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Items: 1 to 20 of 88

1.

JNK1 controls mast cell degranulation and IL-1{beta} production in inflammatory arthritis.

Guma M, Kashiwakura J, Crain B, Kawakami Y, Beutler B, Firestein GS, Kawakami T, Karin M, Corr M.

Proc Natl Acad Sci U S A. 2010 Dec 21;107(51):22122-7. doi: 10.1073/pnas.1016401107. Epub 2010 Dec 6.

2.

c-Jun N-terminal kinase-1 from hematopoietic cells mediates progression from hepatic steatosis to steatohepatitis and fibrosis in mice.

Kodama Y, Kisseleva T, Iwaisako K, Miura K, Taura K, De Minicis S, Osterreicher CH, Schnabl B, Seki E, Brenner DA.

Gastroenterology. 2009 Oct;137(4):1467-1477.e5. doi: 10.1053/j.gastro.2009.06.045. Epub 2009 Jun 21.

4.

Redundant roles for cJun-N-terminal kinase 1 and 2 in interleukin-1beta-mediated reduction and modification of murine hepatic nuclear retinoid X receptor alpha.

Kosters A, White DD, Sun H, Thevananther S, Karpen SJ.

J Hepatol. 2009 Nov;51(5):898-908. doi: 10.1016/j.jhep.2009.06.029. Epub 2009 Aug 20.

5.

IL-1 beta induces urokinase-plasminogen activator expression and cell migration through PKC alpha, JNK1/2, and NF-kappaB in A549 cells.

Cheng CY, Hsieh HL, Sun CC, Lin CC, Luo SF, Yang CM.

J Cell Physiol. 2009 Apr;219(1):183-93. doi: 10.1002/jcp.21669.

PMID:
19097143
6.

JNK1 Deficient Insulin-Producing Cells Are Protected against Interleukin-1β-Induced Apoptosis Associated with Abrogated Myc Expression.

Prause M, Mayer CM, Brorsson C, Frederiksen KS, Billestrup N, Størling J, Mandrup-Poulsen T.

J Diabetes Res. 2016;2016:1312705. doi: 10.1155/2016/1312705. Epub 2016 Jan 10.

7.

JNK1, but not JNK2, is required in two mechanistically distinct models of inflammatory arthritis.

Denninger K, Rasmussen S, Larsen JM, Orskov C, Seier Poulsen S, Sørensen P, Christensen JP, Illges H, Odum N, Labuda T.

Am J Pathol. 2011 Oct;179(4):1884-93. doi: 10.1016/j.ajpath.2011.06.019. Epub 2011 Aug 11.

8.

JNK1 is not essential for TNF-mediated joint disease.

Köller M, Hayer S, Redlich K, Ricci R, David JP, Steiner G, Smolen JS, Wagner EF, Schett G.

Arthritis Res Ther. 2005;7(1):R166-73. Epub 2004 Dec 7.

9.

JNK1/2 regulates ER-mitochondrial Ca2+ cross-talk during IL-1β-mediated cell death in RINm5F and human primary β-cells.

Verma G, Bhatia H, Datta M.

Mol Biol Cell. 2013 Jun;24(12):2058-71. doi: 10.1091/mbc.E12-12-0885. Epub 2013 Apr 24.

11.

Inhibitory effects of extract from G. lanceolata on LPS-induced production of nitric oxide and IL-1β via down-regulation of MAPK in macrophages.

Kim DH, Kim ME, Lee JS.

Appl Biochem Biotechnol. 2015 Jan;175(2):657-65. doi: 10.1007/s12010-014-1301-8. Epub 2014 Oct 24.

PMID:
25342257
12.

Tyrosine phosphorylation of Vav stimulates IL-6 production in mast cells by a Rac/c-Jun N-terminal kinase-dependent pathway.

Song JS, Haleem-Smith H, Arudchandran R, Gomez J, Scott PM, Mill JF, Tan TH, Rivera J.

J Immunol. 1999 Jul 15;163(2):802-10.

13.

A pathogenic role for c-Jun amino-terminal kinase signaling in renal fibrosis and tubular cell apoptosis.

Ma FY, Flanc RS, Tesch GH, Han Y, Atkins RC, Bennett BL, Friedman GC, Fan JH, Nikolic-Paterson DJ.

J Am Soc Nephrol. 2007 Feb;18(2):472-84. Epub 2007 Jan 3.

14.

Bone marrow stromal cells inhibit mast cell function via a COX2-dependent mechanism.

Brown JM, Nemeth K, Kushnir-Sukhov NM, Metcalfe DD, Mezey E.

Clin Exp Allergy. 2011 Apr;41(4):526-34. doi: 10.1111/j.1365-2222.2010.03685.x. Epub 2011 Jan 24.

15.

Protection against cartilage and bone destruction by systemic interleukin-4 treatment in established murine type II collagen-induced arthritis.

Joosten LA, Lubberts E, Helsen MM, Saxne T, Coenen-de Roo CJ, Heinegård D, van den Berg WB.

Arthritis Res. 1999;1(1):81-91. Epub 1999 Oct 26.

16.

Structural requirements of SLP-76 in signaling via the high-affinity immunoglobulin E receptor (Fc epsilon RI) in mast cells.

Kettner A, Pivniouk V, Kumar L, Falet H, Lee JS, Mulligan R, Geha RS.

Mol Cell Biol. 2003 Apr;23(7):2395-406.

17.

Joint damage and inflammation in c-Jun N-terminal kinase 2 knockout mice with passive murine collagen-induced arthritis.

Han Z, Chang L, Yamanishi Y, Karin M, Firestein GS.

Arthritis Rheum. 2002 Mar;46(3):818-23.

18.

Interleukin (IL)-33 induces the release of pro-inflammatory mediators by mast cells.

Moulin D, Donzé O, Talabot-Ayer D, Mézin F, Palmer G, Gabay C.

Cytokine. 2007 Dec;40(3):216-25. Epub 2007 Nov 19.

PMID:
18023358
19.

c-Jun N-terminal kinase 1 is deleterious to the function and survival of murine pancreatic islets.

Varona-Santos JL, Pileggi A, Molano RD, Sanabria NY, Ijaz A, Atsushi M, Ichii H, Pastori RL, Inverardi L, Ricordi C, Fornoni A.

Diabetologia. 2008 Dec;51(12):2271-80. doi: 10.1007/s00125-008-1169-7. Epub 2008 Oct 14.

PMID:
18853132
20.

Blunted IgE-mediated activation of mast cells in mice lacking the Ca2+-activated K+ channel KCa3.1.

Shumilina E, Lam RS, Wölbing F, Matzner N, Zemtsova IM, Sobiesiak M, Mahmud H, Sausbier U, Biedermann T, Ruth P, Sausbier M, Lang F.

J Immunol. 2008 Jun 15;180(12):8040-7.

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