acad Sci U S A. 2013 Jul 30;110(31):12786-91. doi: 10.1073/pnas.1301904110. Epub 2013 Jul 15.

15.

Epigenetics and autosomal dominant polycystic kidney disease.

Li X.

Biochim Biophys Acta. 2011 Oct;1812(10):1213-8. doi: 10.1016/j.bbadis.2010.10.008. Epub 2010 Oct 20. Review.

16.

The cell biology of polycystic kidney disease.

Chapin HC, Caplan MJ.

J Cell Biol. 2010 Nov 15;191(4):701-10. doi: 10.1083/jcb.201006173. Review.

17.

Development of polycystic kidney disease in juvenile cystic kidney mice: insights into pathogenesis, ciliary abnormalities, and common features with human disease.

Smith LA, Bukanov NO, Husson H, Russo RJ, Barry TC, Taylor AL, Beier DR, Ibraghimov-Beskrovnaya O.

J Am Soc Nephrol. 2006 Oct;17(10):2821-31. Epub 2006 Aug 23.

18.

Nedd9 restrains renal cystogenesis in Pkd1-/- mice.

Nikonova AS, Plotnikova OV, Serzhanova V, Efimov A, Bogush I, Cai KQ, Hensley HH, Egleston BL, Klein-Szanto A, Seeger-Nukpezah T, Golemis EA.

Proc Natl Acad Sci U S A. 2014 Sep 2;111(35):12859-64. doi: 10.1073/pnas.1405362111. Epub 2014 Aug 19.

19.

New insights into the molecular pathophysiology of polycystic kidney disease.

Murcia NS, Sweeney WE Jr, Avner ED.

Kidney Int. 1999 Apr;55(4):1187-97. Review.

20.

Scattered Deletion of PKD1 in Kidneys Causes a Cystic Snowball Effect and Recapitulates Polycystic Kidney Disease.

Leonhard WN, Zandbergen M, Veraar K, van den Berg S, van der Weerd L, Breuning M, de Heer E, Peters DJ.

J Am Soc Nephrol. 2015 Jun;26(6):1322-33. doi: 10.1681/ASN.2013080864. Epub 2014 Oct 31.

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