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Items: 1 to 20 of 354

1.

Prdm16 determines the thermogenic program of subcutaneous white adipose tissue in mice.

Seale P, Conroe HM, Estall J, Kajimura S, Frontini A, Ishibashi J, Cohen P, Cinti S, Spiegelman BM.

J Clin Invest. 2011 Jan;121(1):96-105. doi: 10.1172/JCI44271. Epub 2010 Dec 1.

2.

Transcriptional control of brown fat determination by PRDM16.

Seale P, Kajimura S, Yang W, Chin S, Rohas LM, Uldry M, Tavernier G, Langin D, Spiegelman BM.

Cell Metab. 2007 Jul;6(1):38-54.

3.

Beige differentiation of adipose depots in mice lacking prolactin receptor protects against high-fat-diet-induced obesity.

Auffret J, Viengchareun S, Carré N, Denis RG, Magnan C, Marie PY, Muscat A, Fève B, Lombès M, Binart N.

FASEB J. 2012 Sep;26(9):3728-37. doi: 10.1096/fj.12-204958. Epub 2012 May 25.

4.

Role of PRDM16 in the activation of brown fat programming. Relevance to the development of obesity.

Becerril S, Gómez-Ambrosi J, Martín M, Moncada R, Sesma P, Burrell MA, Frühbeck G.

Histol Histopathol. 2013 Nov;28(11):1411-25. doi: 10.14670/HH-28.1411. Epub 2013 Jun 17. Review.

PMID:
23771475
5.

Transcription factor Hlx controls a systematic switch from white to brown fat through Prdm16-mediated co-activation.

Huang L, Pan D, Chen Q, Zhu LJ, Ou J, Wabitsch M, Wang YX.

Nat Commun. 2017 Jul 12;8(1):68. doi: 10.1038/s41467-017-00098-2.

6.

Rorα deficiency and decreased adiposity are associated with induction of thermogenic gene expression in subcutaneous white adipose and brown adipose tissue.

Lau P, Tuong ZK, Wang SC, Fitzsimmons RL, Goode JM, Thomas GP, Cowin GJ, Pearen MA, Mardon K, Stow JL, Muscat GE.

Am J Physiol Endocrinol Metab. 2015 Jan 15;308(2):E159-71. doi: 10.1152/ajpendo.00056.2014. Epub 2014 Nov 25.

7.
8.

GQ-16, a TZD-Derived Partial PPARγ Agonist, Induces the Expression of Thermogenesis-Related Genes in Brown Fat and Visceral White Fat and Decreases Visceral Adiposity in Obese and Hyperglycemic Mice.

Coelho MS, de Lima CL, Royer C, Silva JB, Oliveira FC, Christ CG, Pereira SA, Bao SN, Lima MC, Pitta MG, Pitta IR, Neves FA, Amato AA.

PLoS One. 2016 May 3;11(5):e0154310. doi: 10.1371/journal.pone.0154310. eCollection 2016.

9.

Erythropoietin (EPO) ameliorates obesity and glucose homeostasis by promoting thermogenesis and endocrine function of classical brown adipose tissue (BAT) in diet-induced obese mice.

Kodo K, Sugimoto S, Nakajima H, Mori J, Itoh I, Fukuhara S, Shigehara K, Nishikawa T, Kosaka K, Hosoi H.

PLoS One. 2017 Mar 13;12(3):e0173661. doi: 10.1371/journal.pone.0173661. eCollection 2017.

10.

Adipose subtype-selective recruitment of TLE3 or Prdm16 by PPARγ specifies lipid storage versus thermogenic gene programs.

Villanueva CJ, Vergnes L, Wang J, Drew BG, Hong C, Tu Y, Hu Y, Peng X, Xu F, Saez E, Wroblewski K, Hevener AL, Reue K, Fong LG, Young SG, Tontonoz P.

Cell Metab. 2013 Mar 5;17(3):423-35. doi: 10.1016/j.cmet.2013.01.016.

11.

Ablation of PRDM16 and beige adipose causes metabolic dysfunction and a subcutaneous to visceral fat switch.

Cohen P, Levy JD, Zhang Y, Frontini A, Kolodin DP, Svensson KJ, Lo JC, Zeng X, Ye L, Khandekar MJ, Wu J, Gunawardana SC, Banks AS, Camporez JP, Jurczak MJ, Kajimura S, Piston DW, Mathis D, Cinti S, Shulman GI, Seale P, Spiegelman BM.

Cell. 2014 Jan 16;156(1-2):304-16. doi: 10.1016/j.cell.2013.12.021.

12.

Brown adipose tissue: the molecular mechanism of its formation.

Wolf G.

Nutr Rev. 2009 Mar;67(3):167-71. doi: 10.1111/j.1753-4887.2009.00184.x. Review.

PMID:
19239631
13.

Eicosapentaenoic acid regulates brown adipose tissue metabolism in high-fat-fed mice and in clonal brown adipocytes.

Pahlavani M, Razafimanjato F, Ramalingam L, Kalupahana NS, Moussa H, Scoggin S, Moustaid-Moussa N.

J Nutr Biochem. 2017 Jan;39:101-109. doi: 10.1016/j.jnutbio.2016.08.012. Epub 2016 Sep 22.

14.

Peroxisome proliferator-activated receptor α (PPARα) induces PPARγ coactivator 1α (PGC-1α) gene expression and contributes to thermogenic activation of brown fat: involvement of PRDM16.

Hondares E, Rosell M, Díaz-Delfín J, Olmos Y, Monsalve M, Iglesias R, Villarroya F, Giralt M.

J Biol Chem. 2011 Dec 16;286(50):43112-22. doi: 10.1074/jbc.M111.252775. Epub 2011 Oct 27.

15.

Cardiac natriuretic peptides act via p38 MAPK to induce the brown fat thermogenic program in mouse and human adipocytes.

Bordicchia M, Liu D, Amri EZ, Ailhaud G, Dessì-Fulgheri P, Zhang C, Takahashi N, Sarzani R, Collins S.

J Clin Invest. 2012 Mar;122(3):1022-36. doi: 10.1172/JCI59701. Epub 2012 Feb 6. Erratum in: J Clin Invest. 2012 Apr 2;122(4):1584.

16.

PPARγ agonists induce a white-to-brown fat conversion through stabilization of PRDM16 protein.

Ohno H, Shinoda K, Spiegelman BM, Kajimura S.

Cell Metab. 2012 Mar 7;15(3):395-404. doi: 10.1016/j.cmet.2012.01.019.

17.

Dietary luteolin activates browning and thermogenesis in mice through an AMPK/PGC1α pathway-mediated mechanism.

Zhang X, Zhang QX, Wang X, Zhang L, Qu W, Bao B, Liu CA, Liu J.

Int J Obes (Lond). 2016 Dec;40(12):1841-1849. doi: 10.1038/ijo.2016.108. Epub 2016 Jul 5.

PMID:
27377953
18.

White to brown fat phenotypic switch induced by genetic and environmental activation of a hypothalamic-adipocyte axis.

Cao L, Choi EY, Liu X, Martin A, Wang C, Xu X, During MJ.

Cell Metab. 2011 Sep 7;14(3):324-38. doi: 10.1016/j.cmet.2011.06.020.

19.

Thermoneutrality decreases thermogenic program and promotes adiposity in high-fat diet-fed mice.

Cui X, Nguyen NL, Zarebidaki E, Cao Q, Li F, Zha L, Bartness T, Shi H, Xue B.

Physiol Rep. 2016 May;4(10). pii: e12799. doi: 10.14814/phy2.12799.

20.

Direct evidence of brown adipocytes in different fat depots in children.

Rockstroh D, Landgraf K, Wagner IV, Gesing J, Tauscher R, Lakowa N, Kiess W, Bühligen U, Wojan M, Till H, Blüher M, Körner A.

PLoS One. 2015 Feb 23;10(2):e0117841. doi: 10.1371/journal.pone.0117841. eCollection 2015.

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