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Cytokines and growth factors stimulate hyaluronan production: role of hyaluronan in epithelial to mesenchymal-like transition in non-small cell lung cancer.

Chow G, Tauler J, Mulshine JL.

J Biomed Biotechnol. 2010;2010:485468. doi: 10.1155/2010/485468. Epub 2010 Jun 30.


Transforming growth factor-β1 induces EMT by the transactivation of epidermal growth factor signaling through HA/CD44 in lung and breast cancer cells.

Li L, Qi L, Liang Z, Song W, Liu Y, Wang Y, Sun B, Zhang B, Cao W.

Int J Mol Med. 2015 Jul;36(1):113-22. doi: 10.3892/ijmm.2015.2222. Epub 2015 May 25.


Epithelial to mesenchymal transition derived from repeated exposure to gefitinib determines the sensitivity to EGFR inhibitors in A549, a non-small cell lung cancer cell line.

Rho JK, Choi YJ, Lee JK, Ryoo BY, Na II, Yang SH, Kim CH, Lee JC.

Lung Cancer. 2009 Feb;63(2):219-26. doi: 10.1016/j.lungcan.2008.05.017. Epub 2008 Jul 2.


Interleukin-1 beta and transforming growth factor-beta 3 cooperate to activate matrix metalloproteinase expression and invasiveness in A549 lung adenocarcinoma cells.

Petrella BL, Armstrong DA, Vincenti MP.

Cancer Lett. 2012 Dec 28;325(2):220-6. doi: 10.1016/j.canlet.2012.07.009. Epub 2012 Jul 13.


Resveratrol inhibits TGF-β1-induced epithelial-to-mesenchymal transition and suppresses lung cancer invasion and metastasis.

Wang H, Zhang H, Tang L, Chen H, Wu C, Zhao M, Yang Y, Chen X, Liu G.

Toxicology. 2013 Jan 7;303:139-46. doi: 10.1016/j.tox.2012.09.017. Epub 2012 Nov 9.


Implication of epithelial-mesenchymal transition in IGF1R-induced resistance to EGFR-TKIs in advanced non-small cell lung cancer.

Zhou J, Wang J, Zeng Y, Zhang X, Hu Q, Zheng J, Chen B, Xie B, Zhang WM.

Oncotarget. 2015 Dec 29;6(42):44332-45. doi: 10.18632/oncotarget.6293.


MiR-134/487b/655 cluster regulates TGF-β-induced epithelial-mesenchymal transition and drug resistance to gefitinib by targeting MAGI2 in lung adenocarcinoma cells.

Kitamura K, Seike M, Okano T, Matsuda K, Miyanaga A, Mizutani H, Noro R, Minegishi Y, Kubota K, Gemma A.

Mol Cancer Ther. 2014 Feb;13(2):444-53. doi: 10.1158/1535-7163.MCT-13-0448. Epub 2013 Nov 20.


Derlin-1 is overexpressed in non-small cell lung cancer and promotes cancer cell invasion via EGFR-ERK-mediated up-regulation of MMP-2 and MMP-9.

Dong QZ, Wang Y, Tang ZP, Fu L, Li QC, Wang ED, Wang EH.

Am J Pathol. 2013 Mar;182(3):954-64. doi: 10.1016/j.ajpath.2012.11.019. Epub 2013 Jan 7.


Epithelial to mesenchymal transition is a determinant of sensitivity of non-small-cell lung carcinoma cell lines and xenografts to epidermal growth factor receptor inhibition.

Thomson S, Buck E, Petti F, Griffin G, Brown E, Ramnarine N, Iwata KK, Gibson N, Haley JD.

Cancer Res. 2005 Oct 15;65(20):9455-62.


Up-regulation of sonic hedgehog contributes to TGF-β1-induced epithelial to mesenchymal transition in NSCLC cells.

Maitah MY, Ali S, Ahmad A, Gadgeel S, Sarkar FH.

PLoS One. 2011 Jan 13;6(1):e16068. doi: 10.1371/journal.pone.0016068.


EGCG inhibits transforming growth factor-β-mediated epithelial-to-mesenchymal transition via the inhibition of Smad2 and Erk1/2 signaling pathways in nonsmall cell lung cancer cells.

Liu LC, Tsao TC, Hsu SR, Wang HC, Tsai TC, Kao JY, Way TD.

J Agric Food Chem. 2012 Oct 3;60(39):9863-73. doi: 10.1021/jf303690x. Epub 2012 Sep 19.


Thyroid transcription factor-1 inhibits transforming growth factor-beta-mediated epithelial-to-mesenchymal transition in lung adenocarcinoma cells.

Saito RA, Watabe T, Horiguchi K, Kohyama T, Saitoh M, Nagase T, Miyazono K.

Cancer Res. 2009 Apr 1;69(7):2783-91. doi: 10.1158/0008-5472.CAN-08-3490. Epub 2009 Mar 17.


Interaction between non-small-cell lung cancer cells and fibroblasts via enhancement of TGF-β signaling by IL-6.

Abulaiti A, Shintani Y, Funaki S, Nakagiri T, Inoue M, Sawabata N, Minami M, Okumura M.

Lung Cancer. 2013 Nov;82(2):204-13. doi: 10.1016/j.lungcan.2013.08.008. Epub 2013 Aug 19.


Activation of EGFR promotes squamous carcinoma SCC10A cell migration and invasion via inducing EMT-like phenotype change and MMP-9-mediated degradation of E-cadherin.

Zuo JH, Zhu W, Li MY, Li XH, Yi H, Zeng GQ, Wan XX, He QY, Li JH, Qu JQ, Chen Y, Xiao ZQ.

J Cell Biochem. 2011 Sep;112(9):2508-17. doi: 10.1002/jcb.23175.


Inhibition of oesophageal squamous cell carcinoma progression by in vivo targeting of hyaluronan synthesis.

Twarock S, Freudenberger T, Poscher E, Dai G, Jannasch K, Dullin C, Alves F, Prenzel K, Knoefel WT, Stoecklein NH, Savani RC, Homey B, Fischer JW.

Mol Cancer. 2011 Mar 23;10:30. doi: 10.1186/1476-4598-10-30.


Inhibition of ZNF746 suppresses invasion and epithelial to mesenchymal transition in H460 non-small cell lung cancer cells.

Kim B, Sohn EJ, Jung JH, Shin EA, You OH, Im J, Kim SH.

Oncol Rep. 2014 Jan;31(1):73-8. doi: 10.3892/or.2013.2801. Epub 2013 Oct 22.


Hyaluronan facilitates transforming growth factor-β1-dependent proliferation via CD44 and epidermal growth factor receptor interaction.

Meran S, Luo DD, Simpson R, Martin J, Wells A, Steadman R, Phillips AO.

J Biol Chem. 2011 May 20;286(20):17618-30. doi: 10.1074/jbc.M111.226563. Epub 2011 Mar 25.

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