Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 72


Mechanical signal influence on mesenchymal stem cell fate is enhanced by incorporation of refractory periods into the loading regimen.

Sen B, Xie Z, Case N, Styner M, Rubin CT, Rubin J.

J Biomech. 2011 Feb 24;44(4):593-9. doi: 10.1016/j.jbiomech.2010.11.022. Epub 2010 Dec 4.


Mechanical loading regulates NFATc1 and beta-catenin signaling through a GSK3beta control node.

Sen B, Styner M, Xie Z, Case N, Rubin CT, Rubin J.

J Biol Chem. 2009 Dec 11;284(50):34607-17. doi: 10.1074/jbc.M109.039453. Epub 2009 Oct 19.


Mechanical stretch inhibits mesenchymal stem cell adipogenic differentiation through TGFβ1/Smad2 signaling.

Li R, Liang L, Dou Y, Huang Z, Mo H, Wang Y, Yu B.

J Biomech. 2015 Oct 15;48(13):3665-71. doi: 10.1016/j.jbiomech.2015.08.013. Epub 2015 Aug 21.


Mechanically induced focal adhesion assembly amplifies anti-adipogenic pathways in mesenchymal stem cells.

Sen B, Guilluy C, Xie Z, Case N, Styner M, Thomas J, Oguz I, Rubin C, Burridge K, Rubin J.

Stem Cells. 2011 Nov;29(11):1829-36. doi: 10.1002/stem.732.


Mechanical loading down-regulates peroxisome proliferator-activated receptor gamma in bone marrow stromal cells and favors osteoblastogenesis at the expense of adipogenesis.

David V, Martin A, Lafage-Proust MH, Malaval L, Peyroche S, Jones DB, Vico L, Guignandon A.

Endocrinology. 2007 May;148(5):2553-62. Epub 2007 Feb 22.


Evaluation of Mechanical and Chemical Stimulations on Osteocalcin and Runx2 Expression in Mesenchymal Stem Cells.

Jazayeri M, Shokrgozar MA, Haghighipour N, Mahdian R, Farrokhi M, Bonakdar S, Mirahmadi F, Abbariki TN.

Mol Cell Biomech. 2015 Sep;12(3):197-213.


Mechanically activated Fyn utilizes mTORC2 to regulate RhoA and adipogenesis in mesenchymal stem cells.

Thompson WR, Guilluy C, Xie Z, Sen B, Brobst KE, Yen SS, Uzer G, Styner M, Case N, Burridge K, Rubin J.

Stem Cells. 2013 Nov;31(11):2528-37. doi: 10.1002/stem.1476.


Adipogenesis is inhibited by brief, daily exposure to high-frequency, extremely low-magnitude mechanical signals.

Rubin CT, Capilla E, Luu YK, Busa B, Crawford H, Nolan DJ, Mittal V, Rosen CJ, Pessin JE, Judex S.

Proc Natl Acad Sci U S A. 2007 Nov 6;104(45):17879-84. Epub 2007 Oct 24.


Determination of mesenchymal stem cell fate by pigment epithelium-derived factor (PEDF) results in increased adiposity and reduced bone mineral content.

Gattu AK, Swenson ES, Iwakiri Y, Samuel VT, Troiano N, Berry R, Church CD, Rodeheffer MS, Carpenter TO, Chung C.

FASEB J. 2013 Nov;27(11):4384-94. doi: 10.1096/fj.13-232900. Epub 2013 Jul 25.


The omega-6 arachidonic fatty acid, but not the omega-3 fatty acids, inhibits osteoblastogenesis and induces adipogenesis of human mesenchymal stem cells: potential implication in osteoporosis.

Casado-Díaz A, Santiago-Mora R, Dorado G, Quesada-Gómez JM.

Osteoporos Int. 2013 May;24(5):1647-61. doi: 10.1007/s00198-012-2138-z. Epub 2012 Oct 27.


The effects of myostatin on adipogenic differentiation of human bone marrow-derived mesenchymal stem cells are mediated through cross-communication between Smad3 and Wnt/beta-catenin signaling pathways.

Guo W, Flanagan J, Jasuja R, Kirkland J, Jiang L, Bhasin S.

J Biol Chem. 2008 Apr 4;283(14):9136-45. doi: 10.1074/jbc.M708968200. Epub 2008 Jan 18.


Anti-adipogenic effects of sesamol on human mesenchymal stem cells.

Kim M, Lee YJ, Jee SC, Choi I, Sung JS.

Biochem Biophys Res Commun. 2016 Jan 1;469(1):49-54. doi: 10.1016/j.bbrc.2015.11.070. Epub 2015 Nov 23.


Mesenchymal stem cell and chondrocyte fates in a multishear microdevice are regulated by Yes-associated protein.

Zhong W, Tian K, Zheng X, Li L, Zhang W, Wang S, Qin J.

Stem Cells Dev. 2013 Jul 15;22(14):2083-93. doi: 10.1089/scd.2012.0685. Epub 2013 Apr 5.


Intrinsic and extrinsic mechanical properties related to the differentiation of mesenchymal stem cells.

Lee JH, Park HK, Kim KS.

Biochem Biophys Res Commun. 2016 May 6;473(3):752-7. doi: 10.1016/j.bbrc.2015.09.081. Epub 2015 Sep 25. Review.


The effects of dynamic compression on the development of cartilage grafts engineered using bone marrow and infrapatellar fat pad derived stem cells.

Luo L, Thorpe SD, Buckley CT, Kelly DJ.

Biomed Mater. 2015 Sep 21;10(5):055011. doi: 10.1088/1748-6041/10/5/055011.


Cell Mechanosensitivity to Extremely Low-Magnitude Signals Is Enabled by a LINCed Nucleus.

Uzer G, Thompson WR, Sen B, Xie Z, Yen SS, Miller S, Bas G, Styner M, Rubin CT, Judex S, Burridge K, Rubin J.

Stem Cells. 2015 Jun;33(6):2063-76. doi: 10.1002/stem.2004.


Mechanical regulation of mesenchymal stem cell differentiation.

Steward AJ, Kelly DJ.

J Anat. 2015 Dec;227(6):717-31. doi: 10.1111/joa.12243. Epub 2014 Nov 9. Review.


Mechanical stimulation of mesenchymal stem cell proliferation and differentiation promotes osteogenesis while preventing dietary-induced obesity.

Luu YK, Capilla E, Rosen CJ, Gilsanz V, Pessin JE, Judex S, Rubin CT.

J Bone Miner Res. 2009 Jan;24(1):50-61. doi: 10.1359/jbmr.080817.


Modulating the actin cytoskeleton affects mechanically induced signal transduction and differentiation in mesenchymal stem cells.

Müller P, Langenbach A, Kaminski A, Rychly J.

PLoS One. 2013 Jul 29;8(7):e71283. doi: 10.1371/journal.pone.0071283. Print 2013.

Supplemental Content

Support Center