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A responsive europium(III) chelate that provides a direct readout of pH by MRI.

Wu Y, Soesbe TC, Kiefer GE, Zhao P, Sherry AD.

J Am Chem Soc. 2010 Oct 13;132(40):14002-3. doi: 10.1021/ja106018n.


A europium(III)-based PARACEST agent for sensing singlet oxygen by MRI.

Song B, Wu Y, Yu M, Zhao P, Zhou C, Kiefer GE, Sherry AD.

Dalton Trans. 2013 Jun 14;42(22):8066-9. doi: 10.1039/c3dt50194a. Epub 2013 Apr 10.


Quantitative description of radiofrequency (RF) power-based ratiometric chemical exchange saturation transfer (CEST) pH imaging.

Wu R, Longo DL, Aime S, Sun PZ.

NMR Biomed. 2015 May;28(5):555-65. doi: 10.1002/nbm.3284. Epub 2015 Mar 23.


Paramagnetic lanthanide(III) complexes as pH-sensitive chemical exchange saturation transfer (CEST) contrast agents for MRI applications.

Aime S, Barge A, Delli Castelli D, Fedeli F, Mortillaro A, Nielsen FU, Terreno E.

Magn Reson Med. 2002 Apr;47(4):639-48.


A pH-Responsive MRI Agent that Can Be Activated Beyond the Tissue Magnetization Transfer Window.

Wang X, Wu Y, Soesbe TC, Yu J, Zhao P, Kiefer GE, Sherry AD.

Angew Chem Int Ed Engl. 2015 Jul 20;54(30):8662-4. doi: 10.1002/anie.201502497. Epub 2015 Jun 11.


Quantification of iopamidol multi-site chemical exchange properties for ratiometric chemical exchange saturation transfer (CEST) imaging of pH.

Sun PZ, Longo DL, Hu W, Xiao G, Wu R.

Phys Med Biol. 2014 Aug 21;59(16):4493-504. doi: 10.1088/0031-9155/59/16/4493. Epub 2014 Jul 23.


A general MRI-CEST ratiometric approach for pH imaging: demonstration of in vivo pH mapping with iobitridol.

Longo DL, Sun PZ, Consolino L, Michelotti FC, Uggeri F, Aime S.

J Am Chem Soc. 2014 Oct 15;136(41):14333-6. doi: 10.1021/ja5059313. Epub 2014 Oct 2.


Numerical solution of the Bloch equations provides insights into the optimum design of PARACEST agents for MRI.

Woessner DE, Zhang S, Merritt ME, Sherry AD.

Magn Reson Med. 2005 Apr;53(4):790-9.


A paramagnetic CEST agent for imaging glucose by MRI.

Zhang S, Trokowski R, Sherry AD.

J Am Chem Soc. 2003 Dec 17;125(50):15288-9.


A benzimidazole functionalised DO3A chelator showing pH switchable coordination modes with lanthanide ions.

Fisher CM, Fuller E, Burke BP, Mogilireddy V, Pope SJ, Sparke AE, Déchamps-Olivier I, Cadiou C, Chuburu F, Faulkner S, Archibald SJ.

Dalton Trans. 2014 Jul 7;43(25):9567-78. doi: 10.1039/c4dt00519h.


Europium(III) macrocyclic complexes with alcohol pendant groups as chemical exchange saturation transfer agents.

Woods M, Woessner DE, Zhao P, Pasha A, Yang MY, Huang CH, Vasalitiy O, Morrow JR, Sherry AD.

J Am Chem Soc. 2006 Aug 9;128(31):10155-62.


Oxidative Conversion of a Europium(II)-Based T1 Agent into a Europium(III)-Based paraCEST Agent that can be Detected In Vivo by Magnetic Resonance Imaging.

Funk AM, Clavijo Jordan V, Sherry AD, Ratnakar SJ, Kovacs Z.

Angew Chem Int Ed Engl. 2016 Apr 11;55(16):5024-7. doi: 10.1002/anie.201511649. Epub 2016 Mar 8.


Solution and solid-state characterization of Eu(II) chelates: a possible route towards redox responsive MRI contrast agents.

Burai L, Tóth E, Seibig S, Scopelliti R, Merbach AE.

Chemistry. 2000 Oct 16;6(20):3761-70.


Relaxation-compensated CEST-MRI at 7 T for mapping of creatine content and pH--preliminary application in human muscle tissue in vivo.

Rerich E, Zaiss M, Korzowski A, Ladd ME, Bachert P.

NMR Biomed. 2015 Nov;28(11):1402-12. doi: 10.1002/nbm.3367. Epub 2015 Sep 16.


Europium(III) DOTA-tetraamide complexes as redox-active MRI sensors.

Ratnakar SJ, Viswanathan S, Kovacs Z, Jindal AK, Green KN, Sherry AD.

J Am Chem Soc. 2012 Apr 4;134(13):5798-800. doi: 10.1021/ja211601k. Epub 2012 Mar 23.


Investigations into whole water, prototropic and amide proton exchange in lanthanide(III) DOTA-tetraamide chelates.

Woods M, Pasha A, Zhao P, Tircso G, Chowdhury S, Kiefer G, Woessner DE, Sherry AD.

Dalton Trans. 2011 Jul 7;40(25):6759-64. doi: 10.1039/c1dt10616c. Epub 2011 May 31.


A sensitive PARACEST contrast agent for temperature MRI: Eu3+-DOTAM-glycine (Gly)-phenylalanine (Phe).

Li AX, Wojciechowski F, Suchy M, Jones CK, Hudson RH, Menon RS, Bartha R.

Magn Reson Med. 2008 Feb;59(2):374-81. doi: 10.1002/mrm.21482.

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