Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 98

1.

The regulation of factor IXa by supersulfated low molecular weight heparin.

Misenheimer TM, Sheehan JP.

Biochemistry. 2010 Nov 23;49(46):9997-10005. doi: 10.1021/bi100906q. Epub 2010 Oct 27.

2.
4.

Heparin inhibits the intrinsic tenase complex by interacting with an exosite on factor IXa.

Sheehan JP, Kobbervig CE, Kirkpatrick HM.

Biochemistry. 2003 Sep 30;42(38):11316-25.

PMID:
14503882
6.

Low molecular weight heparin inhibits plasma thrombin generation via direct targeting of factor IXa: contribution of the serpin-independent mechanism.

Buyue Y, Misenheimer TM, Sheehan JP.

J Thromb Haemost. 2012 Oct;10(10):2086-98. doi: 10.1111/j.1538-7836.2012.04892.x.

7.

Selective disruption of heparin and antithrombin-mediated regulation of human factor IX.

Westmark PR, Tanratana P, Sheehan JP.

J Thromb Haemost. 2015 Jun;13(6):1053-63. doi: 10.1111/jth.12960. Epub 2015 May 10.

8.

Phosphorothioate oligonucleotides inhibit the intrinsic tenase complex by an allosteric mechanism.

Sheehan JP, Phan TM.

Biochemistry. 2001 Apr 24;40(16):4980-9.

PMID:
11305914
9.

Fucosylated chondroitin sulfate inhibits plasma thrombin generation via targeting of the factor IXa heparin-binding exosite.

Buyue Y, Sheehan JP.

Blood. 2009 Oct 1;114(14):3092-100. doi: 10.1182/blood-2009-02-203661. Epub 2009 May 4.

10.
11.

The heparin-binding exosite of factor IXa is a critical regulator of plasma thrombin generation and venous thrombosis.

Buyue Y, Whinna HC, Sheehan JP.

Blood. 2008 Oct 15;112(8):3234-41. doi: 10.1182/blood-2008-01-136820. Epub 2008 Jul 22.

12.

Conformational activation of antithrombin by heparin involves an altered exosite interaction with protease.

Izaguirre G, Aguila S, Qi L, Swanson R, Roth R, Rezaie AR, Gettins PG, Olson ST.

J Biol Chem. 2014 Dec 5;289(49):34049-64. doi: 10.1074/jbc.M114.611707. Epub 2014 Oct 20.

13.

Factor IXa:factor VIIIa interaction. helix 330-338 of factor ixa interacts with residues 558-565 and spatially adjacent regions of the a2 subunit of factor VIIIa.

Bajaj SP, Schmidt AE, Mathur A, Padmanabhan K, Zhong D, Mastri M, Fay PJ.

J Biol Chem. 2001 May 11;276(19):16302-9. Epub 2001 Feb 14.

14.

Surface loop 199-204 in blood coagulation factor IX is a cofactor-dependent site involved in macromolecular substrate interaction.

Kolkman JA, Christophe OD, Lenting PJ, Mertens K.

J Biol Chem. 1999 Oct 8;274(41):29087-93.

15.

Contribution of the NH2-terminal EGF-domain of factor IXa to the specificity of intrinsic tenase.

Qureshi SH, Yang L, Rezaie AR.

Thromb Haemost. 2012 Dec;108(6):1154-64. doi: 10.1160/TH12-06-0436. Epub 2012 Sep 26.

17.

Structural integrity of the gamma-carboxyglutamic acid domain of human blood coagulation factor IXa Is required for its binding to cofactor VIIIa.

Larson PJ, Stanfield-Oakley SA, VanDusen WJ, Kasper CK, Smith KJ, Monroe DM, High KA.

J Biol Chem. 1996 Feb 16;271(7):3869-76.

18.

Na+ site in blood coagulation factor IXa: effect on catalysis and factor VIIIa binding.

Schmidt AE, Stewart JE, Mathur A, Krishnaswamy S, Bajaj SP.

J Mol Biol. 2005 Jul 1;350(1):78-91.

PMID:
15913649
19.

The factor VIIIa C2 domain (residues 2228-2240) interacts with the factor IXa Gla domain in the factor Xase complex.

Soeda T, Nogami K, Nishiya K, Takeyama M, Ogiwara K, Sakata Y, Yoshioka A, Shima M.

J Biol Chem. 2009 Feb 6;284(6):3379-88. doi: 10.1074/jbc.M804955200. Epub 2008 Dec 1.

Supplemental Content

Support Center