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Items: 1 to 20 of 89


Human single-nucleotide polymorphisms alter p53 sequence-specific binding at gene regulatory elements.

Bandele OJ, Wang X, Campbell MR, Pittman GS, Bell DA.

Nucleic Acids Res. 2011 Jan;39(1):178-89. doi: 10.1093/nar/gkq764. Epub 2010 Sep 3.


Interactions of chromatin context, binding site sequence content, and sequence evolution in stress-induced p53 occupancy and transactivation.

Su D, Wang X, Campbell MR, Song L, Safi A, Crawford GE, Bell DA.

PLoS Genet. 2015 Jan 8;11(1):e1004885. doi: 10.1371/journal.pgen.1004885. eCollection 2015 Jan.


Probing the functional impact of sequence variation on p53-DNA interactions using a novel microsphere assay for protein-DNA binding with human cell extracts.

Noureddine MA, Menendez D, Campbell MR, Bandele OJ, Horvath MM, Wang X, Pittman GS, Chorley BN, Resnick MA, Bell DA.

PLoS Genet. 2009 May;5(5):e1000462. doi: 10.1371/journal.pgen.1000462. Epub 2009 May 8.


Functionally distinct polymorphic sequences in the human genome that are targets for p53 transactivation.

Tomso DJ, Inga A, Menendez D, Pittman GS, Campbell MR, Storici F, Bell DA, Resnick MA.

Proc Natl Acad Sci U S A. 2005 May 3;102(18):6431-6. Epub 2005 Apr 20.


Linking polymorphic p53 response elements with gene expression in airway epithelial cells of smokers and cancer risk.

Wang X, Pittman GS, Bandele OJ, Bischof JJ, Liu G, Brothers JF 2nd, Spira A, Bell DA.

Hum Genet. 2014 Dec;133(12):1467-76. doi: 10.1007/s00439-014-1483-8. Epub 2014 Sep 2.


A SNP in the flt-1 promoter integrates the VEGF system into the p53 transcriptional network.

Menendez D, Krysiak O, Inga A, Krysiak B, Resnick MA, Schönfelder G.

Proc Natl Acad Sci U S A. 2006 Jan 31;103(5):1406-11. Epub 2006 Jan 23.


Divergent evolution of human p53 binding sites: cell cycle versus apoptosis.

Horvath MM, Wang X, Resnick MA, Bell DA.

PLoS Genet. 2007 Jul;3(7):e127. Epub 2007 Jun 15.


Impact of Alu repeats on the evolution of human p53 binding sites.

Cui F, Sirotin MV, Zhurkin VB.

Biol Direct. 2011 Jan 6;6:2. doi: 10.1186/1745-6150-6-2.


Functional diversity in the gene network controlled by the master regulator p53 in humans.

Resnick MA, Tomso D, Inga A, Menendez D, Bell D.

Cell Cycle. 2005 Aug;4(8):1026-9. Epub 2005 Aug 7. Review.


Regression based predictor for p53 transactivation.

Gowrisankar S, Jegga AG.

BMC Bioinformatics. 2009 Jul 14;10:215. doi: 10.1186/1471-2105-10-215.


Whole-genome cartography of p53 response elements ranked on transactivation potential.

Tebaldi T, Zaccara S, Alessandrini F, Bisio A, Ciribilli Y, Inga A.

BMC Genomics. 2015 Jun 17;16:464. doi: 10.1186/s12864-015-1643-9.


Formation of stress-specific p53 binding patterns is influenced by chromatin but not by modulation of p53 binding affinity to response elements.

Millau JF, Bandele OJ, Perron J, Bastien N, Bouchard EF, Gaudreau L, Bell DA, Drouin R.

Nucleic Acids Res. 2011 Apr;39(8):3053-63. doi: 10.1093/nar/gkq1209. Epub 2010 Dec 21.


Transcriptional modulation induced by ionizing radiation: p53 remains a central player.

Rashi-Elkeles S, Elkon R, Shavit S, Lerenthal Y, Linhart C, Kupershtein A, Amariglio N, Rechavi G, Shamir R, Shiloh Y.

Mol Oncol. 2011 Aug;5(4):336-48. doi: 10.1016/j.molonc.2011.06.004. Epub 2011 Jul 7. Review.


Redefining the p53 response element.

Wang B, Xiao Z, Ren EC.

Proc Natl Acad Sci U S A. 2009 Aug 25;106(34):14373-8. doi: 10.1073/pnas.0903284106. Epub 2009 Jul 13. Erratum in: Proc Natl Acad Sci U S A. 2009 Sep 29;106(39):16890.


Mapping the p53 transcriptome universe using p53 natural polymorphs.

Wang B, Niu D, Lam TH, Xiao Z, Ren EC.

Cell Death Differ. 2014 Apr;21(4):521-32. doi: 10.1038/cdd.2013.132. Epub 2013 Sep 27.


The effect of non-coding DNA variations on P53 and cMYC competitive inhibition at cis-overlapping motifs.

Kin K, Chen X, Gonzalez-Garay M, Fakhouri WD.

Hum Mol Genet. 2016 Apr 15;25(8):1517-27. doi: 10.1093/hmg/ddw030. Epub 2016 Feb 7.


A single-nucleotide polymorphism in a half-binding site creates p53 and estrogen receptor control of vascular endothelial growth factor receptor 1.

Menendez D, Inga A, Snipe J, Krysiak O, Schönfelder G, Resnick MA.

Mol Cell Biol. 2007 Apr;27(7):2590-600. Epub 2007 Jan 22.


p53 Binding to the p21 promoter is dependent on the nature of DNA damage.

Hill R, Bodzak E, Blough MD, Lee PW.

Cell Cycle. 2008 Aug 15;7(16):2535-43. Epub 2008 Aug 12.


Comprehensive Expression Profiling and Functional Network Analysis of p53-Regulated MicroRNAs in HepG2 Cells Treated with Doxorubicin.

Yang Y, Liu W, Ding R, Xiong L, Dou R, Zhang Y, Guo Z.

PLoS One. 2016 Feb 17;11(2):e0149227. doi: 10.1371/journal.pone.0149227. eCollection 2016.

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