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Items: 1 to 20 of 98

1.

PARP-1 regulates chromatin structure and transcription through a KDM5B-dependent pathway.

Krishnakumar R, Kraus WL.

Mol Cell. 2010 Sep 10;39(5):736-49. doi: 10.1016/j.molcel.2010.08.014.

2.

Reciprocal binding of PARP-1 and histone H1 at promoters specifies transcriptional outcomes.

Krishnakumar R, Gamble MJ, Frizzell KM, Berrocal JG, Kininis M, Kraus WL.

Science. 2008 Feb 8;319(5864):819-21. doi: 10.1126/science.1149250.

3.

Histone demethylase KDM5B is a key regulator of genome stability.

Li X, Liu L, Yang S, Song N, Zhou X, Gao J, Yu N, Shan L, Wang Q, Liang J, Xuan C, Wang Y, Shang Y, Shi L.

Proc Natl Acad Sci U S A. 2014 May 13;111(19):7096-101. doi: 10.1073/pnas.1324036111. Epub 2014 Apr 28.

4.

Global Transcriptome Analysis Reveals That Poly(ADP-Ribose) Polymerase 1 Regulates Gene Expression through EZH2.

Martin KA, Cesaroni M, Denny MF, Lupey LN, Tempera I.

Mol Cell Biol. 2015 Dec;35(23):3934-44. doi: 10.1128/MCB.00635-15. Epub 2015 Sep 14.

5.

PARP-2 regulates cell cycle-related genes through histone deacetylation and methylation independently of poly(ADP-ribosyl)ation.

Liang YC, Hsu CY, Yao YL, Yang WM.

Biochem Biophys Res Commun. 2013 Feb 1;431(1):58-64. doi: 10.1016/j.bbrc.2012.12.092. Epub 2013 Jan 3.

PMID:
23291187
6.

Poly(ADP-ribose) polymerase 1 is inhibited by a histone H2A variant, MacroH2A, and contributes to silencing of the inactive X chromosome.

Nusinow DA, Hernández-Muñoz I, Fazzio TG, Shah GM, Kraus WL, Panning B.

J Biol Chem. 2007 Apr 27;282(17):12851-9. Epub 2007 Feb 23.

7.

Studies of H3K4me3 demethylation by KDM5B/Jarid1B/PLU1 reveals strong substrate recognition in vitro and identifies 2,4-pyridine-dicarboxylic acid as an in vitro and in cell inhibitor.

Kristensen LH, Nielsen AL, Helgstrand C, Lees M, Cloos P, Kastrup JS, Helin K, Olsen L, Gajhede M.

FEBS J. 2012 Jun;279(11):1905-14. doi: 10.1111/j.1742-4658.2012.08567.x. Epub 2012 May 2.

8.

Poly(ADP-ribose) Polymerase 1 Interacts with Nuclear Respiratory Factor 1 (NRF-1) and Plays a Role in NRF-1 Transcriptional Regulation.

Hossain MB, Ji P, Anish R, Jacobson RH, Takada S.

J Biol Chem. 2009 Mar 27;284(13):8621-32. doi: 10.1074/jbc.M807198200. Epub 2009 Jan 30.

9.

Poly(ADP-ribose) polymerase-1 modulates Nrf2-dependent transcription.

Wu T, Wang XJ, Tian W, Jaramillo MC, Lau A, Zhang DD.

Free Radic Biol Med. 2014 Feb;67:69-80. doi: 10.1016/j.freeradbiomed.2013.10.806. Epub 2013 Oct 17.

10.

SUMOylation negatively modulates target gene occupancy of the KDM5B, a histone lysine demethylase.

Bueno MT, Richard S.

Epigenetics. 2013 Nov;8(11):1162-75. doi: 10.4161/epi.26112. Epub 2013 Aug 22.

PMID:
23970103
11.

Histone H1 poly[ADP]-ribosylation regulates the chromatin alterations required for learning consolidation.

Fontán-Lozano A, Suárez-Pereira I, Horrillo A, del-Pozo-Martín Y, Hmadcha A, Carrión AM.

J Neurosci. 2010 Oct 6;30(40):13305-13. doi: 10.1523/JNEUROSCI.3010-10.2010.

12.

Poly(ADP-ribosyl)ation is required to modulate chromatin changes at c-MYC promoter during emergence from quiescence.

Mostocotto C, Carbone M, Battistelli C, Ciotti A, Amati P, Maione R.

PLoS One. 2014 Jul 21;9(7):e102575. doi: 10.1371/journal.pone.0102575. eCollection 2014.

13.

KDM5B focuses H3K4 methylation near promoters and enhancers during embryonic stem cell self-renewal and differentiation.

Kidder BL, Hu G, Zhao K.

Genome Biol. 2014 Feb 4;15(2):R32. doi: 10.1186/gb-2014-15-2-r32.

14.

Four enzymes cooperate to displace histone H1 during the first minute of hormonal gene activation.

Vicent GP, Nacht AS, Font-Mateu J, Castellano G, Gaveglia L, Ballaré C, Beato M.

Genes Dev. 2011 Apr 15;25(8):845-62. doi: 10.1101/gad.621811. Epub 2011 Mar 29.

15.

The histone-H3K4-specific demethylase KDM5B binds to its substrate and product through distinct PHD fingers.

Klein BJ, Piao L, Xi Y, Rincon-Arano H, Rothbart SB, Peng D, Wen H, Larson C, Zhang X, Zheng X, Cortazar MA, Peña PV, Mangan A, Bentley DL, Strahl BD, Groudine M, Li W, Shi X, Kutateladze TG.

Cell Rep. 2014 Jan 30;6(2):325-35. doi: 10.1016/j.celrep.2013.12.021. Epub 2014 Jan 9.

16.

The DNA binding and catalytic domains of poly(ADP-ribose) polymerase 1 cooperate in the regulation of chromatin structure and transcription.

Wacker DA, Ruhl DD, Balagamwala EH, Hope KM, Zhang T, Kraus WL.

Mol Cell Biol. 2007 Nov;27(21):7475-85. Epub 2007 Sep 4.

17.

Transcriptional regulation of mouse mu opioid receptor gene in neuronal cells by poly(ADP-ribose) polymerase-1.

Choi HS, Hwang CK, Kim CS, Song KY, Law PY, Loh HH, Wei LN.

J Cell Mol Med. 2008 Dec;12(6A):2319-33. doi: 10.1111/j.1582-4934.2008.00259.x. Epub 2008 Feb 4.

18.

PARP goes transcription.

Kraus WL, Lis JT.

Cell. 2003 Jun 13;113(6):677-83. Review.

19.

PARP-14 functions as a transcriptional switch for Stat6-dependent gene activation.

Mehrotra P, Riley JP, Patel R, Li F, Voss L, Goenka S.

J Biol Chem. 2011 Jan 21;286(3):1767-76. doi: 10.1074/jbc.M110.157768. Epub 2010 Nov 16.

20.

The histone variant mH2A1.1 interferes with transcription by down-regulating PARP-1 enzymatic activity.

Ouararhni K, Hadj-Slimane R, Ait-Si-Ali S, Robin P, Mietton F, Harel-Bellan A, Dimitrov S, Hamiche A.

Genes Dev. 2006 Dec 1;20(23):3324-36.

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