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Items: 1 to 20 of 140

1.

Differential effects of resveratrol and SRT1720 on lifespan of adult Caenorhabditis elegans.

Zarse K, Schmeisser S, Birringer M, Falk E, Schmoll D, Ristow M.

Horm Metab Res. 2010 Nov;42(12):837-9. doi: 10.1055/s-0030-1265225. Epub 2010 Oct 5.

PMID:
20925017
2.

Lipid-lowering fibrates extend C. elegans lifespan in a NHR-49/PPARalpha-dependent manner.

Brandstädt S, Schmeisser K, Zarse K, Ristow M.

Aging (Albany NY). 2013 Apr;5(4):270-5.

3.

Lonidamine extends lifespan of adult Caenorhabditis elegans by increasing the formation of mitochondrial reactive oxygen species.

Schmeisser S, Zarse K, Ristow M.

Horm Metab Res. 2011 Sep;43(10):687-92. doi: 10.1055/s-0031-1286308. Epub 2011 Sep 19.

PMID:
21932172
4.

The phytochemical glaucarubinone promotes mitochondrial metabolism, reduces body fat, and extends lifespan of Caenorhabditis elegans.

Zarse K, Bossecker A, Müller-Kuhrt L, Siems K, Hernandez MA, Berendsohn WG, Birringer M, Ristow M.

Horm Metab Res. 2011 Apr;43(4):241-3. doi: 10.1055/s-0030-1270524. Epub 2011 Jan 24.

PMID:
21264793
5.

L-Theanine extends lifespan of adult Caenorhabditis elegans.

Zarse K, Jabin S, Ristow M.

Eur J Nutr. 2012 Sep;51(6):765-8. doi: 10.1007/s00394-012-0341-5. Epub 2012 Mar 16.

6.

Effects of resveratrol on lifespan in Drosophila melanogaster and Caenorhabditis elegans.

Bass TM, Weinkove D, Houthoofd K, Gems D, Partridge L.

Mech Ageing Dev. 2007 Oct;128(10):546-52. Epub 2007 Aug 14.

PMID:
17875315
7.

Procyanidins from apples (Malus pumila Mill.) extend the lifespan of Caenorhabditis elegans.

Sunagawa T, Shimizu T, Kanda T, Tagashira M, Sami M, Shirasawa T.

Planta Med. 2011 Jan;77(2):122-7. doi: 10.1055/s-0030-1250204. Epub 2010 Aug 17.

PMID:
20717869
8.

The resveratrol derivatives trans-3,5-dimethoxy-4-fluoro-4'-hydroxystilbene and trans-2,4',5-trihydroxystilbene decrease oxidative stress and prolong lifespan in Caenorhabditis elegans.

Fischer N, Büchter C, Koch K, Albert S, Csuk R, Wätjen W.

J Pharm Pharmacol. 2017 Jan;69(1):73-81. doi: 10.1111/jphp.12657. Epub 2016 Nov 23.

PMID:
27882602
9.

Brief Communication: SIR-2.1-dependent lifespan extension of Caenorhabditis elegans by oxyresveratrol and resveratrol.

Lee J, Kwon G, Park J, Kim JK, Lim YH.

Exp Biol Med (Maywood). 2016 Oct;241(16):1757-63. doi: 10.1177/1535370216650054. Epub 2016 May 10.

10.

Autophagy mediates pharmacological lifespan extension by spermidine and resveratrol.

Morselli E, Galluzzi L, Kepp O, Criollo A, Maiuri MC, Tavernarakis N, Madeo F, Kroemer G.

Aging (Albany NY). 2009 Dec 23;1(12):961-70. Review.

11.

SRT1720, SRT2183, SRT1460, and resveratrol are not direct activators of SIRT1.

Pacholec M, Bleasdale JE, Chrunyk B, Cunningham D, Flynn D, Garofalo RS, Griffith D, Griffor M, Loulakis P, Pabst B, Qiu X, Stockman B, Thanabal V, Varghese A, Ward J, Withka J, Ahn K.

J Biol Chem. 2010 Mar 12;285(11):8340-51. doi: 10.1074/jbc.M109.088682. Epub 2010 Jan 8.

12.

Sirtuin activators mimic caloric restriction and delay ageing in metazoans.

Wood JG, Rogina B, Lavu S, Howitz K, Helfand SL, Tatar M, Sinclair D.

Nature. 2004 Aug 5;430(7000):686-9. Epub 2004 Jul 14. Erratum in: Nature. 2004 Sep 2;431(7004):107.

PMID:
15254550
13.

Influence of resveratrol on oxidative stress resistance and life span in Caenorhabditis elegans.

Chen W, Rezaizadehnajafi L, Wink M.

J Pharm Pharmacol. 2013 May;65(5):682-8. doi: 10.1111/jphp.12023. Epub 2013 Jan 31.

PMID:
23600385
14.

Caloric restriction and resveratrol promote longevity through the Sirtuin-1-dependent induction of autophagy.

Morselli E, Maiuri MC, Markaki M, Megalou E, Pasparaki A, Palikaras K, Criollo A, Galluzzi L, Malik SA, Vitale I, Michaud M, Madeo F, Tavernarakis N, Kroemer G.

Cell Death Dis. 2010;1:e10. doi: 10.1038/cddis.2009.8.

15.

Significant longevity-extending effects of Alpinia zerumbet leaf extract on the life span of Caenorhabditis elegans.

Upadhyay A, Chompoo J, Taira N, Fukuta M, Tawata S.

Biosci Biotechnol Biochem. 2013;77(2):217-23. Epub 2013 Feb 7.

16.

Reverse chemomodulatory effects of the SIRT1 activators resveratrol and SRT1720 in Ewing's sarcoma cells: resveratrol suppresses and SRT1720 enhances etoposide- and vincristine-induced anticancer activity.

Sonnemann J, Kahl M, Siranjeevi PM, Blumrich A, Blümel L, Becker S, Wittig S, Winkler R, Krämer OH, Beck JF.

J Cancer Res Clin Oncol. 2016 Jan;142(1):17-26. doi: 10.1007/s00432-015-1994-2. Epub 2015 Jun 9.

PMID:
26055805
17.

Lower Doses of Fructose Extend Lifespan in Caenorhabditis elegans.

Zheng J, Gao C, Wang M, Tran P, Mai N, Finley JW, Heymsfield SB, Greenway FL, Li Z, Heber D, Burton JH, Johnson WD, Laine RA.

J Diet Suppl. 2017 May 4;14(3):264-277. Epub 2016 Sep 28.

PMID:
27680107
18.

Screening lifespan-extending drugs in Caenorhabditis elegans via label propagation on drug-protein networks.

Liu H, Guo M, Xue T, Guan J, Luo L, Zhuang Z.

BMC Syst Biol. 2016 Dec 23;10(Suppl 4):131. doi: 10.1186/s12918-016-0362-4.

19.

Pharmacology of delayed aging and extended lifespan of Caenorhabditis elegans.

Collins JJ, Evason K, Kornfeld K.

Exp Gerontol. 2006 Oct;41(10):1032-9. Epub 2006 Jul 26. Review.

PMID:
16872777
20.

The SIRT1 activator SRT1720 extends lifespan and improves health of mice fed a standard diet.

Mitchell SJ, Martin-Montalvo A, Mercken EM, Palacios HH, Ward TM, Abulwerdi G, Minor RK, Vlasuk GP, Ellis JL, Sinclair DA, Dawson J, Allison DB, Zhang Y, Becker KG, Bernier M, de Cabo R.

Cell Rep. 2014 Mar 13;6(5):836-43. doi: 10.1016/j.celrep.2014.01.031. Epub 2014 Feb 27.

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