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Items: 1 to 20 of 134

1.

Activation of alpha4* nAChRs is necessary and sufficient for varenicline-induced reduction of alcohol consumption.

Hendrickson LM, Zhao-Shea R, Pang X, Gardner PD, Tapper AR.

J Neurosci. 2010 Jul 28;30(30):10169-76. doi: 10.1523/JNEUROSCI.2601-10.2010.

2.

Nicotine-mediated activation of dopaminergic neurons in distinct regions of the ventral tegmental area.

Zhao-Shea R, Liu L, Soll LG, Improgo MR, Meyers EE, McIntosh JM, Grady SR, Marks MJ, Gardner PD, Tapper AR.

Neuropsychopharmacology. 2011 Apr;36(5):1021-32. doi: 10.1038/npp.2010.240. Epub 2011 Feb 2.

3.
4.

Modulation of ethanol consumption by genetic and pharmacological manipulation of nicotinic acetylcholine receptors in mice.

Kamens HM, Andersen J, Picciotto MR.

Psychopharmacology (Berl). 2010 Mar;208(4):613-26. doi: 10.1007/s00213-009-1759-1.

5.

Nicotinic acetylcholine receptors containing the α4 subunit modulate alcohol reward.

Liu L, Hendrickson LM, Guildford MJ, Zhao-Shea R, Gardner PD, Tapper AR.

Biol Psychiatry. 2013 Apr 15;73(8):738-46. doi: 10.1016/j.biopsych.2012.09.019. Epub 2012 Nov 9.

6.

Functional Upregulation of α4* Nicotinic Acetylcholine Receptors in VTA GABAergic Neurons Increases Sensitivity to Nicotine Reward.

Ngolab J, Liu L, Zhao-Shea R, Gao G, Gardner PD, Tapper AR.

J Neurosci. 2015 Jun 3;35(22):8570-8. doi: 10.1523/JNEUROSCI.4453-14.2015.

7.

A role for α4(non-α6)* nicotinic acetylcholine receptors in motor behavior.

Soll LG, Grady SR, Salminen O, Marks MJ, Tapper AR.

Neuropharmacology. 2013 Oct;73:19-30. doi: 10.1016/j.neuropharm.2013.05.001. Epub 2013 May 17.

8.

Nicotinic acetylcholine receptors containing the α6 subunit contribute to ethanol activation of ventral tegmental area dopaminergic neurons.

Liu L, Zhao-Shea R, McIntosh JM, Tapper AR.

Biochem Pharmacol. 2013 Oct 15;86(8):1194-200. doi: 10.1016/j.bcp.2013.06.015. Epub 2013 Jun 26.

9.

Varenicline decreases ethanol intake and increases dopamine release via neuronal nicotinic acetylcholine receptors in the nucleus accumbens.

Feduccia AA, Simms JA, Mill D, Yi HY, Bartlett SE.

Br J Pharmacol. 2014 Jul;171(14):3420-31. doi: 10.1111/bph.12690.

10.

Nicotine persistently activates ventral tegmental area dopaminergic neurons via nicotinic acetylcholine receptors containing α4 and α6 subunits.

Liu L, Zhao-Shea R, McIntosh JM, Gardner PD, Tapper AR.

Mol Pharmacol. 2012 Apr;81(4):541-8. doi: 10.1124/mol.111.076661. Epub 2012 Jan 5.

11.

Crucial role of alpha4 and alpha6 nicotinic acetylcholine receptor subunits from ventral tegmental area in systemic nicotine self-administration.

Pons S, Fattore L, Cossu G, Tolu S, Porcu E, McIntosh JM, Changeux JP, Maskos U, Fratta W.

J Neurosci. 2008 Nov 19;28(47):12318-27. doi: 10.1523/JNEUROSCI.3918-08.2008.

12.
13.

The α5 subunit regulates the expression and function of α4*-containing neuronal nicotinic acetylcholine receptors in the ventral-tegmental area.

Chatterjee S, Santos N, Holgate J, Haass-Koffler CL, Hopf FW, Kharazia V, Lester H, Bonci A, Bartlett SE.

PLoS One. 2013 Jul 15;8(7):e68300. doi: 10.1371/journal.pone.0068300. Print 2013.

14.

Nicotine and ethanol cooperate to enhance ventral tegmental area AMPA receptor function via α6-containing nicotinic receptors.

Engle SE, McIntosh JM, Drenan RM.

Neuropharmacology. 2015 Apr;91:13-22. doi: 10.1016/j.neuropharm.2014.11.014. Epub 2014 Dec 4.

15.

Distinctive nicotinic acetylcholine receptor functional phenotypes of rat ventral tegmental area dopaminergic neurons.

Yang K, Hu J, Lucero L, Liu Q, Zheng C, Zhen X, Jin G, Lukas RJ, Wu J.

J Physiol. 2009 Jan 15;587(2):345-61. doi: 10.1113/jphysiol.2008.162743. Epub 2008 Dec 1.

16.

Nicotinic acetylcholine receptors containing α6 subunits contribute to alcohol reward-related behaviours.

Powers MS, Broderick HJ, Drenan RM, Chester JA.

Genes Brain Behav. 2013 Jul;12(5):543-53. doi: 10.1111/gbb.12042. Epub 2013 May 7.

17.

Partial agonists of the α3β4* neuronal nicotinic acetylcholine receptor reduce ethanol consumption and seeking in rats.

Chatterjee S, Steensland P, Simms JA, Holgate J, Coe JW, Hurst RS, Shaffer CL, Lowe J, Rollema H, Bartlett SE.

Neuropsychopharmacology. 2011 Feb;36(3):603-15. doi: 10.1038/npp.2010.191. Epub 2010 Nov 3.

18.

Varenicline blocks β2*-nAChR-mediated response and activates β4*-nAChR-mediated responses in mice in vivo.

Ortiz NC, O'Neill HC, Marks MJ, Grady SR.

Nicotine Tob Res. 2012 Jun;14(6):711-9. doi: 10.1093/ntr/ntr284. Epub 2012 Jan 12.

19.

Varenicline reduces alcohol self-administration in heavy-drinking smokers.

McKee SA, Harrison EL, O'Malley SS, Krishnan-Sarin S, Shi J, Tetrault JM, Picciotto MR, Petrakis IL, Estevez N, Balchunas E.

Biol Psychiatry. 2009 Jul 15;66(2):185-90. doi: 10.1016/j.biopsych.2009.01.029. Epub 2009 Feb 27.

20.

Molecular and physiological diversity of nicotinic acetylcholine receptors in the midbrain dopaminergic nuclei.

Klink R, de Kerchove d'Exaerde A, Zoli M, Changeux JP.

J Neurosci. 2001 Mar 1;21(5):1452-63.

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