Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 79

1.

LRRK2 is involved in the IFN-gamma response and host response to pathogens.

Gardet A, Benita Y, Li C, Sands BE, Ballester I, Stevens C, Korzenik JR, Rioux JD, Daly MJ, Xavier RJ, Podolsky DK.

J Immunol. 2010 Nov 1;185(9):5577-85. doi: 10.4049/jimmunol.1000548. Epub 2010 Oct 4.

2.

Interferon-γ induces leucine-rich repeat kinase LRRK2 via extracellular signal-regulated kinase ERK5 in macrophages.

Kuss M, Adamopoulou E, Kahle PJ.

J Neurochem. 2014 Jun;129(6):980-7. doi: 10.1111/jnc.12668. Epub 2014 Feb 24.

3.

Parkinson's disease-linked LRRK2 is expressed in circulating and tissue immune cells and upregulated following recognition of microbial structures.

Hakimi M, Selvanantham T, Swinton E, Padmore RF, Tong Y, Kabbach G, Venderova K, Girardin SE, Bulman DE, Scherzer CR, LaVoie MJ, Gris D, Park DS, Angel JB, Shen J, Philpott DJ, Schlossmacher MG.

J Neural Transm (Vienna). 2011 May;118(5):795-808. doi: 10.1007/s00702-011-0653-2. Epub 2011 May 7.

4.

LRRK2 guides the actin cytoskeleton at growth cones together with ARHGEF7 and Tropomyosin 4.

Häbig K, Gellhaar S, Heim B, Djuric V, Giesert F, Wurst W, Walter C, Hentrich T, Riess O, Bonin M.

Biochim Biophys Acta. 2013 Dec;1832(12):2352-67. doi: 10.1016/j.bbadis.2013.09.009. Epub 2013 Sep 24.

5.

Cross-talk between RORγt+ innate lymphoid cells and intestinal macrophages induces mucosal IL-22 production in Crohn's disease.

Mizuno S, Mikami Y, Kamada N, Handa T, Hayashi A, Sato T, Matsuoka K, Matano M, Ohta Y, Sugita A, Koganei K, Sahara R, Takazoe M, Hisamatsu T, Kanai T.

Inflamm Bowel Dis. 2014 Aug;20(8):1426-34. doi: 10.1097/MIB.0000000000000105.

PMID:
24991784
6.

Overexpression of ATP-activated P2X7 receptors in the intestinal mucosa is implicated in the pathogenesis of Crohn's disease.

Neves AR, Castelo-Branco MT, Figliuolo VR, Bernardazzi C, Buongusto F, Yoshimoto A, Nanini HF, Coutinho CM, Carneiro AJ, Coutinho-Silva R, de Souza HS.

Inflamm Bowel Dis. 2014 Mar;20(3):444-57. doi: 10.1097/01.MIB.0000441201.10454.06.

PMID:
24412990
7.

Leucine-rich repeat kinase 2-sensitive Na+/Ca2+ exchanger activity in dendritic cells.

Yan J, Almilaji A, Schmid E, Elvira B, Shimshek DR, van der Putten H, Wagner CA, Shumilina E, Lang F.

FASEB J. 2015 May;29(5):1701-10. doi: 10.1096/fj.14-264028. Epub 2015 Jan 21.

8.

Cholera toxin subunit B inhibits IL-12 and IFN-{gamma} production and signaling in experimental colitis and Crohn's disease.

Coccia EM, Remoli ME, Di Giacinto C, Del Zotto B, Giacomini E, Monteleone G, Boirivant M.

Gut. 2005 Nov;54(11):1558-64. Epub 2005 Aug 16.

9.

Mucosal NOD2 expression and NF-kappaB activation in pediatric Crohn's disease.

Stronati L, Negroni A, Merola P, Pannone V, Borrelli O, Cirulli M, Annese V, Cucchiara S.

Inflamm Bowel Dis. 2008 Mar;14(3):295-302.

PMID:
18092345
10.

LRRK2 and human disease: a complicated question or a question of complexes?

Lewis PA, Manzoni C.

Sci Signal. 2012 Jan 17;5(207):pe2. doi: 10.1126/scisignal.2002680.

PMID:
22253261
11.

NADH oxidase-dependent CD39 expression by CD8(+) T cells modulates interferon gamma responses via generation of adenosine.

Bai A, Moss A, Rothweiler S, Longhi MS, Wu Y, Junger WG, Robson SC.

Nat Commun. 2015 Nov 9;6:8819. doi: 10.1038/ncomms9819.

13.

Activation of NOD2-mediated intestinal pathway in a pediatric population with Crohn's disease.

Negroni A, Stronati L, Pierdomenico M, Tirindelli D, Di Nardo G, Mancini V, Maiella G, Cucchiara S.

Inflamm Bowel Dis. 2009 Aug;15(8):1145-54. doi: 10.1002/ibd.20907.

PMID:
19266573
14.

The increased expression of IL-23 in inflammatory bowel disease promotes intraepithelial and lamina propria lymphocyte inflammatory responses and cytotoxicity.

Liu Z, Yadav PK, Xu X, Su J, Chen C, Tang M, Lin H, Yu J, Qian J, Yang PC, Wang X.

J Leukoc Biol. 2011 Apr;89(4):597-606. doi: 10.1189/jlb.0810456. Epub 2011 Jan 7.

PMID:
21227898
15.

Scaffolding adaptor protein Gab1 is required for TLR3/4- and RIG-I-mediated production of proinflammatory cytokines and type I IFN in macrophages.

Zheng Y, An H, Yao M, Hou J, Yu Y, Feng G, Cao X.

J Immunol. 2010 Jun 1;184(11):6447-56. doi: 10.4049/jimmunol.0901750. Epub 2010 Apr 30.

16.

Leucine-rich repeat kinase 2 is a regulator of B cell function, affecting homeostasis, BCR signaling, IgA production, and TI antigen responses.

Kubo M, Nagashima R, Ohta E, Maekawa T, Isobe Y, Kurihara M, Eshima K, Iwabuchi K, Sasaoka T, Azuma S, Melrose HL, Farrer MJ, Obata F.

J Neuroimmunol. 2016 Mar 15;292:1-8. doi: 10.1016/j.jneuroim.2016.01.005. Epub 2016 Jan 8.

PMID:
26943952
17.

TGR5 signalling inhibits the production of pro-inflammatory cytokines by in vitro differentiated inflammatory and intestinal macrophages in Crohn's disease.

Yoneno K, Hisamatsu T, Shimamura K, Kamada N, Ichikawa R, Kitazume MT, Mori M, Uo M, Namikawa Y, Matsuoka K, Sato T, Koganei K, Sugita A, Kanai T, Hibi T.

Immunology. 2013 May;139(1):19-29. doi: 10.1111/imm.12045.

18.

The role of the novel Th17 cytokine IL-26 in intestinal inflammation.

Dambacher J, Beigel F, Zitzmann K, De Toni EN, Göke B, Diepolder HM, Auernhammer CJ, Brand S.

Gut. 2009 Sep;58(9):1207-17. doi: 10.1136/gut.2007.130112. Epub 2008 May 15.

PMID:
18483078
19.
20.

Involvement of interleukin 18 in Crohn's disease: evidence from in vitro analysis of human gut inflammatory cells and from experimental colitis models.

Maerten P, Shen C, Colpaert S, Liu Z, Bullens DA, van Assche G, Penninckx F, Geboes K, Vanham G, Rutgeerts P, Ceuppens JL.

Clin Exp Immunol. 2004 Feb;135(2):310-7.

Supplemental Content

Support Center