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RIP1 kinase mediates arachidonic acid-induced oxidative death of oligodendrocyte precursors.

Kim S, Dayani L, Rosenberg PA, Li J.

Int J Physiol Pathophysiol Pharmacol. 2010;2(2):137-47. Epub 2010 Jun 12.


12-Lipoxygenase plays a key role in cell death caused by glutathione depletion and arachidonic acid in rat oligodendrocytes.

Wang H, Li J, Follett PL, Zhang Y, Cotanche DA, Jensen FE, Volpe JJ, Rosenberg PA.

Eur J Neurosci. 2004 Oct;20(8):2049-58.


Vitamin K prevents oxidative cell death by inhibiting activation of 12-lipoxygenase in developing oligodendrocytes.

Li J, Wang H, Rosenberg PA.

J Neurosci Res. 2009 Jul;87(9):1997-2005. doi: 10.1002/jnr.22029.


Identification of RIP1 kinase as a specific cellular target of necrostatins.

Degterev A, Hitomi J, Germscheid M, Ch'en IL, Korkina O, Teng X, Abbott D, Cuny GD, Yuan C, Wagner G, Hedrick SM, Gerber SA, Lugovskoy A, Yuan J.

Nat Chem Biol. 2008 May;4(5):313-21. doi: 10.1038/nchembio.83.


The inhibition of ERK activation mediates the protection of necrostatin-1 on glutamate toxicity in HT-22 cells.

Zhang M, Li J, Geng R, Ge W, Zhou Y, Zhang C, Cheng Y, Geng D.

Neurotox Res. 2013 Jul;24(1):64-70. doi: 10.1007/s12640-012-9361-4. Epub 2013 Jan 10.


Caspase blockade induces RIP3-mediated programmed necrosis in Toll-like receptor-activated microglia.

Kim SJ, Li J.

Cell Death Dis. 2013 Jul 11;4:e716. doi: 10.1038/cddis.2013.238.


Glutathione and antioxidant enzymes serve complementary roles in protecting activated hepatic stellate cells against hydrogen peroxide-induced cell death.

Dunning S, Ur Rehman A, Tiebosch MH, Hannivoort RA, Haijer FW, Woudenberg J, van den Heuvel FA, Buist-Homan M, Faber KN, Moshage H.

Biochim Biophys Acta. 2013 Dec;1832(12):2027-34. doi: 10.1016/j.bbadis.2013.07.008. Epub 2013 Jul 16.


RIP1-mediated mitochondrial dysfunction and ROS production contributed to tumor necrosis factor alpha-induced L929 cell necroptosis and autophagy.

Ye YC, Wang HJ, Yu L, Tashiro S, Onodera S, Ikejima T.

Int Immunopharmacol. 2012 Dec;14(4):674-82. doi: 10.1016/j.intimp.2012.08.003. Epub 2012 Sep 20.


Palmitate induces RIP1-dependent necrosis in RAW 264.7 cells.

Kim SK, Seo G, Oh E, Jin SH, Chae GT, Lee SB.

Atherosclerosis. 2012 Dec;225(2):315-21. doi: 10.1016/j.atherosclerosis.2012.09.021. Epub 2012 Sep 29.


RIP1 potentiates BPDE-induced transformation in human bronchial epithelial cells through catalase-mediated suppression of excessive reactive oxygen species.

Wang Q, Chen W, Xu X, Li B, He W, Padilla MT, Jang JH, Nyunoya T, Amin S, Wang X, Lin Y.

Carcinogenesis. 2013 Sep;34(9):2119-28. doi: 10.1093/carcin/bgt143. Epub 2013 Apr 30.


Structural basis of RIP1 inhibition by necrostatins.

Xie T, Peng W, Liu Y, Yan C, Maki J, Degterev A, Yuan J, Shi Y.

Structure. 2013 Mar 5;21(3):493-9. doi: 10.1016/j.str.2013.01.016.


RIP1-dependent and independent effects of necrostatin-1 in necrosis and T cell activation.

Cho Y, McQuade T, Zhang H, Zhang J, Chan FK.

PLoS One. 2011;6(8):e23209. doi: 10.1371/journal.pone.0023209. Epub 2011 Aug 10.


Novel role of vitamin k in preventing oxidative injury to developing oligodendrocytes and neurons.

Li J, Lin JC, Wang H, Peterson JW, Furie BC, Furie B, Booth SL, Volpe JJ, Rosenberg PA.

J Neurosci. 2003 Jul 2;23(13):5816-26.


Astrocytes promote TNF-mediated toxicity to oligodendrocyte precursors.

Kim S, Steelman AJ, Koito H, Li J.

J Neurochem. 2011 Jan;116(1):53-66. doi: 10.1111/j.1471-4159.2010.07084.x. Epub 2010 Dec 2.


cIAP1 and TAK1 protect cells from TNF-induced necrosis by preventing RIP1/RIP3-dependent reactive oxygen species production.

Vanlangenakker N, Vanden Berghe T, Bogaert P, Laukens B, Zobel K, Deshayes K, Vucic D, Fulda S, Vandenabeele P, Bertrand MJ.

Cell Death Differ. 2011 Apr;18(4):656-65. doi: 10.1038/cdd.2010.138. Epub 2010 Nov 5.


Necroptosis is a key mediator of enterocytes loss in intestinal ischaemia/reperfusion injury.

Wen S, Ling Y, Yang W, Shen J, Li C, Deng W, Liu W, Liu K.

J Cell Mol Med. 2016 Sep 28. doi: 10.1111/jcmm.12987. [Epub ahead of print]

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