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Items: 1 to 20 of 122

1.

Common genetic variation in Neuregulin 3 (NRG3) influences risk for schizophrenia and impacts NRG3 expression in human brain.

Kao WT, Wang Y, Kleinman JE, Lipska BK, Hyde TM, Weinberger DR, Law AJ.

Proc Natl Acad Sci U S A. 2010 Aug 31;107(35):15619-24. doi: 10.1073/pnas.1005410107. Epub 2010 Aug 16.

2.

Temporal, Diagnostic, and Tissue-Specific Regulation of NRG3 Isoform Expression in Human Brain Development and Affective Disorders.

Paterson C, Wang Y, Hyde TM, Weinberger DR, Kleinman JE, Law AJ.

Am J Psychiatry. 2017 Mar 1;174(3):256-265. doi: 10.1176/appi.ajp.2016.16060721. Epub 2016 Oct 24.

PMID:
27771971
3.

Neuregulin 3 (NRG3) as a susceptibility gene in a schizophrenia subtype with florid delusions and relatively spared cognition.

Morar B, Dragović M, Waters FA, Chandler D, Kalaydjieva L, Jablensky A.

Mol Psychiatry. 2011 Aug;16(8):860-6. doi: 10.1038/mp.2010.70. Epub 2010 Jun 15.

PMID:
20548296
4.

Fine mapping on chromosome 10q22-q23 implicates Neuregulin 3 in schizophrenia.

Chen PL, Avramopoulos D, Lasseter VK, McGrath JA, Fallin MD, Liang KY, Nestadt G, Feng N, Steel G, Cutting AS, Wolyniec P, Pulver AE, Valle D.

Am J Hum Genet. 2009 Jan;84(1):21-34. doi: 10.1016/j.ajhg.2008.12.005.

5.

Effects of neuregulin 3 genotype on human prefrontal cortex physiology.

Tost H, Callicott JH, Rasetti R, Vakkalanka R, Mattay VS, Weinberger DR, Law AJ.

J Neurosci. 2014 Jan 15;34(3):1051-6. doi: 10.1523/JNEUROSCI.3496-13.2014.

6.

Transient overexposure of neuregulin 3 during early postnatal development impacts selective behaviors in adulthood.

Paterson C, Law AJ.

PLoS One. 2014 Aug 5;9(8):e104172. doi: 10.1371/journal.pone.0104172. eCollection 2014.

7.

Evidence from mouse and man for a role of neuregulin 3 in nicotine dependence.

Turner JR, Ray R, Lee B, Everett L, Xiang J, Jepson C, Kaestner KH, Lerman C, Blendy JA.

Mol Psychiatry. 2014 Jul;19(7):801-10. doi: 10.1038/mp.2013.104. Epub 2013 Sep 3.

8.

Neuregulin 3 does not confer risk for schizophrenia and smooth pursuit eye movement abnormality in a Korean population.

Pasaje CF, Bae JS, Park BL, Cheong HS, Kim JH, Park TJ, Lee JS, Kim Y, Park CS, Kim BJ, Cha B, Kim JW, Choi WH, Shin TM, Choi IG, Hwang J, Shin HD, Woo SI.

Genes Brain Behav. 2011 Nov;10(8):828-33. doi: 10.1111/j.1601-183X.2011.00722.x. Epub 2011 Aug 9.

9.

Expression of ZNF804A in human brain and alterations in schizophrenia, bipolar disorder, and major depressive disorder: a novel transcript fetally regulated by the psychosis risk variant rs1344706.

Tao R, Cousijn H, Jaffe AE, Burnet PW, Edwards F, Eastwood SL, Shin JH, Lane TA, Walker MA, Maher BJ, Weinberger DR, Harrison PJ, Hyde TM, Kleinman JE.

JAMA Psychiatry. 2014 Oct;71(10):1112-20. doi: 10.1001/jamapsychiatry.2014.1079.

PMID:
25162540
10.

Disease-associated intronic variants in the ErbB4 gene are related to altered ErbB4 splice-variant expression in the brain in schizophrenia.

Law AJ, Kleinman JE, Weinberger DR, Weickert CS.

Hum Mol Genet. 2007 Jan 15;16(2):129-41. Epub 2006 Dec 12.

PMID:
17164265
11.

NRG3 gene is associated with the risk and age at onset of Alzheimer disease.

Wang KS, Xu N, Wang L, Aragon L, Ciubuc R, Arana TB, Mao C, Petty L, Briones D, Su BB, Luo X, Camarillo C, Escamilla MA, Xu C.

J Neural Transm (Vienna). 2014 Feb;121(2):183-92. doi: 10.1007/s00702-013-1091-0. Epub 2013 Sep 24.

PMID:
24061483
12.

Neuregulin 3 genetic variations and susceptibility to schizophrenia in a Chinese population.

Wang YC, Chen JY, Chen ML, Chen CH, Lai IC, Chen TT, Hong CJ, Tsai SJ, Liou YJ.

Biol Psychiatry. 2008 Dec 15;64(12):1093-6. doi: 10.1016/j.biopsych.2008.07.012. Epub 2008 Aug 16.

PMID:
18708184
13.

Neuregulin-3 (NRG3): a novel neural tissue-enriched protein that binds and activates ErbB4.

Zhang D, Sliwkowski MX, Mark M, Frantz G, Akita R, Sun Y, Hillan K, Crowley C, Brush J, Godowski PJ.

Proc Natl Acad Sci U S A. 1997 Sep 2;94(18):9562-7.

14.

No genetic evidence for Neuregulin 3 conferring risk of schizophrenia in the Chinese population.

Zhang R, Du XY, Yu J, Xu N, Zheng YW, Zhao YL, Zhang H, Ma J.

Psychiatry Res. 2013 Feb 28;205(3):279-81. doi: 10.1016/j.psychres.2012.08.017. Epub 2012 Sep 13.

PMID:
22981155
15.

Neuregulin 3 is associated with attention deficits in schizophrenia and bipolar disorder.

Meier S, Strohmaier J, Breuer R, Mattheisen M, Degenhardt F, Mühleisen TW, Schulze TG, Nöthen MM, Cichon S, Rietschel M, Wüst S.

Int J Neuropsychopharmacol. 2013 Apr;16(3):549-56. doi: 10.1017/S1461145712000697. Epub 2012 Jul 25.

PMID:
22831755
16.

Identification and functional studies of regulatory variants responsible for the association of NRG3 with a delusion phenotype in schizophrenia.

Zeledón M, Eckart N, Taub M, Vernon H, Szymanksi M, Wang R, Chen PL, Nestadt G, McGrath JA, Sawa A, Pulver AE, Avramopoulos D, Valle D.

Mol Neuropsychiatry. 2015 May;1(1):36-46. Epub 2015 Feb 27.

17.

Biological validation of increased schizophrenia risk with NRG1, ERBB4, and AKT1 epistasis via functional neuroimaging in healthy controls.

Nicodemus KK, Law AJ, Radulescu E, Luna A, Kolachana B, Vakkalanka R, Rujescu D, Giegling I, Straub RE, McGee K, Gold B, Dean M, Muglia P, Callicott JH, Tan HY, Weinberger DR.

Arch Gen Psychiatry. 2010 Oct;67(10):991-1001. doi: 10.1001/archgenpsychiatry.2010.117.

18.

Neuregulin 1-ErbB4-PI3K signaling in schizophrenia and phosphoinositide 3-kinase-p110δ inhibition as a potential therapeutic strategy.

Law AJ, Wang Y, Sei Y, O'Donnell P, Piantadosi P, Papaleo F, Straub RE, Huang W, Thomas CJ, Vakkalanka R, Besterman AD, Lipska BK, Hyde TM, Harrison PJ, Kleinman JE, Weinberger DR.

Proc Natl Acad Sci U S A. 2012 Jul 24;109(30):12165-70. doi: 10.1073/pnas.1206118109. Epub 2012 Jun 11.

19.

Interactions among genes in the ErbB-Neuregulin signalling network are associated with increased susceptibility to schizophrenia.

Benzel I, Bansal A, Browning BL, Galwey NW, Maycox PR, McGinnis R, Smart D, St Clair D, Yates P, Purvis I.

Behav Brain Funct. 2007 Jun 28;3:31.

20.

Cognitive outcome and gamma noise power unrelated to neuregulin 1 and 3 variation in schizophrenia.

Díez A, Cieza-Borrella C, Suazo V, González-Sarmiento R, Papiol S, Molina V.

Ann Gen Psychiatry. 2014 Jun 14;13:18. doi: 10.1186/1744-859X-13-18. eCollection 2014.

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