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Effects of a high dose, aglycone-rich soy extract on prostate-specific antigen and serum isoflavone concentrations in men with localized prostate cancer.

deVere White RW, Tsodikov A, Stapp EC, Soares SE, Fujii H, Hackman RM.

Nutr Cancer. 2010;62(8):1036-43. doi: 10.1080/01635581.2010.492085.


Soy isoflavones in the treatment of prostate cancer.

Hussain M, Banerjee M, Sarkar FH, Djuric Z, Pollak MN, Doerge D, Fontana J, Chinni S, Davis J, Forman J, Wood DP, Kucuk O.

Nutr Cancer. 2003;47(2):111-7.


Clinical characteristics and pharmacokinetics of purified soy isoflavones: multiple-dose administration to men with prostate neoplasia.

Fischer L, Mahoney C, Jeffcoat AR, Koch MA, Thomas BE, Valentine JL, Stinchcombe T, Boan J, Crowell JA, Zeisel SH.

Nutr Cancer. 2004;48(2):160-70.


Lycopene and soy isoflavones in the treatment of prostate cancer.

Vaishampayan U, Hussain M, Banerjee M, Seren S, Sarkar FH, Fontana J, Forman JD, Cher ML, Powell I, Pontes JE, Kucuk O.

Nutr Cancer. 2007;59(1):1-7.


Effects of a genistein-rich extract on PSA levels in men with a history of prostate cancer.

deVere White RW, Hackman RM, Soares SE, Beckett LA, Li Y, Sun B.

Urology. 2004 Feb;63(2):259-63.


A preliminary study of the safety, feasibility and cognitive efficacy of soy isoflavone supplements in older men and women.

Gleason CE, Carlsson CM, Barnet JH, Meade SA, Setchell KD, Atwood CS, Johnson SC, Ries ML, Asthana S.

Age Ageing. 2009 Jan;38(1):86-93. doi: 10.1093/ageing/afn227. Epub 2008 Dec 2.


Prostatic soy isoflavone concentrations exceed serum levels after dietary supplementation.

Gardner CD, Oelrich B, Liu JP, Feldman D, Franke AA, Brooks JD.

Prostate. 2009 May 15;69(7):719-26. doi: 10.1002/pros.20922.


Phase II trial of isoflavone in prostate-specific antigen recurrent prostate cancer after previous local therapy.

Pendleton JM, Tan WW, Anai S, Chang M, Hou W, Shiverick KT, Rosser CJ.

BMC Cancer. 2008 May 11;8:132. doi: 10.1186/1471-2407-8-132.


Is daidzein non-metabolizer a high risk for prostate cancer? A case-controlled study of serum soybean isoflavone concentration.

Akaza H, Miyanaga N, Takashima N, Naito S, Hirao Y, Tsukamoto T, Mori M.

Jpn J Clin Oncol. 2002 Aug;32(8):296-300.


Short-term soy isoflavone intervention in patients with localized prostate cancer: a randomized, double-blind, placebo-controlled trial.

Hamilton-Reeves JM, Banerjee S, Banerjee SK, Holzbeierlein JM, Thrasher JB, Kambhampati S, Keighley J, Van Veldhuizen P.

PLoS One. 2013 Jul 12;8(7):e68331. doi: 10.1371/journal.pone.0068331. Print 2013.


Effect of a soy isoflavone supplement on lung function and clinical outcomes in patients with poorly controlled asthma: a randomized clinical trial.

Smith LJ, Kalhan R, Wise RA, Sugar EA, Lima JJ, Irvin CG, Dozor AJ, Holbrook JT; American Lung Association Asthma Clinical Research Centers.

JAMA. 2015 May 26;313(20):2033-43. doi: 10.1001/jama.2015.5024.


Acute benefits of the microbial-derived isoflavone metabolite equol on arterial stiffness in men prospectively recruited according to equol producer phenotype: a double-blind randomized controlled trial.

Hazim S, Curtis PJ, Schär MY, Ostertag LM, Kay CD, Minihane AM, Cassidy A.

Am J Clin Nutr. 2016 Mar;103(3):694-702. doi: 10.3945/ajcn.115.125690. Epub 2016 Feb 3.


Long-term dietary habits affect soy isoflavone metabolism and accumulation in prostatic fluid in caucasian men.

Hedlund TE, Maroni PD, Ferucci PG, Dayton R, Barnes S, Jones K, Moore R, Ogden LG, Wähälä K, Sackett HM, Gray KJ.

J Nutr. 2005 Jun;135(6):1400-6.


A Phase II randomized, placebo-controlled clinical trial of purified isoflavones in modulating steroid hormones in men diagnosed with localized prostate cancer.

Kumar NB, Krischer JP, Allen K, Riccardi D, Besterman-Dahan K, Salup R, Kang L, Xu P, Pow-Sang J.

Nutr Cancer. 2007;59(2):163-8.


Relationship of serum levels and dietary intake of isoflavone, and the novel bacterium Slackia sp. strain NATTS with the risk of prostate cancer: a case-control study among Japanese men.

Nagata Y, Sugiyama Y, Fukuta F, Takayanagi A, Masumori N, Tsukamoto T, Akasaka H, Ohnishi H, Saitoh S, Miura T, Moriyama K, Tsuji H, Akaza H, Mori M.

Int Urol Nephrol. 2016 Sep;48(9):1453-60. doi: 10.1007/s11255-016-1335-7. Epub 2016 Jun 4.


Prostate cancer chemoprevention study: an investigative randomized control study using purified isoflavones in men with rising prostate-specific antigen.

Miyanaga N, Akaza H, Hinotsu S, Fujioka T, Naito S, Namiki M, Takahashi S, Hirao Y, Horie S, Tsukamoto T, Mori M, Tsuji H.

Cancer Sci. 2012 Jan;103(1):125-30. doi: 10.1111/j.1349-7006.2011.02120.x. Epub 2011 Nov 9.


Efficacy and safety of short-term genistein intervention in patients with localized prostate cancer prior to radical prostatectomy: a randomized, placebo-controlled, double-blind Phase 2 clinical trial.

Lazarevic B, Boezelijn G, Diep LM, Kvernrod K, Ogren O, Ramberg H, Moen A, Wessel N, Berg RE, Egge-Jacobsen W, Hammarstrom C, Svindland A, Kucuk O, Saatcioglu F, Taskèn KA, Karlsen SJ.

Nutr Cancer. 2011;63(6):889-98. doi: 10.1080/01635581.2011.582221. Epub 2011 Jun 29.


Large inter-individual variation in isoflavone plasma concentration limits use of isoflavone intake data for risk assessment.

van der Velpen V, Hollman PC, van Nielen M, Schouten EG, Mensink M, Van't Veer P, Geelen A.

Eur J Clin Nutr. 2014 Oct;68(10):1141-7. doi: 10.1038/ejcn.2014.108. Epub 2014 Jun 18.


Distribution of isoflavones in samples of serum, liver and mammary glands of rats or pigs fed dietary isoflavones.

Gilani GS, Farmer C, Dyck M, Robertson P, Dahiya J, Sepehr E, Fan L, Nicolidakis H, Curran I, Cooke GM.

Ann Nutr Metab. 2011;58(3):171-80. doi: 10.1159/000328771. Epub 2011 Jun 8.


Impact of equol-producing capacity and soy-isoflavone profiles of supplements on bone calcium retention in postmenopausal women: a randomized crossover trial.

Pawlowski JW, Martin BR, McCabe GP, McCabe L, Jackson GS, Peacock M, Barnes S, Weaver CM.

Am J Clin Nutr. 2015 Sep;102(3):695-703. doi: 10.3945/ajcn.114.093906. Epub 2015 Aug 5.

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