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Items: 1 to 20 of 121

1.

Functional and inflammatory alterations in the lung following exposure of rats to nitrogen mustard.

Sunil VR, Patel KJ, Shen J, Reimer D, Gow AJ, Laskin JD, Laskin DL.

Toxicol Appl Pharmacol. 2011 Jan 1;250(1):10-8. doi: 10.1016/j.taap.2010.09.016. Epub 2010 Sep 29.

2.

Pentoxifylline attenuates nitrogen mustard-induced acute lung injury, oxidative stress and inflammation.

Sunil VR, Vayas KN, Cervelli JA, Malaviya R, Hall L, Massa CB, Gow AJ, Laskin JD, Laskin DL.

Exp Mol Pathol. 2014 Aug;97(1):89-98. doi: 10.1016/j.yexmp.2014.05.009. Epub 2014 Jun 2.

3.

Role of reactive nitrogen species generated via inducible nitric oxide synthase in vesicant-induced lung injury, inflammation and altered lung functioning.

Sunil VR, Shen J, Patel-Vayas K, Gow AJ, Laskin JD, Laskin DL.

Toxicol Appl Pharmacol. 2012 May 15;261(1):22-30. doi: 10.1016/j.taap.2012.03.004. Epub 2012 Mar 14.

4.

Attenuation of acute nitrogen mustard-induced lung injury, inflammation and fibrogenesis by a nitric oxide synthase inhibitor.

Malaviya R, Venosa A, Hall L, Gow AJ, Sinko PJ, Laskin JD, Laskin DL.

Toxicol Appl Pharmacol. 2012 Dec 15;265(3):279-91. doi: 10.1016/j.taap.2012.08.027. Epub 2012 Sep 6.

5.

Role of TNFR1 in lung injury and altered lung function induced by the model sulfur mustard vesicant, 2-chloroethyl ethyl sulfide.

Sunil VR, Patel-Vayas K, Shen J, Gow AJ, Laskin JD, Laskin DL.

Toxicol Appl Pharmacol. 2011 Feb 1;250(3):245-55. doi: 10.1016/j.taap.2010.10.027. Epub 2010 Nov 9.

6.

Inflammatory effects of inhaled sulfur mustard in rat lung.

Malaviya R, Sunil VR, Cervelli J, Anderson DR, Holmes WW, Conti ML, Gordon RE, Laskin JD, Laskin DL.

Toxicol Appl Pharmacol. 2010 Oct 15;248(2):89-99. doi: 10.1016/j.taap.2010.07.018. Epub 2010 Jul 24.

7.

Attenuation of Nitrogen Mustard-Induced Pulmonary Injury and Fibrosis by Anti-Tumor Necrosis Factor-α Antibody.

Malaviya R, Sunil VR, Venosa A, Verissimo VL, Cervelli JA, Vayas KN, Hall L, Laskin JD, Laskin DL.

Toxicol Sci. 2015 Nov;148(1):71-88. doi: 10.1093/toxsci/kfv161. Epub 2015 Aug 4.

8.

Protective role of spleen-derived macrophages in lung inflammation, injury, and fibrosis induced by nitrogen mustard.

Venosa A, Malaviya R, Gow AJ, Hall L, Laskin JD, Laskin DL.

Am J Physiol Lung Cell Mol Physiol. 2015 Dec 15;309(12):L1487-98. doi: 10.1152/ajplung.00276.2015. Epub 2015 Oct 16.

9.

Characterization of Distinct Macrophage Subpopulations during Nitrogen Mustard-Induced Lung Injury and Fibrosis.

Venosa A, Malaviya R, Choi H, Gow AJ, Laskin JD, Laskin DL.

Am J Respir Cell Mol Biol. 2016 Mar;54(3):436-46. doi: 10.1165/rcmb.2015-0120OC.

10.

Inflammatory mechanisms of pulmonary injury induced by mustards.

Malaviya R, Sunil VR, Venosa A, Vayas KN, Heck DE, Laskin JD, Laskin DL.

Toxicol Lett. 2016 Feb 26;244:2-7. doi: 10.1016/j.toxlet.2015.10.011. Epub 2015 Oct 23. Review.

11.

Mustard vesicant-induced lung injury: Advances in therapy.

Weinberger B, Malaviya R, Sunil VR, Venosa A, Heck DE, Laskin JD, Laskin DL.

Toxicol Appl Pharmacol. 2016 Aug 15;305:1-11. doi: 10.1016/j.taap.2016.05.014. Epub 2016 May 19. Review.

PMID:
27212445
12.

Nitrogen Mustard-Induced Corneal Injury Involves DNA Damage and Pathways Related to Inflammation, Epithelial-Stromal Separation, and Neovascularization.

Goswami DG, Tewari-Singh N, Dhar D, Kumar D, Agarwal C, Ammar DA, Kant R, Enzenauer RW, Petrash JM, Agarwal R.

Cornea. 2016 Feb;35(2):257-66. doi: 10.1097/ICO.0000000000000685.

13.

Tissue injury following inhalation of fine particulate matter and hydrogen peroxide is associated with altered production of inflammatory mediators and antioxidants by alveolar macrophages.

Morio LA, Hooper KA, Brittingham J, Li TH, Gordon RE, Turpin BJ, Laskin DL.

Toxicol Appl Pharmacol. 2001 Dec 15;177(3):188-99.

PMID:
11749118
14.

Nitrogen mustard exposure of murine skin induces DNA damage, oxidative stress and activation of MAPK/Akt-AP1 pathway leading to induction of inflammatory and proteolytic mediators.

Kumar D, Tewari-Singh N, Agarwal C, Jain AK, Inturi S, Kant R, White CW, Agarwal R.

Toxicol Lett. 2015 Jun 15;235(3):161-71. doi: 10.1016/j.toxlet.2015.04.006. Epub 2015 Apr 16.

15.

Prolonged injury and altered lung function after ozone inhalation in mice with chronic lung inflammation.

Groves AM, Gow AJ, Massa CB, Laskin JD, Laskin DL.

Am J Respir Cell Mol Biol. 2012 Dec;47(6):776-83. doi: 10.1165/rcmb.2011-0433OC. Epub 2012 Aug 9.

16.

Ozone-induced injury and oxidative stress in bronchiolar epithelium are associated with altered pulmonary mechanics.

Sunil VR, Vayas KN, Massa CB, Gow AJ, Laskin JD, Laskin DL.

Toxicol Sci. 2013 Jun;133(2):309-19. doi: 10.1093/toxsci/kft071. Epub 2013 Mar 14.

17.

Myeloperoxidase deficiency attenuates nitrogen mustard-induced skin injuries.

Jain AK, Tewari-Singh N, Inturi S, Orlicky DJ, White CW, Agarwal R.

Toxicology. 2014 Jun 5;320:25-33. doi: 10.1016/j.tox.2014.02.013. Epub 2014 Mar 12.

18.

Deficiency in inducible nitric oxide synthase protects mice from ozone-induced lung inflammation and tissue injury.

Fakhrzadeh L, Laskin JD, Laskin DL.

Am J Respir Cell Mol Biol. 2002 Apr;26(4):413-9.

PMID:
11919077
19.
20.

Inhaled nitric oxide primes lung macrophages to produce reactive oxygen and nitrogen intermediates.

Weinberger B, Fakhrzadeh L, Heck DE, Laskin JD, Gardner CR, Laskin DL.

Am J Respir Crit Care Med. 1998 Sep;158(3):931-8.

PMID:
9731028

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