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Items: 1 to 20 of 79

1.

Methylerythritol cyclodiphosphate (MEcPP) in deoxyxylulose phosphate pathway: synthesis from an epoxide and mechanisms.

Xiao Y, Nyland RL 2nd, Meyers CL, Liu P.

Chem Commun (Camb). 2010 Oct 14;46(38):7220-2. doi: 10.1039/c0cc02594a. Epub 2010 Sep 1.

2.

IspG-catalyzed positional isotopic exchange in methylerythritol cyclodiphosphate of the deoxyxylulose phosphate pathway: mechanistic implications.

Xiao Y, Rooker D, You Q, Meyers CL, Liu P.

Chembiochem. 2011 Mar 7;12(4):527-30. doi: 10.1002/cbic.201000716. Epub 2011 Jan 26.

3.

IspG converts an epoxide substrate analogue to (E)-4-hydroxy-3-methylbut-2-enyl diphosphate: implications for IspG catalysis in isoprenoid biosynthesis.

Nyland RL 2nd, Xiao Y, Liu P, Freel Meyers CL.

J Am Chem Soc. 2009 Dec 16;131(49):17734-5. doi: 10.1021/ja907470n.

4.

Structure of the GcpE-HMBPP complex from Thermus thermophilius.

Rekittke I, Warkentin E, Jomaa H, Ermler U.

Biochem Biophys Res Commun. 2015 Mar 6;458(2):246-50. doi: 10.1016/j.bbrc.2015.01.088. Epub 2015 Feb 7.

PMID:
25660452
5.

Methylerythritol phosphate pathway to isoprenoids: kinetic modeling and in silico enzyme inhibitions in Plasmodium falciparum.

Singh VK, Ghosh I.

FEBS Lett. 2013 Sep 2;587(17):2806-17. doi: 10.1016/j.febslet.2013.06.024. Epub 2013 Jun 28.

6.

Paramagnetic intermediates of (E)-4-hydroxy-3-methylbut-2-enyl diphosphate synthase (GcpE/IspG) under steady-state and pre-steady-state conditions.

Xu W, Lees NS, Adedeji D, Wiesner J, Jomaa H, Hoffman BM, Duin EC.

J Am Chem Soc. 2010 Oct 20;132(41):14509-20. doi: 10.1021/ja101764w.

PMID:
20863107
7.

Study of IspH, a key enzyme in the methylerythritol phosphate pathway using fluoro-substituted substrate analogues.

Xiao Y, Chang WC, Liu HW, Liu P.

Org Lett. 2011 Nov 4;13(21):5912-5. doi: 10.1021/ol202559r. Epub 2011 Oct 7.

8.

Accumulation of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate in illuminated plant leaves at supraoptimal temperatures reveals a bottleneck of the prokaryotic methylerythritol 4-phosphate pathway of isoprenoid biosynthesis.

Rivasseau C, Seemann M, Boisson AM, Streb P, Gout E, Douce R, Rohmer M, Bligny R.

Plant Cell Environ. 2009 Jan;32(1):82-92. doi: 10.1111/j.1365-3040.2008.01903.x. Epub 2008 Nov 10.

9.

Structure of the GcpE (IspG)-MEcPP complex from Thermus thermophilus.

Rekittke I, Jomaa H, Ermler U.

FEBS Lett. 2012 Sep 21;586(19):3452-7. doi: 10.1016/j.febslet.2012.07.070. Epub 2012 Aug 9.

10.

The deoxyxylulose phosphate pathway of isoprenoid biosynthesis: studies on the mechanisms of the reactions catalyzed by IspG and IspH protein.

Rohdich F, Zepeck F, Adam P, Hecht S, Kaiser J, Laupitz R, Gräwert T, Amslinger S, Eisenreich W, Bacher A, Arigoni D.

Proc Natl Acad Sci U S A. 2003 Feb 18;100(4):1586-91. Epub 2003 Feb 5.

11.

Isoprenoid biosynthesis in plant chloroplasts via the MEP pathway: direct thylakoid/ferredoxin-dependent photoreduction of GcpE/IspG.

Seemann M, Tse Sum Bui B, Wolff M, Miginiac-Maslow M, Rohmer M.

FEBS Lett. 2006 Mar 6;580(6):1547-52. Epub 2006 Feb 2.

13.

Metabolite profiling of plastidial deoxyxylulose-5-phosphate pathway intermediates by liquid chromatography and mass spectrometry.

Baidoo EE, Xiao Y, Dehesh K, Keasling JD.

Methods Mol Biol. 2014;1153:57-76. doi: 10.1007/978-1-4939-0606-2_5.

15.

Functional analysis of the final steps of the 1-deoxy-D-xylulose 5-phosphate (DXP) pathway to isoprenoids in plants using virus-induced gene silencing.

Page JE, Hause G, Raschke M, Gao W, Schmidt J, Zenk MH, Kutchan TM.

Plant Physiol. 2004 Apr;134(4):1401-13. Epub 2004 Apr 2.

16.
17.

IspH protein of the deoxyxylulose phosphate pathway: mechanistic studies with C1-deuterium-labeled substrate and fluorinated analogue.

Xiao Y, Liu P.

Angew Chem Int Ed Engl. 2008;47(50):9722-5. doi: 10.1002/anie.200803452. No abstract available.

PMID:
18980164
18.

Synthesis of 2-methyl-D-erythritol via epoxy ester-orthoester rearrangement.

Giner JL, Ferris WV Jr, Mullins JJ.

J Org Chem. 2002 Jul 12;67(14):4856-9.

PMID:
12098298
19.

The biosynthesis of C5-C25 terpenoid compounds.

Dewick PM.

Nat Prod Rep. 2002 Apr;19(2):181-222. Review.

PMID:
12013278
20.

Aliphatic epoxide carboxylation.

Ensign SA, Allen JR.

Annu Rev Biochem. 2003;72:55-76. Epub 2003 Jan 8. Review.

PMID:
12524213

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