Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 101


Application of an assay for 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) in urine for the assessment of tobacco-related harm.

Lu W, Ferguson SG, Nichols DS, Patel R, Jacobson GA.

J Pharm Biomed Anal. 2016 Nov 30;131:327-332. doi: 10.1016/j.jpba.2016.08.013. Epub 2016 Aug 16.


A new liquid chromatography/mass spectrometry method for 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) in urine.

Bhat SH, Gelhaus SL, Mesaros C, Vachani A, Blair IA.

Rapid Commun Mass Spectrom. 2011 Jan 15;25(1):115-21. doi: 10.1002/rcm.4824.


Direct analysis of tobacco-specific nitrosamine NNK and its metabolite NNAL in human urine by LC-MS/MS: evidence of linkage to methylated DNA lesions.

Hu CW, Hsu YW, Chen JL, Tam LM, Chao MR.

Arch Toxicol. 2014 Feb;88(2):291-9. doi: 10.1007/s00204-013-1137-y. Epub 2013 Sep 22.


Analysis of human urine for pyridine-N-oxide metabolites of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, a tobacco-specific lung carcinogen.

Carmella SG, Borukhova A, Akerkar SA, Hecht SS.

Cancer Epidemiol Biomarkers Prev. 1997 Feb;6(2):113-20.


Genetic variability in the metabolism of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) to 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL).

Ter-Minassian M, Asomaning K, Zhao Y, Chen F, Su L, Carmella SG, Lin X, Hecht SS, Christiani DC.

Int J Cancer. 2012 Mar 15;130(6):1338-46. doi: 10.1002/ijc.26162. Epub 2011 Aug 3.


High throughput liquid and gas chromatography-tandem mass spectrometry assays for tobacco-specific nitrosamine and polycyclic aromatic hydrocarbon metabolites associated with lung cancer in smokers.

Carmella SG, Ming X, Olvera N, Brookmeyer C, Yoder A, Hecht SS.

Chem Res Toxicol. 2013 Aug 19;26(8):1209-17. doi: 10.1021/tx400121n. Epub 2013 Jul 24.


Low ratio of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol-glucuronides (NNAL-Gluc)/free NNAL increases urothelial carcinoma risk.

Chung CJ, Lee HL, Yang HY, Lin P, Pu YS, Shiue HS, Su CT, Hsueh YM.

Sci Total Environ. 2011 Apr 1;409(9):1638-42. doi: 10.1016/j.scitotenv.2011.01.046. Epub 2011 Feb 21.


Analysis of total 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) in human urine.

Carmella SG, Han S, Fristad A, Yang Y, Hecht SS.

Cancer Epidemiol Biomarkers Prev. 2003 Nov;12(11 Pt 1):1257-61.


Tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) in smokers in the United States: NHANES 2007-2008.

Xia Y, Bernert JT, Jain RB, Ashley DL, Pirkle JL.

Biomarkers. 2011 Mar;16(2):112-9. doi: 10.3109/1354750X.2010.533288. Epub 2010 Nov 29.


Metabolites of a tobacco-specific nitrosamine, 4-(methylnitrosamino)- 1-(3-pyridyl)-1-butanone (NNK), in the urine of smokeless tobacco users: relationship between urinary biomarkers and oral leukoplakia.

Kresty LA, Carmella SG, Borukhova A, Akerkar SA, Gopalakrishnan R, Harris RE, Stoner GD, Hecht SS.

Cancer Epidemiol Biomarkers Prev. 1996 Jul;5(7):521-5.


Urinary levels of the tobacco-specific carcinogen N'-nitrosonornicotine and its glucuronide are strongly associated with esophageal cancer risk in smokers.

Yuan JM, Knezevich AD, Wang R, Gao YT, Hecht SS, Stepanov I.

Carcinogenesis. 2011 Sep;32(9):1366-71. doi: 10.1093/carcin/bgr125. Epub 2011 Jul 6.


Combined analysis of the tobacco metabolites cotinine and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol in human urine.

Kotandeniya D, Carmella SG, Ming X, Murphy SE, Hecht SS.

Anal Chem. 2015 Feb 3;87(3):1514-7. doi: 10.1021/ac504047j. Epub 2015 Jan 14.


Uptake and metabolism of carcinogenic levels of tobacco-specific nitrosamines by Sudanese snuff dippers.

Murphy SE, Carmella SG, Idris AM, Hoffmann D.

Cancer Epidemiol Biomarkers Prev. 1994 Jul-Aug;3(5):423-8.


4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol and its glucuronides in the urine of infants exposed to environmental tobacco smoke.

Hecht SS, Carmella SG, Le KA, Murphy SE, Boettcher AJ, Le C, Koopmeiners J, An L, Hennrikus DJ.

Cancer Epidemiol Biomarkers Prev. 2006 May;15(5):988-92.


Metabolism of the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone to its biomarker total NNAL in smokeless tobacco users.

Hecht SS, Carmella SG, Stepanov I, Jensen J, Anderson A, Hatsukami DK.

Cancer Epidemiol Biomarkers Prev. 2008 Mar;17(3):732-5. doi: 10.1158/1055-9965.EPI-07-2843.


Comparison of creatinine and specific gravity for hydration corrections on measurement of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) in urine.

Xia Y, Wong LY, Bunker BC, Bernert JT.

J Clin Lab Anal. 2014 Sep;28(5):353-63. doi: 10.1002/jcla.21693. Epub 2014 Mar 19.


Correlation between the urine profile of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone metabolites and N7-methylguanine in urothelial carcinoma patients.

Lee HL, Hsueh YM, Chung CJ, Pu YS, Chang LW, Hsieh DP, Liou SH, Lin P.

Cancer Epidemiol Biomarkers Prev. 2008 Dec;17(12):3390-5. doi: 10.1158/1055-9965.EPI-08-0761. Erratum in: Cancer Epidemiol Biomarkers Prev. 2009 Jan;18(1):361.

Supplemental Content

Support Center