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Items: 1 to 20 of 97

1.

Rb regulates fate choice and lineage commitment in vivo.

Calo E, Quintero-Estades JA, Danielian PS, Nedelcu S, Berman SD, Lees JA.

Nature. 2010 Aug 26;466(7310):1110-4. doi: 10.1038/nature09264. Epub 2010 Aug 4.

PMID:
20686481
2.

Rb and p107 regulate preadipocyte differentiation into white versus brown fat through repression of PGC-1alpha.

Scimè A, Grenier G, Huh MS, Gillespie MA, Bevilacqua L, Harper ME, Rudnicki MA.

Cell Metab. 2005 Nov;2(5):283-95.

PMID:
16271529
3.

Increased mitochondrial function downstream from KDM5A histone demethylase rescues differentiation in pRB-deficient cells.

Váraljai R, Islam AB, Beshiri ML, Rehman J, Lopez-Bigas N, Benevolenskaya EV.

Genes Dev. 2015 Sep 1;29(17):1817-34. doi: 10.1101/gad.264036.115. Epub 2015 Aug 27.

PMID:
26314709
4.

p107 is a crucial regulator for determining the adipocyte lineage fate choices of stem cells.

De Sousa M, Porras DP, Perry CG, Seale P, Scimè A.

Stem Cells. 2014 May;32(5):1323-36. doi: 10.1002/stem.1637.

PMID:
24449206
5.

The retinoblastoma protein tumor suppressor is important for appropriate osteoblast differentiation and bone development.

Berman SD, Yuan TL, Miller ES, Lee EY, Caron A, Lees JA.

Mol Cancer Res. 2008 Sep;6(9):1440-51. doi: 10.1158/1541-7786.MCR-08-0176.

PMID:
18819932
6.

Activity of the retinoblastoma family proteins, pRB, p107, and p130, during cellular proliferation and differentiation.

Sidle A, Palaty C, Dirks P, Wiggan O, Kiess M, Gill RM, Wong AK, Hamel PA.

Crit Rev Biochem Mol Biol. 1996 Jun;31(3):237-71. Review.

PMID:
8817077
7.

RB family tumor suppressor activity may not relate to active silencing of E2F target genes.

Vormer TL, Wojciechowicz K, Dekker M, de Vries S, van der Wal A, Delzenne-Goette E, Naik SH, Song JY, Dannenberg JH, Hansen JB, Te Riele H.

Cancer Res. 2014 Sep 15;74(18):5266-76. doi: 10.1158/0008-5472.CAN-13-3706. Epub 2014 Jul 23.

PMID:
25056122
8.

Stable binding to E2F is not required for the retinoblastoma protein to activate transcription, promote differentiation, and suppress tumor cell growth.

Sellers WR, Novitch BG, Miyake S, Heith A, Otterson GA, Kaye FJ, Lassar AB, Kaelin WG Jr.

Genes Dev. 1998 Jan 1;12(1):95-106.

PMID:
9420334
9.

Involvement of the retinoblastoma protein in brown and white adipocyte cell differentiation: functional and physical association with the adipogenic transcription factor C/EBPalpha.

Puigserver P, Ribot J, Serra F, Gianotti M, Bonet ML, Nadal-Ginard B, Palou A.

Eur J Cell Biol. 1998 Oct;77(2):117-23.

PMID:
9840461
10.

The retinoblastoma protein acts as a transcriptional coactivator required for osteogenic differentiation.

Thomas DM, Carty SA, Piscopo DM, Lee JS, Wang WF, Forrester WC, Hinds PW.

Mol Cell. 2001 Aug;8(2):303-16.

PMID:
11545733
11.

Brown vs white adipocytes: the PPARgamma coregulator story.

Koppen A, Kalkhoven E.

FEBS Lett. 2010 Aug 4;584(15):3250-9. doi: 10.1016/j.febslet.2010.06.035. Epub 2010 Jun 30. Review.

PMID:
20600006
12.

Regulation of cellular genes in a chromosomal context by the retinoblastoma tumor suppressor protein.

Buchmann AM, Swaminathan S, Thimmapaya B.

Mol Cell Biol. 1998 Aug;18(8):4565-76.

PMID:
9671466
13.

Terminal osteoblast differentiation, mediated by runx2 and p27KIP1, is disrupted in osteosarcoma.

Thomas DM, Johnson SA, Sims NA, Trivett MK, Slavin JL, Rubin BP, Waring P, McArthur GA, Walkley CR, Holloway AJ, Diyagama D, Grim JE, Clurman BE, Bowtell DD, Lee JS, Gutierrez GM, Piscopo DM, Carty SA, Hinds PW.

J Cell Biol. 2004 Dec 6;167(5):925-34.

PMID:
15583032
14.

HES1 cooperates with pRb to activate RUNX2-dependent transcription.

Lee JS, Thomas DM, Gutierrez G, Carty SA, Yanagawa S, Hinds PW.

J Bone Miner Res. 2006 Jun;21(6):921-33.

PMID:
16753023
15.

Activation of peroxisome proliferator-activated receptor gamma bypasses the function of the retinoblastoma protein in adipocyte differentiation.

Hansen JB, Petersen RK, Larsen BM, Bartkova J, Alsner J, Kristiansen K.

J Biol Chem. 1999 Jan 22;274(4):2386-93.

PMID:
9891007
16.

Retinoblastoma protein partners.

Morris EJ, Dyson NJ.

Adv Cancer Res. 2001;82:1-54. Review.

PMID:
11447760
17.

Loss of E2F-1 reduces tumorigenesis and extends the lifespan of Rb1(+/-)mice.

Yamasaki L, Bronson R, Williams BO, Dyson NJ, Harlow E, Jacks T.

Nat Genet. 1998 Apr;18(4):360-4.

PMID:
9537419
18.

A role for the retinoblastoma protein as a regulator of mouse osteoblast cell adhesion: implications for osteogenesis and osteosarcoma formation.

Sosa-García B, Gunduz V, Vázquez-Rivera V, Cress WD, Wright G, Bian H, Hinds PW, Santiago-Cardona PG.

PLoS One. 2010 Nov 11;5(11):e13954. doi: 10.1371/journal.pone.0013954.

PMID:
21085651
19.

Retinoic acid regulates commitment of undifferentiated mesenchymal stem cells into osteoblasts and adipocytes.

Hisada K, Hata K, Ichida F, Matsubara T, Orimo H, Nakano T, Yatani H, Nishimura R, Yoneda T.

J Bone Miner Metab. 2013 Jan;31(1):53-63. doi: 10.1007/s00774-012-0385-x. Epub 2012 Sep 27.

PMID:
23014973
20.

Impaired bone development and increased mesenchymal progenitor cells in calvaria of RB1-/- mice.

Gutierrez GM, Kong E, Sabbagh Y, Brown NE, Lee JS, Demay MB, Thomas DM, Hinds PW.

Proc Natl Acad Sci U S A. 2008 Nov 25;105(47):18402-7. doi: 10.1073/pnas.0805925105. Epub 2008 Nov 19.

PMID:
19020086

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