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Items: 1 to 20 of 92

1.

Structural control of cytochrome P450-catalyzed ω-hydroxylation.

Johnston JB, Ouellet H, Podust LM, Ortiz de Montellano PR.

Arch Biochem Biophys. 2011 Mar 1;507(1):86-94. doi: 10.1016/j.abb.2010.08.011. Epub 2010 Aug 19. Review.

2.

Molecular Dynamics and QM/MM Calculations Predict the Substrate-Induced Gating of Cytochrome P450 BM3 and the Regio- and Stereoselectivity of Fatty Acid Hydroxylation.

Dubey KD, Wang B, Shaik S.

J Am Chem Soc. 2016 Jan 27;138(3):837-45. doi: 10.1021/jacs.5b08737. Epub 2016 Jan 13.

PMID:
26716578
3.

Fatty acid discrimination and omega-hydroxylation by cytochrome P450 4A1 and a cytochrome P4504A1/NADPH-P450 reductase fusion protein.

Alterman MA, Chaurasia CS, Lu P, Hardwick JP, Hanzlik RP.

Arch Biochem Biophys. 1995 Jul 10;320(2):289-96.

PMID:
7625836
4.

A natural heme-signature variant of CYP267A1 from Sorangium cellulosum So ce56 executes diverse ω-hydroxylation.

Khatri Y, Hannemann F, Girhard M, Kappl R, Hutter M, Urlacher VB, Bernhardt R.

FEBS J. 2015 Jan;282(1):74-88. doi: 10.1111/febs.13104. Epub 2014 Nov 4.

5.

Mechanism and role of covalent heme binding in the CYP4 family of P450 enzymes and the mammalian peroxidases.

Ortiz de Montellano PR.

Drug Metab Rev. 2008;40(3):405-26. doi: 10.1080/03602530802186439 . Review.

PMID:
18642140
6.

Expression, purification and characterization of cytochrome P450 Biol: a novel P450 involved in biotin synthesis in Bacillus subtilis.

Green AJ, Rivers SL, Cheeseman M, Reid GA, Quaroni LG, Macdonald ID, Chapman SK, Munro AW.

J Biol Inorg Chem. 2001 Jun;6(5-6):523-33.

PMID:
11472016
7.
8.

Products of cytochrome P450(BioI) (CYP107H1)-catalyzed oxidation of fatty acids.

Cryle MJ, Matovic NJ, De Voss JJ.

Org Lett. 2003 Sep 4;5(18):3341-4.

PMID:
12943422
9.

Substrate recognition and molecular mechanism of fatty acid hydroxylation by cytochrome P450 from Bacillus subtilis. Crystallographic, spectroscopic, and mutational studies.

Lee DS, Yamada A, Sugimoto H, Matsunaga I, Ogura H, Ichihara K, Adachi S, Park SY, Shiro Y.

J Biol Chem. 2003 Mar 14;278(11):9761-7. Epub 2003 Jan 7.

10.

Regioselective hydroxylation of C(12)-C(15) fatty acids with fluorinated substituents by cytochrome P450 BM3.

Chiang CH, Ramu R, Tu YJ, Yang CL, Ng KY, Luo WI, Chen CH, Lu YY, Liu CL, Yu SS.

Chemistry. 2013 Oct 4;19(41):13680-91. doi: 10.1002/chem.201302402. Epub 2013 Sep 11.

PMID:
24092541
11.

CYP94A5, a new cytochrome P450 from Nicotiana tabacum is able to catalyze the oxidation of fatty acids to the omega-alcohol and to the corresponding diacid.

Le Bouquin R, Skrabs M, Kahn R, Benveniste I, Salaün JP, Schreiber L, Durst F, Pinot F.

Eur J Biochem. 2001 May;268(10):3083-90.

13.

Oxidation of fatty acids by kidney microsomes of musk shrew (Suncus murinus).

Miura Y, Oda S.

Comp Biochem Physiol B Biochem Mol Biol. 1998 Jan;119(1):107-12.

PMID:
9530812
14.

Different mechanisms of regioselection of fatty acid hydroxylation by laurate (omega-1)-hydroxylating P450s, P450 2C2 and P450 2E1.

Fukuda T, Imai Y, Komori M, Nakamura M, Kusunose E, Satouchi K, Kusunose M.

J Biochem. 1994 Feb;115(2):338-44.

15.

Omega oxygenases: nonheme-iron enzymes and P450 cytochromes.

Coon MJ.

Biochem Biophys Res Commun. 2005 Dec 9;338(1):378-85. Epub 2005 Aug 30. Review.

PMID:
16165094
16.

Are branched chain fatty acids the natural substrates for P450(BM3)?

Cryle MJ, Espinoza RD, Smith SJ, Matovic NJ, De Voss JJ.

Chem Commun (Camb). 2006 Jun 14;(22):2353-5. Epub 2006 Mar 30.

PMID:
16733577
17.

Positional specificity of rabbit CYP4B1 for omega-hydroxylation1 of short-medium chain fatty acids and hydrocarbons.

Fisher MB, Zheng YM, Rettie AE.

Biochem Biophys Res Commun. 1998 Jul 20;248(2):352-5.

PMID:
9675139
19.
20.

Cytochrome P450BM-3 (CYP102): regiospecificity of oxidation of omega-unsaturated fatty acids and mechanism-based inactivation.

Shirane N, Sui Z, Peterson JA, Ortiz de Montellano PR.

Biochemistry. 1993 Dec 14;32(49):13732-41.

PMID:
8257708

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