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Dendritic cells reveal a broad range of MHC class I epitopes for HIV-1 in persons with suppressed viral load on antiretroviral therapy.

Huang XL, Fan Z, Borowski L, Mailliard RB, Rolland M, Mullins JI, Day RD, Rinaldo CR.

PLoS One. 2010 Sep 23;5(9):e12936. doi: 10.1371/journal.pone.0012936.


Effective Cytotoxic T Lymphocyte Targeting of Persistent HIV-1 during Antiretroviral Therapy Requires Priming of Naive CD8+ T Cells.

Smith KN, Mailliard RB, Piazza PA, Fischer W, Korber BT, Fecek RJ, Ratner D, Gupta P, Mullins JI, Rinaldo CR.

MBio. 2016 May 31;7(3). pii: e00473-16. doi: 10.1128/mBio.00473-16. Erratum in: MBio. 2016;7(4). pii: e01012-16. doi: 10.1128/mBio.01012-16.


Plasmacytoid dendritic cell and functional HIV Gag p55-specific T cells before treatment interruption can inform set-point plasma HIV viral load after treatment interruption in chronically suppressed HIV-1(+) patients.

Papasavvas E, Foulkes A, Yin X, Joseph J, Ross B, Azzoni L, Kostman JR, Mounzer K, Shull J, Montaner LJ.

Immunology. 2015 Jul;145(3):380-90. doi: 10.1111/imm.12452. Epub 2015 May 19.


Preclinical evaluation of HIV-1 therapeutic ex vivo dendritic cell vaccines expressing consensus Gag antigens and conserved Gag epitopes.

Niu L, Termini JM, Kanagavelu SK, Gupta S, Rolland MM, Kulkarni V, Pavlakis GN, Felber BK, Mullins JI, Fischl MA, Stone GW.

Vaccine. 2011 Mar 3;29(11):2110-9. doi: 10.1016/j.vaccine.2010.12.131. Epub 2011 Jan 15.


Multiple T-cell responses to human immunodeficiency virus type 1 are enhanced by dendritic cells.

Huang XL, Fan Z, Borowski L, Rinaldo CR.

Clin Vaccine Immunol. 2009 Oct;16(10):1504-16. doi: 10.1128/CVI.00104-09. Epub 2009 Aug 19. Erratum in: Clin Vaccine Immunol. 2009 Nov;16(11):1707.


Primary human immunodeficiency virus type 1-specific CD8+ T-cell responses induced by myeloid dendritic cells.

Colleton BA, Huang XL, Melhem NM, Fan Z, Borowski L, Rappocciolo G, Rinaldo CR.

J Virol. 2009 Jun;83(12):6288-99. doi: 10.1128/JVI.02611-08. Epub 2009 Apr 8.


Anti-human immunodeficiency virus type 1 (HIV-1) CD8(+) T-lymphocyte reactivity during combination antiretroviral therapy in HIV-1-infected patients with advanced immunodeficiency.

Rinaldo CR Jr, Huang XL, Fan Z, Margolick JB, Borowski L, Hoji A, Kalinyak C, McMahon DK, Riddler SA, Hildebrand WH, Day RB, Mellors JW.

J Virol. 2000 May;74(9):4127-38.


An IL-15 dependent CD8 T cell response to selected HIV epitopes is related to viral control in early-treated HIV-infected subjects.

D'Offizi G, Gioia C, Corpolongo A, Martini F, Paganelli R, Volpi I, Sacchi A, Tozzi V, Narciso P, Poccia F.

Int J Immunopathol Pharmacol. 2007 Jul-Sep;20(3):473-85.


Frequency of class I HLA-restricted anti-HIV CD8+ T cells in individuals receiving highly active antiretroviral therapy (HAART).

Gray CM, Lawrence J, Schapiro JM, Altman JD, Winters MA, Crompton M, Loi M, Kundu SK, Davis MM, Merigan TC.

J Immunol. 1999 Feb 1;162(3):1780-8.


Downregulation of major histocompatibility class I on human dendritic cells by HIV Nef impairs antigen presentation to HIV-specific CD8+ T lymphocytes.

Andrieu M, Chassin D, Desoutter JF, Bouchaert I, Baillet M, Hanau D, Guillet JG, Hosmalin A.

AIDS Res Hum Retroviruses. 2001 Sep 20;17(14):1365-70.


Dendritic cells restore CD8+ T cell reactivity to autologous HIV-1.

Smith KN, Mailliard RB, Larsen BB, Wong K, Gupta P, Mullins JI, Rinaldo CR.

J Virol. 2014 Sep 1;88(17):9976-90. doi: 10.1128/JVI.01275-14. Epub 2014 Jun 18.


Virological outcome after structured interruption of antiretroviral therapy for human immunodeficiency virus infection is associated with the functional profile of virus-specific CD8+ T cells.

Daucher M, Price DA, Brenchley JM, Lamoreaux L, Metcalf JA, Rehm C, Nies-Kraske E, Urban E, Yoder C, Rock D, Gumkowski J, Betts MR, Dybul MR, Douek DC.

J Virol. 2008 Apr;82(8):4102-14. doi: 10.1128/JVI.02212-07. Epub 2008 Jan 30.


Levels of antigen processing machinery components in dendritic cells generated for vaccination of HIV-1+ subjects.

Connolly N, Riddler S, Stanson J, Gooding W, Rinaldo CR, Ferrone S, Whiteside TL.

AIDS. 2007 Aug 20;21(13):1683-92.


Dendritic cells generated in the presence of granulocyte-macrophage colony-stimulating factor and IFN-alpha are potent inducers of HIV-specific CD8 T cells.

Carbonneil C, Aouba A, Burgard M, Cardinaud S, Rouzioux C, Langlade-Demoyen P, Weiss L.

AIDS. 2003 Aug 15;17(12):1731-40.


Role of human immunodeficiency virus (HIV)-specific T-cell immunity in control of dual HIV-1 and HIV-2 infection.

Zheng NN, McElrath MJ, Sow PS, Hawes SE, Diallo-Agne H, Stern JE, Li F, Mesher AL, Robinson AD, Gottlieb GS, Huang Y, Kiviat NB.

J Virol. 2007 Sep;81(17):9061-71. Epub 2007 Jun 20.


Maturation of dendritic cells for enhanced activation of anti-HIV-1 CD8(+) T cell immunity.

Huang XL, Fan Z, Borowski L, Rinaldo CR.

J Leukoc Biol. 2008 Jun;83(6):1530-40. doi: 10.1189/jlb.1107795. Epub 2008 Mar 25.


Functional discrepancies in HIV-specific CD8+ T-lymphocyte populations are related to plasma virus load.

Oxenius A, Sewell AK, Dawson SJ, G√ľnthard HF, Fischer M, Gillespie GM, Rowland-Jones SL, Fagard C, Hirschel B, Phillips RE, Price DA; Swiss HIV Cohort Study.

J Clin Immunol. 2002 Nov;22(6):363-74.


HIV-Specific CD8+ T Cell-Mediated Viral Suppression Correlates With the Expression of CD57.

Jensen SS, Tingstedt JL, Larsen TK, Brandt L, Gerstoft J, Kronborg G, Pedersen C, Fomsgaard A, Karlsson I.

J Acquir Immune Defic Syndr. 2016 Jan 1;71(1):8-16. doi: 10.1097/QAI.0000000000000837.


Early and prolonged antiretroviral therapy is associated with an HIV-1-specific T-cell profile comparable to that of long-term non-progressors.

Cellerai C, Harari A, Stauss H, Yerly S, Geretti AM, Carroll A, Yee T, Ainsworth J, Williams I, Sweeney J, Freedman A, Johnson M, Pantaleo G, Kinloch-de Loes S.

PLoS One. 2011 Apr 5;6(4):e18164. doi: 10.1371/journal.pone.0018164.

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