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Items: 1 to 20 of 114

1.

HCMV-encoded chemokine receptor US28 mediates proliferative signaling through the IL-6-STAT3 axis.

Slinger E, Maussang D, Schreiber A, Siderius M, Rahbar A, Fraile-Ramos A, Lira SA, Söderberg-Nauclér C, Smit MJ.

Sci Signal. 2010 Aug 3;3(133):ra58. doi: 10.1126/scisignal.2001180.

2.

Human cytomegalovirus-encoded chemokine receptor US28 promotes tumorigenesis.

Maussang D, Verzijl D, van Walsum M, Leurs R, Holl J, Pleskoff O, Michel D, van Dongen GA, Smit MJ.

Proc Natl Acad Sci U S A. 2006 Aug 29;103(35):13068-73. Epub 2006 Aug 21.

3.

Human cytomegalovirus encoded chemokine receptor US28 activates the HIF-1α/PKM2 axis in glioblastoma cells.

de Wit RH, Mujić-Delić A, van Senten JR, Fraile-Ramos A, Siderius M, Smit MJ.

Oncotarget. 2016 Oct 18;7(42):67966-67985. doi: 10.18632/oncotarget.11817.

4.

Human cytomegalovirus US28 found in glioblastoma promotes an invasive and angiogenic phenotype.

Soroceanu L, Matlaf L, Bezrookove V, Harkins L, Martinez R, Greene M, Soteropoulos P, Cobbs CS.

Cancer Res. 2011 Nov 1;71(21):6643-53. doi: 10.1158/0008-5472.CAN-11-0744. Epub 2011 Sep 7.

5.

The human cytomegalovirus-encoded chemokine receptor US28 promotes angiogenesis and tumor formation via cyclooxygenase-2.

Maussang D, Langemeijer E, Fitzsimons CP, Stigter-van Walsum M, Dijkman R, Borg MK, Slinger E, Schreiber A, Michel D, Tensen CP, van Dongen GA, Leurs R, Smit MJ.

Cancer Res. 2009 Apr 1;69(7):2861-9. doi: 10.1158/0008-5472.CAN-08-2487. Epub 2009 Mar 24.

6.

JAK1 activates STAT3 activity in non-small-cell lung cancer cells and IL-6 neutralizing antibodies can suppress JAK1-STAT3 signaling.

Song L, Rawal B, Nemeth JA, Haura EB.

Mol Cancer Ther. 2011 Mar;10(3):481-94. doi: 10.1158/1535-7163.MCT-10-0502. Epub 2011 Jan 7.

7.

The carboxy-terminal tail of human cytomegalovirus (HCMV) US28 regulates both chemokine-independent and chemokine-dependent signaling in HCMV-infected cells.

Stropes MP, Schneider OD, Zagorski WA, Miller JL, Miller WE.

J Virol. 2009 Oct;83(19):10016-27. doi: 10.1128/JVI.00354-09. Epub 2009 Jul 15.

8.

Human Cytomegalovirus US28: a functionally selective chemokine binding receptor.

Vomaske J, Nelson JA, Streblow DN.

Infect Disord Drug Targets. 2009 Nov;9(5):548-56. Review.

9.
10.

LIF-JAK1-STAT3 signaling delays contact inhibition of human corneal endothelial cells.

Liu X, Tseng SC, Zhang MC, Chen SY, Tighe S, Lu WJ, Zhu YT.

Cell Cycle. 2015;14(8):1197-206. doi: 10.1080/15384101.2015.1013667.

11.

Role of MMP-2 in the regulation of IL-6/Stat3 survival signaling via interaction with α5β1 integrin in glioma.

Kesanakurti D, Chetty C, Dinh DH, Gujrati M, Rao JS.

Oncogene. 2013 Jan 17;32(3):327-40. doi: 10.1038/onc.2012.52. Epub 2012 Feb 20.

12.

Activation of IL-6R/JAK1/STAT3 signaling induces de novo resistance to irreversible EGFR inhibitors in non-small cell lung cancer with T790M resistance mutation.

Kim SM, Kwon OJ, Hong YK, Kim JH, Solca F, Ha SJ, Soo RA, Christensen JG, Lee JH, Cho BC.

Mol Cancer Ther. 2012 Oct;11(10):2254-64. doi: 10.1158/1535-7163.MCT-12-0311. Epub 2012 Aug 13.

14.

HCMV activates the IL-6-JAK-STAT3 axis in HepG2 cells and primary human hepatocytes.

Lepiller Q, Abbas W, Kumar A, Tripathy MK, Herbein G.

PLoS One. 2013;8(3):e59591. doi: 10.1371/journal.pone.0059591. Epub 2013 Mar 26. Erratum in: PLoS One. 2013;8(5). doi:10.1371/annotation/35a1ab77-2ece-4fc7-9f1e-11c276f9d7c8.

15.

HB-EGF induces delayed STAT3 activation via NF-kappaB mediated IL-6 secretion in vascular smooth muscle cell.

Lee KS, Park JH, Lee S, Lim HJ, Choi HE, Park HY.

Biochim Biophys Acta. 2007 Nov;1773(11):1637-44. Epub 2007 Jul 17.

16.

Human Cytomegalovirus-Encoded Receptor US28 Is Expressed in Renal Allografts and Facilitates Viral Spreading In Vitro.

Lollinga WT, de Wit RH, Rahbar A, Vasse GF, Davoudi B, Diepstra A, Riezebos-Brilman A, Harmsen MC, Hillebrands JL, Söderberg-Naucler C, van Son WJ, Smit MJ, Sanders JS, van den Born J.

Transplantation. 2017 Mar;101(3):531-540. doi: 10.1097/TP.0000000000001289.

PMID:
27362315
17.

Emodin inhibits growth and induces apoptosis in an orthotopic hepatocellular carcinoma model by blocking activation of STAT3.

Subramaniam A, Shanmugam MK, Ong TH, Li F, Perumal E, Chen L, Vali S, Abbasi T, Kapoor S, Ahn KS, Kumar AP, Hui KM, Sethi G.

Br J Pharmacol. 2013 Oct;170(4):807-21. doi: 10.1111/bph.12302.

18.

CC and CX3C chemokines differentially interact with the N terminus of the human cytomegalovirus-encoded US28 receptor.

Casarosa P, Waldhoer M, LiWang PJ, Vischer HF, Kledal T, Timmerman H, Schwartz TW, Smit MJ, Leurs R.

J Biol Chem. 2005 Feb 4;280(5):3275-85. Epub 2004 Nov 16.

19.

Quercetin abrogates IL-6/STAT3 signaling and inhibits glioblastoma cell line growth and migration.

Michaud-Levesque J, Bousquet-Gagnon N, Béliveau R.

Exp Cell Res. 2012 May 1;318(8):925-35. doi: 10.1016/j.yexcr.2012.02.017. Epub 2012 Feb 26.

PMID:
22394507
20.

Honokiol inhibits signal transducer and activator of transcription-3 signaling, proliferation, and survival of hepatocellular carcinoma cells via the protein tyrosine phosphatase SHP-1.

Rajendran P, Li F, Shanmugam MK, Vali S, Abbasi T, Kapoor S, Ahn KS, Kumar AP, Sethi G.

J Cell Physiol. 2012 May;227(5):2184-95. doi: 10.1002/jcp.22954.

PMID:
21792937

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