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Association of nuclear localization of a long interspersed nuclear element-1 protein in breast tumors with poor prognostic outcomes.

Harris CR, Normart R, Yang Q, Stevenson E, Haffty BG, Ganesan S, Cordon-Cardo C, Levine AJ, Tang LH.

Genes Cancer. 2010 Feb;1(2):115-24. doi: 10.1177/1947601909360812.


Prognostic value of LINE-1 retrotransposon expression and its subcellular localization in breast cancer.

Chen L, Dahlstrom JE, Chandra A, Board P, Rangasamy D.

Breast Cancer Res Treat. 2012 Nov;136(1):129-42. doi: 10.1007/s10549-012-2246-7. Epub 2012 Sep 29.


Characterization of L1 ORF1p self-interaction and cellular localization using a mammalian two-hybrid system.

Sokolowski M, deHaro D, Christian CM, Kines KJ, Belancio VP.

PLoS One. 2013 Dec 4;8(12):e82021. doi: 10.1371/journal.pone.0082021. eCollection 2013.


Detection of the LINE-1 retrotransposon RNA-binding protein ORF1p in different anatomical regions of the human brain.

Sur D, Kustwar RK, Budania S, Mahadevan A, Hancks DC, Yadav V, Shankar SK, Mandal PK.

Mob DNA. 2017 Nov 22;8:17. doi: 10.1186/s13100-017-0101-4. eCollection 2017.


Long interspersed nuclear element-1 expression and retrotransposition in prostate cancer cells.

Briggs EM, Ha S, Mita P, Brittingham G, Sciamanna I, Spadafora C, Logan SK.

Mob DNA. 2018 Jan 3;9:1. doi: 10.1186/s13100-017-0106-z. eCollection 2018.


Guardian of the Human Genome: Host Defense Mechanisms against LINE-1 Retrotransposition.

Ariumi Y.

Front Chem. 2016 Jun 28;4:28. doi: 10.3389/fchem.2016.00028. eCollection 2016. Review.


Paired mutations abolish and restore the balanced annealing and melting activities of ORF1p that are required for LINE-1 retrotransposition.

Evans JD, Peddigari S, Chaurasiya KR, Williams MC, Martin SL.

Nucleic Acids Res. 2011 Jul;39(13):5611-21. doi: 10.1093/nar/gkr171. Epub 2011 Mar 26.


Spatial assembly and RNA binding stoichiometry of a LINE-1 protein essential for retrotransposition.

Basame S, Wai-lun Li P, Howard G, Branciforte D, Keller D, Martin SL.

J Mol Biol. 2006 Mar 24;357(2):351-7. Epub 2006 Jan 6.


A single amino acid substitution in ORF1 dramatically decreases L1 retrotransposition and provides insight into nucleic acid chaperone activity.

Martin SL, Bushman D, Wang F, Li PW, Walker A, Cummiskey J, Branciforte D, Williams MC.

Nucleic Acids Res. 2008 Oct;36(18):5845-54. doi: 10.1093/nar/gkn554. Epub 2008 Sep 12.


MicroRNA miR-128 represses LINE-1 (L1) retrotransposition by down-regulating the nuclear import factor TNPO1.

Idica A, Sevrioukov EA, Zisoulis DG, Hamdorf M, Daugaard I, Kadandale P, Pedersen IM.

J Biol Chem. 2017 Dec 15;292(50):20494-20508. doi: 10.1074/jbc.M117.807677. Epub 2017 Oct 3.


Reprogramming somatic cells into iPS cells activates LINE-1 retroelement mobility.

Wissing S, Muñoz-Lopez M, Macia A, Yang Z, Montano M, Collins W, Garcia-Perez JL, Moran JV, Greene WC.

Hum Mol Genet. 2012 Jan 1;21(1):208-18. doi: 10.1093/hmg/ddr455. Epub 2011 Oct 11.


Inhibition of LINE-1 expression in the heart decreases ischemic damage by activation of Akt/PKB signaling.

Lucchinetti E, Feng J, Silva Rd, Tolstonog GV, Schaub MC, Schumann GG, Zaugg M.

Physiol Genomics. 2006 Apr 13;25(2):314-24. Epub 2006 Jan 17.


Nucleic acid chaperone properties of ORF1p from the non-LTR retrotransposon, LINE-1.

Martin SL.

RNA Biol. 2010 Nov-Dec;7(6):706-11. Epub 2010 Nov 1. Review.


Identification and solution structure of a highly conserved C-terminal domain within ORF1p required for retrotransposition of long interspersed nuclear element-1.

Januszyk K, Li PW, Villareal V, Branciforte D, Wu H, Xie Y, Feigon J, Loo JA, Martin SL, Clubb RT.

J Biol Chem. 2007 Aug 24;282(34):24893-904. Epub 2007 Jun 14.


LINE-1 ORF1 protein enhances Alu SINE retrotransposition.

Wallace N, Wagstaff BJ, Deininger PL, Roy-Engel AM.

Gene. 2008 Aug 1;419(1-2):1-6. doi: 10.1016/j.gene.2008.04.007. Epub 2008 Apr 24.


Trimeric structure for an essential protein in L1 retrotransposition.

Martin SL, Branciforte D, Keller D, Bain DL.

Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):13815-20. Epub 2003 Nov 13.


Ribonucleoprotein particle formation is necessary but not sufficient for LINE-1 retrotransposition.

Kulpa DA, Moran JV.

Hum Mol Genet. 2005 Nov 1;14(21):3237-48. Epub 2005 Sep 23.


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