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Items: 1 to 20 of 101

1.

A large-scale, consortium-based genomewide association study of asthma.

Moffatt MF, Gut IG, Demenais F, Strachan DP, Bouzigon E, Heath S, von Mutius E, Farrall M, Lathrop M, Cookson WOCM.

N Engl J Med. 2010 Sep 23;363(13):1211-1221. doi: 10.1056/NEJMoa0906312.

2.

Genetic variants of 17q21 are associated with childhood-onset asthma and related phenotypes in a northeastern Han Chinese population: a case-control study.

Yu X, Yu C, Ren Z, Deng Y, Song J, Zhang H, Zhou H.

Tissue Antigens. 2014 May;83(5):330-6. doi: 10.1111/tan.12342. Epub 2014 Mar 21.

PMID:
24649901
3.

Functional variants of 17q12-21 are associated with allergic asthma but not allergic rhinitis.

Andiappan AK, Sio YY, Lee B, Suri BK, Matta SA, Lum J, Foo S, Koh G, Liu J, Zolezzi F, Poidinger M, Wang de Y, Rotzschke O, Chew FT.

J Allergy Clin Immunol. 2016 Mar;137(3):758-66.e3. doi: 10.1016/j.jaci.2015.08.038. Epub 2015 Oct 23.

PMID:
26483175
4.

Genetic effects of multiple asthma loci identified by genomewide association studies on asthma and spirometric indices.

Tang MF, Sy HY, Kong AP, Ko FW, Wang SS, Liu TC, Chan WC, Wong GW, Hon KL, Chan JC, Hui DS, Leung TF.

Pediatr Allergy Immunol. 2016 Mar;27(2):185-94. doi: 10.1111/pai.12505. Epub 2016 Jan 8.

PMID:
26534891
5.

Variants of DENND1B associated with asthma in children.

Sleiman PM, Flory J, Imielinski M, Bradfield JP, Annaiah K, Willis-Owen SA, Wang K, Rafaels NM, Michel S, Bonnelykke K, Zhang H, Kim CE, Frackelton EC, Glessner JT, Hou C, Otieno FG, Santa E, Thomas K, Smith RM, Glaberson WR, Garris M, Chiavacci RM, Beaty TH, Ruczinski I, Orange JS, Allen J, Spergel JM, Grundmeier R, Mathias RA, Christie JD, von Mutius E, Cookson WO, Kabesch M, Moffatt MF, Grunstein MM, Barnes KC, Devoto M, Magnusson M, Li H, Grant SF, Bisgaard H, Hakonarson H.

N Engl J Med. 2010 Jan 7;362(1):36-44. doi: 10.1056/NEJMoa0901867. Epub 2009 Dec 23. Erratum in: N Engl J Med. 2010 Sep 2;363(10):994. N Engl J Med. 2012 Feb 16;366(7):672. Orange, Jordan M [corrected to Orange, Jordan S].

6.

Polymorphisms related to ORMDL3 are associated with asthma susceptibility, alterations in transcriptional regulation of ORMDL3, and changes in TH2 cytokine levels.

Schedel M, Michel S, Gaertner VD, Toncheva AA, Depner M, Binia A, Schieck M, Rieger MT, Klopp N, von Berg A, Bufe A, Laub O, Rietschel E, Heinzmann A, Simma B, Vogelberg C, Genuneit J, Illig T, Kabesch M.

J Allergy Clin Immunol. 2015 Oct;136(4):893-903.e14. doi: 10.1016/j.jaci.2015.03.014. Epub 2015 Apr 28.

PMID:
25930191
7.

Relationship between the 17q21 locus and adult asthma in a Czech population.

Hrdlickova B, Holla LI.

Hum Immunol. 2011 Oct;72(10):921-5. doi: 10.1016/j.humimm.2011.07.309. Epub 2011 Aug 1.

PMID:
21843571
8.

Defining the contribution of SNPs identified in asthma GWAS to clinical variables in asthmatic children.

Tulah AS, Holloway JW, Sayers I.

BMC Med Genet. 2013 Sep 25;14:100. doi: 10.1186/1471-2350-14-100.

9.

Genome-wide association studies for discovery of genes involved in asthma.

Akhabir L, Sandford AJ.

Respirology. 2011 Apr;16(3):396-406. doi: 10.1111/j.1440-1843.2011.01939.x. Review.

PMID:
21276132
10.

Asthma and atopy are associated with chromosome 17q21 markers in Chinese children.

Leung TF, Sy HY, Ng MC, Chan IH, Wong GW, Tang NL, Waye MM, Lam CW.

Allergy. 2009 Apr;64(4):621-8. doi: 10.1111/j.1398-9995.2008.01873.x. Epub 2009 Jan 27.

11.

Association of IL33-IL-1 receptor-like 1 (IL1RL1) pathway polymorphisms with wheezing phenotypes and asthma in childhood.

Savenije OE, Mahachie John JM, Granell R, Kerkhof M, Dijk FN, de Jongste JC, Smit HA, Brunekreef B, Postma DS, Van Steen K, Henderson J, Koppelman GH.

J Allergy Clin Immunol. 2014 Jul;134(1):170-7. doi: 10.1016/j.jaci.2013.12.1080. Epub 2014 Feb 22.

PMID:
24568840
12.

IL33 and IL1RL1 variants are associated with asthma and atopy in a Brazilian population.

Queiroz GA, Costa RS, Alcantara-Neves NM, Nunes de Oliveira Costa G, Barreto ML, Carneiro VL, Figueiredo CA.

Int J Immunogenet. 2017 Apr;44(2):51-61. doi: 10.1111/iji.12306.

PMID:
28266165
13.

Effect of 17q21 variants and smoking exposure in early-onset asthma.

Bouzigon E, Corda E, Aschard H, Dizier MH, Boland A, Bousquet J, Chateigner N, Gormand F, Just J, Le Moual N, Scheinmann P, Siroux V, Vervloet D, Zelenika D, Pin I, Kauffmann F, Lathrop M, Demenais F.

N Engl J Med. 2008 Nov 6;359(19):1985-94. doi: 10.1056/NEJMoa0806604. Epub 2008 Oct 15.

14.

eQTL of bronchial epithelial cells and bronchial alveolar lavage deciphers GWAS-identified asthma genes.

Li X, Hastie AT, Hawkins GA, Moore WC, Ampleford EJ, Milosevic J, Li H, Busse WW, Erzurum SC, Kaminski N, Wenzel SE, Meyers DA, Bleecker ER.

Allergy. 2015 Oct;70(10):1309-18. doi: 10.1111/all.12683. Epub 2015 Jul 24.

15.

Genome-wide association study to identify genetic determinants of severe asthma.

Wan YI, Shrine NR, Soler Artigas M, Wain LV, Blakey JD, Moffatt MF, Bush A, Chung KF, Cookson WO, Strachan DP, Heaney L, Al-Momani BA, Mansur AH, Manney S, Thomson NC, Chaudhuri R, Brightling CE, Bafadhel M, Singapuri A, Niven R, Simpson A, Holloway JW, Howarth PH, Hui J, Musk AW, James AL; Australian Asthma Genetics Consortium, Brown MA, Baltic S, Ferreira MA, Thompson PJ, Tobin MD, Sayers I, Hall IP.

Thorax. 2012 Sep;67(9):762-8. Epub 2012 May 5.

16.

Polymorphisms in GSDMA and GSDMB are associated with asthma susceptibility, atopy and BHR.

Yu J, Kang MJ, Kim BJ, Kwon JW, Song YH, Choi WA, Shin YJ, Hong SJ.

Pediatr Pulmonol. 2011 Jul;46(7):701-8. doi: 10.1002/ppul.21424. Epub 2011 Feb 18.

PMID:
21337730
17.

A meta-analysis of genome-wide association studies for serum total IgE in diverse study populations.

Levin AM, Mathias RA, Huang L, Roth LA, Daley D, Myers RA, Himes BE, Romieu I, Yang M, Eng C, Park JE, Zoratti K, Gignoux CR, Torgerson DG, Galanter JM, Huntsman S, Nguyen EA, Becker AB, Chan-Yeung M, Kozyrskyj AL, Kwok PY, Gilliland FD, Gauderman WJ, Bleecker ER, Raby BA, Meyers DA, London SJ, Martinez FD, Weiss ST, Burchard EG, Nicolae DL, Ober C, Barnes KC, Williams LK.

J Allergy Clin Immunol. 2013 Apr;131(4):1176-84. doi: 10.1016/j.jaci.2012.10.002. Epub 2012 Nov 10.

18.

Association of genetic variants in chromosome 17q21 and adult-onset asthma in a Chinese Han population.

Fang Q, Zhao H, Wang A, Gong Y, Liu Q.

BMC Med Genet. 2011 Oct 11;12:133. doi: 10.1186/1471-2350-12-133.

19.

Genome-wide association study of asthma identifies RAD50-IL13 and HLA-DR/DQ regions.

Li X, Howard TD, Zheng SL, Haselkorn T, Peters SP, Meyers DA, Bleecker ER.

J Allergy Clin Immunol. 2010 Feb;125(2):328-335.e11. doi: 10.1016/j.jaci.2009.11.018.

20.

Human leukocyte antigen class II variants and adult-onset asthma: does occupational allergen exposure play a role?

Smit LA, Strachan DP, Vermeulen R, de Bakker PI, Demenais F, Dumas O, Carsin AE, Cullinan P, Curjuric I, Ghosh RE, Heederik D, Imboden M, Jarvis D, Lathrop M, Le Moual N, Mehta A, Miedinger D, Sigsgaard T, Siroux V, Vernez D, Zock JP, Kauffmann F, Probst-Hensch N, Kogevinas M, Bouzigon E.

Eur Respir J. 2014 Nov;44(5):1234-42. doi: 10.1183/09031936.00068014. Epub 2014 Jul 17.

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