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Items: 1 to 20 of 197

1.

Measurement of the cellular deacetylase activity of SIRT1 on p53 via LanthaScreen® technology.

Robers MB, Loh C, Carlson CB, Yang H, Frey EA, Hermanson SB, Bi K.

Mol Biosyst. 2011 Jan;7(1):59-66. doi: 10.1039/c0mb00026d. Epub 2010 Oct 8.

PMID:
20931131
2.

HIPK2 modulates p53 activity towards pro-apoptotic transcription.

Puca R, Nardinocchi L, Sacchi A, Rechavi G, Givol D, D'Orazi G.

Mol Cancer. 2009 Oct 14;8:85. doi: 10.1186/1476-4598-8-85.

3.

Inhibition of SIRT1 catalytic activity increases p53 acetylation but does not alter cell survival following DNA damage.

Solomon JM, Pasupuleti R, Xu L, McDonagh T, Curtis R, DiStefano PS, Huber LJ.

Mol Cell Biol. 2006 Jan;26(1):28-38.

4.

SIRT1 deacetylation and repression of p300 involves lysine residues 1020/1024 within the cell cycle regulatory domain 1.

Bouras T, Fu M, Sauve AA, Wang F, Quong AA, Perkins ND, Hay RT, Gu W, Pestell RG.

J Biol Chem. 2005 Mar 18;280(11):10264-76. Epub 2005 Jan 4.

5.

p53 deacetylation by SIRT1 decreases during protein kinase CKII downregulation-mediated cellular senescence.

Jang SY, Kim SY, Bae YS.

FEBS Lett. 2011 Nov 4;585(21):3360-6. doi: 10.1016/j.febslet.2011.09.027. Epub 2011 Sep 29.

7.

Active regulator of SIRT1 cooperates with SIRT1 and facilitates suppression of p53 activity.

Kim EJ, Kho JH, Kang MR, Um SJ.

Mol Cell. 2007 Oct 26;28(2):277-90. Erratum in: Mol Cell. 2007 Nov 9;28(3):513.

8.

Multiple histone deacetylases and the CREB-binding protein regulate pre-mRNA 3'-end processing.

Shimazu T, Horinouchi S, Yoshida M.

J Biol Chem. 2007 Feb 16;282(7):4470-8. Epub 2006 Dec 17.

9.

Nox1 is involved in p53 deacetylation and suppression of its transcriptional activity and apoptosis.

Puca R, Nardinocchi L, Starace G, Rechavi G, Sacchi A, Givol D, D'Orazi G.

Free Radic Biol Med. 2010 May 15;48(10):1338-46. doi: 10.1016/j.freeradbiomed.2010.02.015. Epub 2010 Feb 18.

PMID:
20171273
10.

Induction of PIG3 and NOXA through acetylation of p53 at 320 and 373 lysine residues as a mechanism for apoptotic cell death by histone deacetylase inhibitors.

Terui T, Murakami K, Takimoto R, Takahashi M, Takada K, Murakami T, Minami S, Matsunaga T, Takayama T, Kato J, Niitsu Y.

Cancer Res. 2003 Dec 15;63(24):8948-54.

11.

Deacetylation of the retinoblastoma tumour suppressor protein by SIRT1.

Wong S, Weber JD.

Biochem J. 2007 Nov 1;407(3):451-60.

12.

Methyltransferase Set7/9 regulates p53 activity by interacting with Sirtuin 1 (SIRT1).

Liu X, Wang D, Zhao Y, Tu B, Zheng Z, Wang L, Wang H, Gu W, Roeder RG, Zhu WG.

Proc Natl Acad Sci U S A. 2011 Feb 1;108(5):1925-30. doi: 10.1073/pnas.1019619108. Epub 2011 Jan 18.

13.

Acetylation of Sirt2 by p300 attenuates its deacetylase activity.

Han Y, Jin YH, Kim YJ, Kang BY, Choi HJ, Kim DW, Yeo CY, Lee KY.

Biochem Biophys Res Commun. 2008 Oct 31;375(4):576-80. doi: 10.1016/j.bbrc.2008.08.042. Epub 2008 Aug 21.

PMID:
18722353
14.

cAMP signalling inhibits p53 acetylation and apoptosis via HDAC and SIRT deacetylases.

Kloster MM, Naderi EH, Haaland I, Gjertsen BT, Blomhoff HK, Naderi S.

Int J Oncol. 2013 May;42(5):1815-21. doi: 10.3892/ijo.2013.1853. Epub 2013 Mar 8.

PMID:
23483263
15.

TR-FRET cellular assays for interrogating posttranslational modifications of histone H3.

Machleidt T, Robers MB, Hermanson SB, Dudek JM, Bi K.

J Biomol Screen. 2011 Dec;16(10):1236-46. doi: 10.1177/1087057111422943. Epub 2011 Oct 4.

PMID:
21972037
16.

Histone deacetylases specifically down-regulate p53-dependent gene activation.

Juan LJ, Shia WJ, Chen MH, Yang WM, Seto E, Lin YS, Wu CW.

J Biol Chem. 2000 Jul 7;275(27):20436-43.

17.

TR-FRET biochemical assays for detecting posttranslational modifications of p53.

Dudek JM, Horton RA.

J Biomol Screen. 2010 Jun;15(5):569-75. doi: 10.1177/1087057110365898. Epub 2010 Apr 16.

PMID:
20400726
18.

Opposing effects of hMOF and SIRT1 on H4K16 acetylation and the sensitivity to the topoisomerase II inhibitor etoposide.

Hajji N, Wallenborg K, Vlachos P, F├╝llgrabe J, Hermanson O, Joseph B.

Oncogene. 2010 Apr 15;29(15):2192-204. doi: 10.1038/onc.2009.505. Epub 2010 Feb 1.

PMID:
20118981
19.

Necdin regulates p53 acetylation via Sirtuin1 to modulate DNA damage response in cortical neurons.

Hasegawa K, Yoshikawa K.

J Neurosci. 2008 Aug 27;28(35):8772-84. doi: 10.1523/JNEUROSCI.3052-08.2008.

20.

Histone deacetylase inhibitor-mediated radiosensitization of human cancer cells: class differences and the potential influence of p53.

Kim IA, Shin JH, Kim IH, Kim JH, Kim JS, Wu HG, Chie EK, Ha SW, Park CI, Kao GD.

Clin Cancer Res. 2006 Feb 1;12(3 Pt 1):940-9.

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