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Items: 1 to 20 of 201

1.

Neural stem cells reduce hippocampal tau and reelin accumulation in aged Ts65Dn Down syndrome mice.

Kern DS, Maclean KN, Jiang H, Synder EY, Sladek JR Jr, Bjugstad KB.

Cell Transplant. 2011;20(3):371-9. doi: 10.3727/096368910X528085. Epub 2010 Sep 27.

PMID:
20875225
2.

Reduced Reelin expression accelerates amyloid-beta plaque formation and tau pathology in transgenic Alzheimer's disease mice.

Kocherhans S, Madhusudan A, Doehner J, Breu KS, Nitsch RM, Fritschy JM, Knuesel I.

J Neurosci. 2010 Jul 7;30(27):9228-40. doi: 10.1523/JNEUROSCI.0418-10.2010.

3.

Age-related accumulation of Reelin in amyloid-like deposits.

Knuesel I, Nyffeler M, Mormède C, Muhia M, Meyer U, Pietropaolo S, Yee BK, Pryce CR, LaFerla FM, Marighetto A, Feldon J.

Neurobiol Aging. 2009 May;30(5):697-716. Epub 2007 Sep 27.

PMID:
17904250
4.

Modulating cognitive deficits and tau accumulation in a mouse model of aging Down syndrome through neonatal implantation of neural progenitor cells.

Rachubinski AL, Maclean KN, Evans JR, Bjugstad KB.

Exp Gerontol. 2012 Sep;47(9):723-33. doi: 10.1016/j.exger.2012.06.013. Epub 2012 Jul 7.

PMID:
22776132
5.

Reelin-immunoreactivity in the hippocampal formation of 9-month-old wildtype mouse: effects of APP/PS1 genotype and ovariectomy.

Miettinen R, Riedel A, Kalesnykas G, Kettunen HP, Puoliväli J, Soininen H, Arendt T.

J Chem Neuroanat. 2005 Oct;30(2-3):105-18.

PMID:
16081247
6.

Beta-amyloid controls altered Reelin expression and processing in Alzheimer's disease.

Botella-López A, Cuchillo-Ibáñez I, Cotrufo T, Mok SS, Li QX, Barquero MS, Dierssen M, Soriano E, Sáez-Valero J.

Neurobiol Dis. 2010 Mar;37(3):682-91. doi: 10.1016/j.nbd.2009.12.006. Epub 2009 Dec 16.

PMID:
20025970
7.

Co-localization of Reelin and proteolytic AbetaPP fragments in hippocampal plaques in aged wild-type mice.

Doehner J, Madhusudan A, Konietzko U, Fritschy JM, Knuesel I.

J Alzheimers Dis. 2010;19(4):1339-57. doi: 10.3233/JAD-2010-1333.

PMID:
20061602
8.

Impaired Src signaling and post-synaptic actin polymerization in Alzheimer's disease mice hippocampus--linking NMDA receptors and the reelin pathway.

Mota SI, Ferreira IL, Valero J, Ferreiro E, Carvalho AL, Oliveira CR, Rego AC.

Exp Neurol. 2014 Nov;261:698-709. doi: 10.1016/j.expneurol.2014.07.023. Epub 2014 Aug 13.

PMID:
25128699
9.

Dysregulation of tau phosphorylation is a hypothesized point of convergence in the pathogenesis of alzheimer's disease, frontotemporal dementia and schizophrenia with therapeutic implications.

Deutsch SI, Rosse RB, Lakshman RM.

Prog Neuropsychopharmacol Biol Psychiatry. 2006 Dec 30;30(8):1369-80. Epub 2006 Jun 21. Review.

PMID:
16793187
10.

Reelin depletion in the entorhinal cortex of human amyloid precursor protein transgenic mice and humans with Alzheimer's disease.

Chin J, Massaro CM, Palop JJ, Thwin MT, Yu GQ, Bien-Ly N, Bender A, Mucke L.

J Neurosci. 2007 Mar 14;27(11):2727-33.

11.

Accumulation of reelin-positive plaques is accompanied by a decline in basal forebrain projection neurons during normal aging.

Madhusudan A, Sidler C, Knuesel I.

Eur J Neurosci. 2009 Sep;30(6):1064-76. doi: 10.1111/j.1460-9568.2009.06884.x. Epub 2009 Sep 4.

PMID:
19735296
12.

Reelin in plaques of beta-amyloid precursor protein and presenilin-1 double-transgenic mice.

Wirths O, Multhaup G, Czech C, Blanchard V, Tremp G, Pradier L, Beyreuther K, Bayer TA.

Neurosci Lett. 2001 Dec 28;316(3):145-8.

PMID:
11744223
13.

App gene dosage modulates endosomal abnormalities of Alzheimer's disease in a segmental trisomy 16 mouse model of down syndrome.

Cataldo AM, Petanceska S, Peterhoff CM, Terio NB, Epstein CJ, Villar A, Carlson EJ, Staufenbiel M, Nixon RA.

J Neurosci. 2003 Jul 30;23(17):6788-92.

14.

Beta-amyloid overload does not directly correlate with SAPK/JNK activation and tau protein phosphorylation in the cerebellar cortex of Ts65Dn mice.

Lomoio S, Scherini E, Necchi D.

Brain Res. 2009 Nov 10;1297:198-206. doi: 10.1016/j.brainres.2009.08.052. Epub 2009 Aug 21.

PMID:
19703431
15.

Reelin-immunoreactive Cajal-Retzius cells: the entorhinal cortex in normal aging and Alzheimer's disease.

Riedel A, Miettinen R, Stieler J, Mikkonen M, Alafuzoff I, Soininen H, Arendt T.

Acta Neuropathol. 2003 Oct;106(4):291-302. Epub 2003 Jun 17.

PMID:
12811583
16.

Reelin function in neural stem cell biology.

Kim HM, Qu T, Kriho V, Lacor P, Smalheiser N, Pappas GD, Guidotti A, Costa E, Sugaya K.

Proc Natl Acad Sci U S A. 2002 Mar 19;99(6):4020-5. Epub 2002 Mar 12.

17.

Reelin delays amyloid-beta fibril formation and rescues cognitive deficits in a model of Alzheimer's disease.

Pujadas L, Rossi D, Andrés R, Teixeira CM, Serra-Vidal B, Parcerisas A, Maldonado R, Giralt E, Carulla N, Soriano E.

Nat Commun. 2014 Mar 6;5:3443. doi: 10.1038/ncomms4443.

PMID:
24599114
18.

Constitutive Dyrk1A is abnormally expressed in Alzheimer disease, Down syndrome, Pick disease, and related transgenic models.

Ferrer I, Barrachina M, Puig B, Martínez de Lagrán M, Martí E, Avila J, Dierssen M.

Neurobiol Dis. 2005 Nov;20(2):392-400.

PMID:
16242644
19.

Reelin regulates neuronal progenitor migration in intact and epileptic hippocampus.

Gong C, Wang TW, Huang HS, Parent JM.

J Neurosci. 2007 Feb 21;27(8):1803-11.

20.

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