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RNA induces conformational changes in the SF1/U2AF65 splicing factor complex.

Gupta A, Jenkins JL, Kielkopf CL.

J Mol Biol. 2011 Feb 4;405(5):1128-38. doi: 10.1016/j.jmb.2010.11.054. Epub 2010 Dec 10.


Structure, phosphorylation and U2AF65 binding of the N-terminal domain of splicing factor 1 during 3'-splice site recognition.

Zhang Y, Madl T, Bagdiul I, Kern T, Kang HS, Zou P, Mäusbacher N, Sieber SA, Krämer A, Sattler M.

Nucleic Acids Res. 2013 Jan;41(2):1343-54. doi: 10.1093/nar/gks1097. Epub 2012 Nov 21.


Multiple U2AF65 binding sites within SF3b155: thermodynamic and spectroscopic characterization of protein-protein interactions among pre-mRNA splicing factors.

Thickman KR, Swenson MC, Kabogo JM, Gryczynski Z, Kielkopf CL.

J Mol Biol. 2006 Feb 24;356(3):664-83. Epub 2005 Dec 7.


Structure of phosphorylated SF1 bound to U2AF⁶⁵ in an essential splicing factor complex.

Wang W, Maucuer A, Gupta A, Manceau V, Thickman KR, Bauer WJ, Kennedy SD, Wedekind JE, Green MR, Kielkopf CL.

Structure. 2013 Feb 5;21(2):197-208. doi: 10.1016/j.str.2012.10.020. Epub 2012 Dec 27.


Splicing factors SF1 and U2AF associate in extraspliceosomal complexes.

Rino J, Desterro JM, Pacheco TR, Gadella TW Jr, Carmo-Fonseca M.

Mol Cell Biol. 2008 May;28(9):3045-57. doi: 10.1128/MCB.02015-07. Epub 2008 Feb 19.


Mammalian splicing factor SF1 interacts with SURP domains of U2 snRNP-associated proteins.

Crisci A, Raleff F, Bagdiul I, Raabe M, Urlaub H, Rain JC, Krämer A.

Nucleic Acids Res. 2015 Dec 2;43(21):10456-73. doi: 10.1093/nar/gkv952. Epub 2015 Sep 29.


Solution conformation and thermodynamic characteristics of RNA binding by the splicing factor U2AF65.

Jenkins JL, Shen H, Green MR, Kielkopf CL.

J Biol Chem. 2008 Nov 28;283(48):33641-9. doi: 10.1074/jbc.M806297200. Epub 2008 Oct 8.


Pre-spliceosome formation in S.pombe requires a stable complex of SF1-U2AF(59)-U2AF(23).

Huang T, Vilardell J, Query CC.

EMBO J. 2002 Oct 15;21(20):5516-26.


An extended U2AF(65)-RNA-binding domain recognizes the 3' splice site signal.

Agrawal AA, Salsi E, Chatrikhi R, Henderson S, Jenkins JL, Green MR, Ermolenko DN, Kielkopf CL.

Nat Commun. 2016 Mar 8;7:10950. doi: 10.1038/ncomms10950.


Phosphorylation of splicing factor SF1 on Ser20 by cGMP-dependent protein kinase regulates spliceosome assembly.

Wang X, Bruderer S, Rafi Z, Xue J, Milburn PJ, Krämer A, Robinson PJ.

EMBO J. 1999 Aug 16;18(16):4549-59.


Dimerization and protein binding specificity of the U2AF homology motif of the splicing factor Puf60.

Corsini L, Hothorn M, Stier G, Rybin V, Scheffzek K, Gibson TJ, Sattler M.

J Biol Chem. 2009 Jan 2;284(1):630-9. doi: 10.1074/jbc.M805395200. Epub 2008 Oct 29.


hnRNP A1 proofreads 3' splice site recognition by U2AF.

Tavanez JP, Madl T, Kooshapur H, Sattler M, Valcárcel J.

Mol Cell. 2012 Feb 10;45(3):314-29. doi: 10.1016/j.molcel.2011.11.033.


Prp40 pre-mRNA processing factor 40 homolog B (PRPF40B) associates with SF1 and U2AF65 and modulates alternative pre-mRNA splicing in vivo.

Becerra S, Montes M, Hernández-Munain C, Suñé C.

RNA. 2015 Mar;21(3):438-57. doi: 10.1261/rna.047258.114. Epub 2015 Jan 20.


U2AF65 adapts to diverse pre-mRNA splice sites through conformational selection of specific and promiscuous RNA recognition motifs.

Jenkins JL, Agrawal AA, Gupta A, Green MR, Kielkopf CL.

Nucleic Acids Res. 2013 Apr 1;41(6):3859-73. doi: 10.1093/nar/gkt046. Epub 2013 Feb 1.


Multi-domain conformational selection underlies pre-mRNA splicing regulation by U2AF.

Mackereth CD, Madl T, Bonnal S, Simon B, Zanier K, Gasch A, Rybin V, Valcárcel J, Sattler M.

Nature. 2011 Jul 13;475(7356):408-11. doi: 10.1038/nature10171.


Analysis of in situ pre-mRNA targets of human splicing factor SF1 reveals a function in alternative splicing.

Corioni M, Antih N, Tanackovic G, Zavolan M, Krämer A.

Nucleic Acids Res. 2011 Mar;39(5):1868-79. doi: 10.1093/nar/gkq1042. Epub 2010 Nov 9.

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