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Items: 1 to 20 of 111

1.

InsP3R-associated cGMP kinase substrate determines inositol 1,4,5-trisphosphate receptor susceptibility to phosphoregulation by cyclic nucleotide-dependent kinases.

Masuda W, Betzenhauser MJ, Yule DI.

J Biol Chem. 2010 Nov 26;285(48):37927-38. doi: 10.1074/jbc.M110.168989. Epub 2010 Sep 27.

2.

Molecular determinants of the interaction between the inositol 1,4,5-trisphosphate receptor-associated cGMP kinase substrate (IRAG) and cGMP kinase Ibeta.

Ammendola A, Geiselhöringer A, Hofmann F, Schlossmann J.

J Biol Chem. 2001 Jun 29;276(26):24153-9. Epub 2001 Apr 17.

3.
5.

Functional osteoclast attachment requires inositol-1,4,5-trisphosphate receptor-associated cGMP-dependent kinase substrate.

Yaroslavskiy BB, Turkova I, Wang Y, Robinson LJ, Blair HC.

Lab Invest. 2010 Oct;90(10):1533-42. doi: 10.1038/labinvest.2010.120. Epub 2010 Jun 21.

6.

Protein kinase A increases type-2 inositol 1,4,5-trisphosphate receptor activity by phosphorylation of serine 937.

Betzenhauser MJ, Fike JL, Wagner LE 2nd, Yule DI.

J Biol Chem. 2009 Sep 11;284(37):25116-25. doi: 10.1074/jbc.M109.010132. Epub 2009 Jul 16.

7.

Regulation of single inositol 1,4,5-trisphosphate receptor channel activity by protein kinase A phosphorylation.

Wagner LE 2nd, Joseph SK, Yule DI.

J Physiol. 2008 Aug 1;586(15):3577-96. doi: 10.1113/jphysiol.2008.152314. Epub 2008 Jun 5.

8.

IRAG determines nitric oxide- and atrial natriuretic peptide-mediated smooth muscle relaxation.

Desch M, Sigl K, Hieke B, Salb K, Kees F, Bernhard D, Jochim A, Spiessberger B, Höcherl K, Feil R, Feil S, Lukowski R, Wegener JW, Hofmann F, Schlossmann J.

Cardiovasc Res. 2010 Jun 1;86(3):496-505. doi: 10.1093/cvr/cvq008. Epub 2010 Jan 15.

PMID:
20080989
9.

IRAG and novel PKG targeting in the cardiovascular system.

Schlossmann J, Desch M.

Am J Physiol Heart Circ Physiol. 2011 Sep;301(3):H672-82. doi: 10.1152/ajpheart.00198.2011. Epub 2011 Jun 10. Review.

10.

InsP3R-associated cGMP kinase substrate (IRAG) is essential for nitric oxide-induced inhibition of calcium signaling in human colonic smooth muscle.

Fritsch RM, Saur D, Kurjak M, Oesterle D, Schlossmann J, Geiselhöringer A, Hofmann F, Allescher HD.

J Biol Chem. 2004 Mar 26;279(13):12551-9. Epub 2004 Jan 18.

11.

Selective phosphorylation of the IP3R-I in vivo by cGMP-dependent protein kinase in smooth muscle.

Murthy KS, Zhou H.

Am J Physiol Gastrointest Liver Physiol. 2003 Feb;284(2):G221-30.

12.

IRAG is essential for relaxation of receptor-triggered smooth muscle contraction by cGMP kinase.

Geiselhöringer A, Werner M, Sigl K, Smital P, Wörner R, Acheo L, Stieber J, Weinmeister P, Feil R, Feil S, Wegener J, Hofmann F, Schlossmann J.

EMBO J. 2004 Oct 27;23(21):4222-31. Epub 2004 Oct 14.

13.
14.

cGMP-dependent protein kinase anchoring by IRAG regulates its nuclear translocation and transcriptional activity.

Casteel DE, Zhang T, Zhuang S, Pilz RB.

Cell Signal. 2008 Jul;20(7):1392-9. doi: 10.1016/j.cellsig.2008.03.009. Epub 2008 Mar 26.

15.

Regulation of intracellular calcium by a signalling complex of IRAG, IP3 receptor and cGMP kinase Ibeta.

Schlossmann J, Ammendola A, Ashman K, Zong X, Huber A, Neubauer G, Wang GX, Allescher HD, Korth M, Wilm M, Hofmann F, Ruth P.

Nature. 2000 Mar 9;404(6774):197-201.

PMID:
10724174
16.

Distribution of IRAG and cGKI-isoforms in murine tissues.

Geiselhöringer A, Gaisa M, Hofmann F, Schlossmann J.

FEBS Lett. 2004 Sep 24;575(1-3):19-22.

17.

cGMP/Protein Kinase G Signaling Suppresses Inositol 1,4,5-Trisphosphate Receptor Phosphorylation and Promotes Endoplasmic Reticulum Stress in Photoreceptors of Cyclic Nucleotide-gated Channel-deficient Mice.

Ma H, Butler MR, Thapa A, Belcher J, Yang F, Baehr W, Biel M, Michalakis S, Ding XQ.

J Biol Chem. 2015 Aug 21;290(34):20880-92. doi: 10.1074/jbc.M115.641159. Epub 2015 Jun 29.

18.
19.

A role for phosphorylation of inositol 1,4,5-trisphosphate receptors in defining calcium signals induced by Peptide agonists in pancreatic acinar cells.

Straub SV, Giovannucci DR, Bruce JI, Yule DI.

J Biol Chem. 2002 Aug 30;277(35):31949-56. Epub 2002 Jun 13.

20.

IRAG mediates NO/cGMP-dependent inhibition of platelet aggregation and thrombus formation.

Antl M, von Brühl ML, Eiglsperger C, Werner M, Konrad I, Kocher T, Wilm M, Hofmann F, Massberg S, Schlossmann J.

Blood. 2007 Jan 15;109(2):552-9. Epub 2006 Sep 21.

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