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Items: 1 to 20 of 122

1.

Targeted mutations in the Na,K-ATPase α 2 isoform confer ouabain resistance and result in abnormal behavior in mice.

Schaefer TL, Lingrel JB, Moseley AE, Vorhees CV, Williams MT.

Synapse. 2011 Jun;65(6):520-31. doi: 10.1002/syn.20870. Epub 2010 Nov 17.

2.

ACTH-induced hypertension is dependent on the ouabain-binding site of the alpha2-Na+-K+-ATPase subunit.

Lorenz JN, Loreaux EL, Dostanic-Larson I, Lasko V, Schnetzer JR, Paul RJ, Lingrel JB.

Am J Physiol Heart Circ Physiol. 2008 Jul;295(1):H273-80. doi: 10.1152/ajpheart.00183.2008. Epub 2008 May 16.

3.

Deficiency in Na,K-ATPase alpha isoform genes alters spatial learning, motor activity, and anxiety in mice.

Moseley AE, Williams MT, Schaefer TL, Bohanan CS, Neumann JC, Behbehani MM, Vorhees CV, Lingrel JB.

J Neurosci. 2007 Jan 17;27(3):616-26.

4.

The ouabain-binding site of the α2 isoform of Na,K-ATPase plays a role in blood pressure regulation during pregnancy.

Oshiro N, Dostanic-Larson I, Neumann JC, Lingrel JB.

Am J Hypertens. 2010 Dec;23(12):1279-85. doi: 10.1038/ajh.2010.195. Epub 2010 Sep 9.

5.

The highly conserved cardiac glycoside binding site of Na,K-ATPase plays a role in blood pressure regulation.

Dostanic-Larson I, Van Huysse JW, Lorenz JN, Lingrel JB.

Proc Natl Acad Sci U S A. 2005 Nov 1;102(44):15845-50. Epub 2005 Oct 21.

6.

Hypertension from chronic central sodium chloride in mice is mediated by the ouabain-binding site on the Na,K-ATPase α₂-isoform.

Van Huysse JW, Dostanic I, Lingrel JB, Hou X, Wu H.

Am J Physiol Heart Circ Physiol. 2011 Nov;301(5):H2147-53. doi: 10.1152/ajpheart.01216.2010. Epub 2011 Aug 19.

7.

Na(+)/K)+)-ATPase α2-isoform preferentially modulates Ca2(+) transients and sarcoplasmic reticulum Ca2(+) release in cardiac myocytes.

Despa S, Lingrel JB, Bers DM.

Cardiovasc Res. 2012 Sep 1;95(4):480-6. doi: 10.1093/cvr/cvs213. Epub 2012 Jun 27.

9.

Mice expressing ouabain-sensitive α1-Na,K-ATPase have increased susceptibility to pressure overload-induced cardiac hypertrophy.

Wansapura AN, Lasko VM, Lingrel JB, Lorenz JN.

Am J Physiol Heart Circ Physiol. 2011 Jan;300(1):H347-55. doi: 10.1152/ajpheart.00625.2010. Epub 2010 Oct 15.

10.

Physiological role of the alpha1- and alpha2-isoforms of the Na+-K+-ATPase and biological significance of their cardiac glycoside binding site.

Dostanic-Larson I, Lorenz JN, Van Huysse JW, Neumann JC, Moseley AE, Lingrel JB.

Am J Physiol Regul Integr Comp Physiol. 2006 Mar;290(3):R524-8. Review.

12.

DOCA-salt hypertension does not require the ouabain-sensitive binding site of the α2 Na,K-ATPase.

Lorenz JN, Oshiro N, Loreaux EL, Lingrel JB.

Am J Hypertens. 2012 Apr;25(4):421-9. doi: 10.1038/ajh.2011.255. Epub 2012 Jan 19.

13.

Ouabain-Sensitive alpha1 Na,K-ATPase enhances natriuretic response to saline load.

Loreaux EL, Kaul B, Lorenz JN, Lingrel JB.

J Am Soc Nephrol. 2008 Oct;19(10):1947-54. doi: 10.1681/ASN.2008020174. Epub 2008 Jul 30.

14.

Na,K-ATPase alpha 2 inhibition alters calcium responses in optic nerve astrocytes.

Hartford AK, Messer ML, Moseley AE, Lingrel JB, Delamere NA.

Glia. 2004 Feb;45(3):229-37.

PMID:
14730696
15.

Ouabain inhibits tubuloglomerular feedback in mutant mice with ouabain-sensitive alpha1 Na,K-ATPase.

Lorenz JN, Dostanic-Larson I, Shull GE, Lingrel JB.

J Am Soc Nephrol. 2006 Sep;17(9):2457-63. Epub 2006 Jul 26.

16.

Ouabain sensitivity and expression of Na/K-ATPase alpha- and beta-subunit isoform genes during bovine early development.

Betts DH, MacPhee DJ, Kidder GM, Watson AJ.

Mol Reprod Dev. 1997 Feb;46(2):114-26.

PMID:
9021743
17.

Marinobufagenin enhances cardiac contractility in mice with ouabain-sensitive alpha1 Na+-K+-ATPase.

Wansapura AN, Lasko V, Xie Z, Fedorova OV, Bagrov AY, Lingrel JB, Lorenz JN.

Am J Physiol Heart Circ Physiol. 2009 Jun;296(6):H1833-9. doi: 10.1152/ajpheart.00285.2009. Epub 2009 Apr 17.

18.

The cardiac glycoside binding site on the Na,K-ATPase alpha2 isoform plays a role in the dynamic regulation of active transport in skeletal muscle.

Radzyukevich TL, Lingrel JB, Heiny JA.

Proc Natl Acad Sci U S A. 2009 Feb 24;106(8):2565-70. doi: 10.1073/pnas.0804150106. Epub 2009 Feb 5.

19.

Functional characterization of a testes-specific alpha-subunit isoform of the sodium/potassium adenosinetriphosphatase.

Blanco G, Melton RJ, Sánchez G, Mercer RW.

Biochemistry. 1999 Oct 12;38(41):13661-9.

PMID:
10521273
20.

The alpha2 isoform of Na,K-ATPase mediates ouabain-induced cardiac inotropy in mice.

Dostanic I, Lorenz JN, Schultz Jel J, Grupp IL, Neumann JC, Wani MA, Lingrel JB.

J Biol Chem. 2003 Dec 26;278(52):53026-34. Epub 2003 Oct 14.

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